R. Cecchelli

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Aliases
Roméo Cecchelli, R Cecchelli, Romeo Cecchelli, R. Cecchelli, Roméo Cecchelli
Publication record
190 papers · 13,024 citations · H-index 61

PAPERS

Derivation of Brain Capillary-like Endothelial Cells from Human Pluripotent Stem Cell-Derived Endothelial Progenitor Cells
201952 citationsauthor #4
A nanoformulation for the preferential accumulation in adult neurogenic niches
201835 citationsauthor #6
Innentitelbild: MiniAp‐4: A Venom‐Inspired Peptidomimetic for Brain Delivery (Angew. Chem. 2/2016)
20161 citationsauthor #8
Stem Cell-Based Human Blood-Brain Barrier Models for Drug Discovery and Delivery.
2016146 citationsauthor #2
In vitro models of the blood–brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use
2016605 citationsauthor #4
ST6GALNAC5 Expression Decreases the Interactions between Breast Cancer Cells and the Human Blood-Brain Barrier
201645 citationsauthor #6
Inside Cover: MiniAp‐4: A Venom‐Inspired Peptidomimetic for Brain Delivery (Angew. Chem. Int. Ed. 2/2016)
20162 citationsauthor #8
In vitro blood-brain barrier permeability predictions for GABAA receptor modulating piperine analogs.
201633 citationsauthor #7
Pharmacokinetics and In Vitro Blood-Brain Barrier Screening of the Plant-Derived Alkaloid Tryptanthrin
201620 citationsauthor #6
Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines
201632 citationsauthor #6
3 Evaluation of drug-induced neurotoxicity based on metabolomics, 4 proteomics and electrical activity measurements in complementary CNS
20150 citationsauthor #14
Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models.
201566 citationsauthor #14
MiniAp‐4: A Venom‐Inspired Peptidomimetic for Brain Delivery
201581 citationsauthor #8
Pharmacokinetic, in vitro and in silico assessment of anti-inflammatory alkaloids from Isatis tinctoria L.
20152 citationsauthor #7
A Stable and Reproducible Human Blood-Brain Barrier Model Derived from Hematopoietic Stem Cells
2014283 citationsauthor #1
Blood–Brain Barrier In Vitro Models and Their Applications in Toxicology
20140 citationsauthor #6
A new angle on blood–CNS interfaces: A role for connexins?
201483 citationsauthor #5
Blood-brain barrier proteomics: towards the understanding of neurodegenerative diseases.
201412 citationsauthor #4
Stroke-Induced Brain Parenchymal Injury Drives Blood–Brain Barrier Early Leakage Kinetics: A Combined in Vivo/in Vitro Study
201459 citationsauthor #8
Title : Development and validation of a LC-MS / MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models
20149 citationsauthor #4
Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models.
20148 citationsauthor #4
Protein kinase C restricts transport of carnitine by amino acid transporter ATB(0,+) apically localized in the blood-brain barrier.
201418 citationsauthor #7
Glial‐cell‐mediated re‐induction of the blood‐brain barrier phenotype in brain capillary endothelial cells: A differential gel electrophoresis study
201319 citationsauthor #10
A Simple Method for Assessing Free Brain/Free Plasma Ratios Using an In Vitro Model of the Blood Brain Barrier
201333 citationsauthor #8
Accelerated Caco-2 cell permeability model for drug discovery.
201378 citationsauthor #4
In vitro blood-brain barrier model adapted to repeated-dose toxicological screening.
201319 citationsauthor #5
Maternal calorie restriction modulates placental mitochondrial biogenesis and bioenergetic efficiency: putative involvement in fetoplacental growth defects in rats.
201366 citationsauthor #8
Endothelial calcium dynamics, connexin channels and blood-brain barrier function.
2013161 citationsauthor #7
The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox.
201339 citationsauthor #7
Proteomic Analysis of Plasma Membrane Proteins in an In Vitro Blood-Brain Barrier Model
20123 citationsauthor #4
TNAP and EHD1 Are Over-Expressed in Bovine Brain Capillary Endothelial Cells after the Re-Induction of Blood-Brain Barrier Properties
201229 citationsauthor #4
Lukaszewski , Sophie rats putative involvement in fetoplacental growth defects in mitochondrial biogenesis and bioenergetic efficiency : Maternal calorie restriction modulates placental
20120 citationsauthor #8
[Dysfunction of the blood-brain barrier during ischaemia: a therapeutic concern].
20123 citationsauthor #5
Endothelial Cells and Astrocytes: A Concerto en Duo in Ischemic Pathophysiology
201233 citationsauthor #3
Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro
201231 citationsauthor #8
Brain Pericytes ABCA1 Expression Mediates Cholesterol Efflux but not Cellular Amyloid-β Peptide Accumulation
201263 citationsauthor #6
Case study: adapting in vitro blood-brain barrier models for use in early-stage drug discovery.
201232 citationsauthor #5
Brain pericytes from stress-susceptible pigs increase blood-brain barrier permeability in vitro
20121 citationsauthor #8
In vitro blood–brain barrier model adapted to repeated dose toxicological screening
20111 citationsauthor #4
Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes.
201192 citationsauthor #9
Ready-to-use in vitro blood–brain barrier model
20110 citationsauthor #5
Connexin Channels Provide a Target to Manipulate Brain Endothelial Calcium Dynamics and Blood—Brain Barrier Permeability
2011144 citationsauthor #16
A differential proteomic approach identifies structural and functional components that contribute to the differentiation of brain capillary endothelial cells.
201123 citationsauthor #8
[Role of the blood-brain barrier in Alzheimer's disease].
201115 citationsauthor #3
HMGB-1 promotes fibrinolysis and reduces neurotoxicity mediated by tissue plasminogen activator
201132 citationsauthor #9
Modelling the Blood–Brain Barrier
20113 citationsauthor #9
Differential Roles for Endothelial ICAM-1, ICAM-2, and VCAM-1 in Shear-Resistant T Cell Arrest, Polarization, and Directed Crawling on Blood–Brain Barrier Endothelium
2010247 citationsauthor #3
Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein
2010127 citationsauthor #7
A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties
201017 citationsauthor #4
This information is current as Endothelium Brain Barrier − rawling on Blood Cell Arrest , Polarization , and Directed C ICAM-2 , and VCAM-1 in Shear-Resistant T Differential Roles for Endothelial ICAM-1
20102 citationsauthor #3
Understanding the blood-brain barrier using gene and protein expression profiling technologies.
200938 citationsauthor #3
P1‐011: Involvement of LRP1 and RAGE in the transport of β‐amyloid (Aβ) peptide across the blood‐brain barrier: Use of an in vitro model
2009290 citationsauthor #5
Engineering a GABA endowed with pharmacological CNS activity when given by an extracerebral route
200917 citationsauthor #9
Involvement of connexin hemichannels in dynamic calcium changes and permeability of blood-brain barrier endothelial cells
20090 citationsauthor #8
Actin, gelsolin and filamin‐A are dynamic actors in the cytoskeleton remodelling contributing to the blood brain barrier phenotype
200925 citationsauthor #3
Ca(2+) regulation of connexin 43 hemichannels in C6 glioma and glial cells.
2009195 citationsauthor #10
New strategy for alerting central nervous system toxicity: Integration of blood-brain barrier toxicity and permeability in neurotoxicity assessment.
200936 citationsauthor #7
Cerebrovascular protection as a possible mechanism for the protective effects of NXY-059 in preclinical models: an in vitro study.
200929 citationsauthor #7
Transcriptional profiles of receptors and transporters involved in brain cholesterol homeostasis at the blood-brain barrier: use of an in vitro model.
200985 citationsauthor #5
PPACK-Desmodus rotundus salivary plasminogen activator (cDSPAα1) prevents the passage of tissuetype plasminogen activator (rt-PA) across the blood-brain barrier and neurotoxicity
20095 citationsauthor #7
Peroxisome-proliferator-activated receptor-alpha activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier.
200920 citationsauthor #7
Peroxisome Proliferator-Activated Receptor-α Activation Protects Brain Capillary Endothelial Cells from Oxygen-Glucose Deprivation-Induced Hyperpermeability in the Blood-Brain Barrier
200956 citationsauthor #7
Physiological pathway for low-density lipoproteins across the blood-brain barrier: transcytosis through brain capillary endothelial cells in vitro.
2008109 citationsauthor #6
An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening.
2008136 citationsauthor #10
A polarized localization of amino acid/carnitine transporter B(0,+) (ATB(0,+)) in the blood-brain barrier.
200825 citationsauthor #6
Evidence of lowest brain penetration of an antiemetic drug, metopimazine, compared to domperidone, metoclopramide and chlorpromazine, using an in vitro model of the blood-brain barrier.
200757 citationsauthor #7
A versatile liposome/cyclodextrin supramolecular carrier for drug delivery through the blood-brain barrier
200713 citationsauthor #3
Localization of organic cation/carnitine transporter (OCTN2) in cells forming the blood–brain barrier
200770 citationsauthor #6
Modelling of the blood–brain barrier in drug discovery and development
2007605 citationsauthor #1
NP031112: An in vitro model confirms the BBB crossing
20070 citationsauthor #5
Modeling the Blood‐Brain Barrier
20075 citationsauthor #1
Recombinant Desmodus rotundus Salivary Plasminogen Activator Crosses the Blood–Brain Barrier Through a Low-Density Lipoprotein Receptor-Related Protein-Dependent Mechanism Without Exerting Neurotoxic Effects
200757 citationsauthor #7
Methylated β-cyclodextrin as P-gp modulators for deliverance of doxorubicin across an in vitro model of blood–brain barrier
200647 citationsauthor #5
Mycobacterium tuberculosis heparin-binding haemagglutinin adhesin (HBHA) triggers receptor-mediated transcytosis without altering the integrity of tight junctions.
2006108 citationsauthor #7
How cyclodextrins can mask their toxic effect on the blood-brain barrier.
200611 citationsauthor #4
Differential expression of selectins by mouse brain capillary endothelial cells in vitro in response to distinct inflammatory stimuli.
200633 citationsauthor #6
Highly purified lipoteichoic acid from gram-positive bacteria induces in vitro blood-brain barrier disruption through glia activation: role of pro-inflammatory cytokines and nitric oxide.
200667 citationsauthor #6
An Efficient Synthesis of New Spiro[indolo-3(1H),2′(3′H)-oxadiazolyl] and 1-(Triazol-4-ylmethyl)isatin Derivatives.
20062 citationsauthor #4
Methylated beta-cyclodextrin as P-gp modulators for deliverance of doxorubicin across an in vitro model of blood-brain barrier.
200611 citationsauthor #5
Transport studies of cationic lipids and antisense oligonucleotides lipoplexes across an in vitro model of the blood-brain barrier
20060 citationsauthor #5
Synthesis and Amphiphilic Behavior of N,N-Bis-glucosyl-1,5-benzodiazepin-2,4-diones.
20050 citationsauthor #7
VEGF-Induced BBB Permeability is Associated with an MMP-9 Activity Increase in Cerebral ischemia: Both Effects Decreased by ANG-1
2005196 citationsauthor #6
Oxygen Glucose Deprivation Switches the Transport of tPA Across the Blood–Brain Barrier From an LRP-Dependent to an Increased LRP-Independent Process
2005100 citationsauthor #7
Tissue-type plasminogen activator crosses the intact blood-brain barrier by LRP-mediated transcytosis: A phenomenon that is switched during oxygen glucose deprivation to an increased and LRP-independent process
20050 citationsauthor #11
Specific AHNAK expression in brain endothelial cells with barrier properties
200569 citationsauthor #6
The MAP kinase pathway mediates transcytosis induced by TNF‐α in an in vitro blood–brain barrier model
200543 citationsauthor #5
Adamantoylated monosaccharides: new compounds for modification of the properties of cyclodextrin-containing materials.
200510 citationsauthor #5
Tissue-Type Plasminogen Activator Crosses the Intact Blood-Brain Barrier by Low-Density Lipoprotein Receptor–Related Protein-Mediated Transcytosis
2005173 citationsauthor #11
Structural determination of the novel fragmentation routes of morphine opiate receptor antagonists using electrospray ionization quadrupole time-of-flight tandem mass spectrometry.
200517 citationsauthor #4
Induction of blood‐brain barrier properties in cultured brain capillary endothelial cells: Comparison between primary glial cells and C6 cell line
200580 citationsauthor #8
An efficient synthesis of new spiro[indolo-3(1H),2'(3'H)-oxadiazolyl] and 1-(triazol-4-ylmethyl)isatin derivatives
200522 citationsauthor #7
Mouse syngenic in vitro blood–brain barrier model: a new tool to examine inflammatory events in cerebral endothelium
2005191 citationsauthor #9
[Cerebral transfer and neuroprotection].
20040 citationsauthor #4
Blood-Brain Barrier In Vitro Models and Their Application in Toxicology: The Report and Recommendations of ECVAM Workshop 491,2
200438 citationsauthor #5
Involvement of OCTN2 and B0,+ in the transport of carnitine through an in vitro model of the blood–brain barrier
200433 citationsauthor #6
Transport Screening of Drug Cocktails Through an in Vitro Blood-Brain Barrier: Is It a Good Strategy for Increasing the Throughput of the Discovery Pipeline?
200433 citationsauthor #5
Synthesis of chacotriose analogues.
20043 citationsauthor #5
Novel Synthesis of Disaccharides Containing the 2-Amino-2-deoxy-β-D-glucopyranosyl Unit and L-Glycero-D-Manno- and 7-Deoxy-L-Glycero-D-Galacto-heptopyranoses
20045 citationsauthor #3
Behavior of alpha-, beta-, and gamma-cyclodextrins and their derivatives on an in vitro model of blood-brain barrier.
200430 citationsauthor #5
Physicochemical characterization and in vitro interaction with brain capillary endothelial cells of artificially monoacylated ribonucleases A
20041 citationsauthor #4

TIMELINE

1983 11 citations

1984 19 citations

1985 11 citations

1986 17 citations

1987 277 citations

1989 379 citations

1990 562 citations

1991 33 citations

1992 430 citations

1993 1 citations

1994 5 citations

1995 525 citations

1996 186 citations

1997 790 citations

1998 607 citations

1999 1,366 citations

2000 3 citations

2001 0 citations

2002 573 citations

2003 501 citations

2004 778 citations

2005 901 citations

2006 279 citations

2007 807 citations

2008 270 citations

2009 796 citations

2010 393 citations

2011 310 citations

2012 195 citations

2013 415 citations

2014 472 citations

2015 149 citations

2016 884 citations

2018 35 citations

2019 52 citations

R. Cecchelli

PROFILE

PAPERS

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