Advances in Industrial Biotechnology Using CRISPR-Cas Systems.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Trends in Biotechnology

• Publication date

  2017-08-01

• Fields of study

  Biology, Medicine, Engineering

• Identifiers
  DOI 10.1016/j.tibtech.2017.07.007PMID 28778606
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Development of a genome-editing CRISPR/Cas9 system in thermophilic fungal Myceliophthora species and its application to hyper-cellulase production strain engineering

  2017cited by this paper
• Standardized Markerless Gene Integration for Pathway Engineering in Yarrowia lipolytica.

  2017cited by this paper
• Diversity and evolution of class 2 CRISPR–Cas systems

  2017cited by this paper
• Efficient Genome Editing of a Facultative Thermophile Using Mesophilic spCas9

  2017cited by this paper
• Cas 13 b Is a Type VIB CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx 27 and Csx 28

  2017cited by this paper
• A thermostable Cas9 with increased lifetime in human plasma

  2017cited by this paper
• Corrigendum: DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression

  2016cited by this paper
• Assessing the global threat from Zika virus

  2016cited by this paper
• Structural Plasticity of PAM Recognition by Engineered Variants of the RNA-Guided Endonuclease Cas9.

  2016cited by this paper
• Bacterial Genome Editing with CRISPR-Cas9: Deletion, Integration, Single Nucleotide Modification, and Desirable "Clean" Mutant Selection in Clostridium beijerinckii as an Example.

  2016cited by this paper
• Cas13b is a Type VI-B CRISPR-associated RNA-Guided RNase differentially regulated by accessory proteins Csx27 and Csx28

  2016cited by this paper
• Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system

  2016cited by this paper
• Corrigendum: Hinge-like structure induced unusual properties of black phosphorus and new strategies to improve the thermoelectric performance

  2016cited by this paper
• CRISPR/Cas9 Based Genome Editing of Penicillium chrysogenum.

  2016cited by this paper
• Multiplex gene editing of the Yarrowia lipolytica genome using the CRISPR-Cas9 system

  2016cited by this paper
• Orthogonal Modular Gene Repression in Escherichia coli Using Engineered CRISPR/Cas9.

  2016cited by this paper
• Genome editing in Ustilago maydis using the CRISPR-Cas system.

  2016cited by this paper
• Structure and Engineering of Francisella novicida Cas9.

  2016cited by this paper
• Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris.

  2016cited by this paper
• Major bacterial lineages are essentially devoid of CRISPR-Cas viral defence systems

  2016cited by this paper
• Highly efficient CRISPR mutagenesis by microhomology-mediated end joining in Aspergillus fumigatus.

  2016cited by this paper
• Corynebacterium glutamicum Metabolic Engineering with CRISPR Interference (CRISPRi)

  2016cited by this paper
• CRISPR/Cas9-Based Efficient Genome Editing in Clostridium ljungdahlii, an Autotrophic Gas-Fermenting Bacterium.

  2016cited by this paper
• Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design

  2016cited by this paper
• Candida albicans Gene Deletion with a Transient CRISPR-Cas9 System

  2016cited by this paper
• Harnessing heterologous and endogenous CRISPR-Cas machineries for efficient markerless genome editing in Clostridium

  2016cited by this paper
• C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

  2016cited by this paper
• New CRISPR-Cas systems from uncultivated microbes

  2016cited by this paper
• Editing of the Bacillus subtilis Genome by the CRISPR-Cas9 System

  2016cited by this paper
• In vitro Characterization of Phenylacetate Decarboxylase, a Novel Enzyme Catalyzing Toluene Biosynthesis in an Anaerobic Microbial Community

  2016cited by this paper
• CRMAGE: CRISPR Optimized MAGE Recombineering

  2016cited by this paper
• Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in Escherichia coli

  2016cited by this paper
• Ancient DNA and the rewriting of human history: be sparing with Occam’s razor

  2016cited by this paper
• Genome editing of Clostridium autoethanogenum using CRISPR/Cas9

  2016cited by this paper
• Robust digital logic circuits in eukaryotic cells with CRISPR/dCas9 NOR gates

  2016cited by this paper
• rNA-guided editing of bacterial genomes using crisPr-cas systems

  2016cited by this paper
• Seamless site-directed mutagenesis of the Saccharomyces cerevisiae genome using CRISPR-Cas9

  2016cited by this paper
• Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae.

  2015cited by this paper
• CRISPR-Cas9 Based Engineering of Actinomycetal Genomes.

  2015cited by this paper
• Efficient Multiplexed Integration of Synergistic Alleles and Metabolic Pathways in Yeasts via CRISPR-Cas.

  2015cited by this paper
• Multigene Editing in the Escherichia coli Genome via the CRISPR-Cas9 System

  2015cited by this paper
• Discovery and Functional Characterization of Diverse Class 2 CRISPR-Cas Systems.

  2015cited by this paper
• Tailor‐made CRISPR/Cas system for highly efficient targeted gene replacement in the rice blast fungus

  2015cited by this paper
• Sensitive cells: enabling tools for static and dynamic control of microbial metabolic pathways.

  2015cited by this paper
• Harnessing CRISPR-Cas systems for bacterial genome editing.

  2015cited by this paper
• Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.

  2015cited by this paper
• Coupling the CRISPR/Cas9 System with Lambda Red Recombineering Enables Simplified Chromosomal Gene Replacement in Escherichia coli

  2015cited by this paper
• CrEdit: CRISPR mediated multi-loci gene integration in Saccharomyces cerevisiae

  2015cited by this paper
• An updated evolutionary classification of CRISPR–Cas systems

  2015cited by this paper
• CRISPR Diversity in E. coli Isolates from Australian Animals, Humans and Environmental Waters

  2015cited by this paper
• Efficient genome editing in filamentous fungus Trichoderma reesei using the CRISPR/Cas9 system

  2015cited by this paper
• Resource Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds

  2015cited by this paper
• A Candida albicans CRISPR system permits genetic engineering of essential genes and gene families

  2015cited by this paper
• Efficient gene editing in Neurospora crassa with CRISPR technology

  2015cited by this paper
• Temperate and lytic bacteriophages programmed to sensitize and kill antibiotic-resistant bacteria

  2015cited by this paper
• Interspecific and Geographic Variation in the Diets of Sympatric Carnivores: Dingoes/Wild Dogs and Red Foxes in South-Eastern Australia

  2015cited by this paper
• Targeted Large-Scale Deletion of Bacterial Genomes Using CRISPR-Nickases

  2015cited by this paper
• Efficient Genome Editing in Clostridium cellulolyticum via CRISPR-Cas9 Nickase

  2015cited by this paper
• Targeted DNA degradation using a CRISPR device stably carried in the host genome

  2015cited by this paper
• Homology-integrated CRISPR-Cas (HI-CRISPR) system for one-step multigene disruption in Saccharomyces cerevisiae.

  2015cited by this paper
• Development of a fed-batch process for a recombinant Pichia pastoris Δoch1 strain expressing a plant peroxidase

  2015cited by this paper
• A CRISPR-Cas9 System for Genetic Engineering of Filamentous Fungi

  2015cited by this paper
• Engineered CRISPR-Cas9 nucleases with altered PAM specificities

  2015cited by this paper
• CRISPR/Cas9: a molecular Swiss army knife for simultaneous introduction of multiple genetic modifications in Saccharomyces cerevisiae

  2015cited by this paper
• Markerless chromosomal gene deletion in Clostridium beijerinckii using CRISPR/Cas9 system.

  2015cited by this paper
• Development of a genome editing technique using the CRISPR/Cas9 system in the industrial filamentous fungus Aspergillus oryzae

  2015cited by this paper
• Large-scale profiling of microRNAs for The Cancer Genome Atlas

  2015cited by this paper
• Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

  2014cited by this paper
• Efficient programmable gene silencing by Cascade

  2014cited by this paper
• Advances in yeast genome engineering.

  2014cited by this paper
• Recovery of a Medieval Brucella melitensis Genome Using Shotgun Metagenomics

  2014cited by this paper
• Homologous recombination in human embryonic stem cells using CRISPR/Cas9 nickase and a long DNA donor template

  2014cited by this paper
• Selection of chromosomal DNA libraries using a multiplex CRISPR system

  2014cited by this paper
• Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity

  2014cited by this paper
• CRISPR–Cas systems: beyond adaptive immunity

  2014cited by this paper
• RNA targeting by the type III-A CRISPR-Cas Csm complex of Thermus thermophilus.

  2014cited by this paper
• Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

  2014cited by this paper
• CRISPR–Cas9-assisted recombineering in Lactobacillus reuteri

  2014cited by this paper
• Unravelling the structural and mechanistic basis of CRISPR–Cas systems

  2014cited by this paper
• Implementation of the CRISPR-Cas9 system in fission yeast

  2014cited by this paper
• Prospecting the biodiversity of the fungal family Ustilaginaceae for the production of value-added chemicals

  2014cited by this paper
• DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

  2014cited by this paper
• Development of sequence-specific antimicrobials based on programmable CRISPR-Cas nucleases

  2014cited by this paper
• High-Efficiency Multiplex Genome Editing of Streptomyces Species Using an Engineered CRISPR/Cas System

  2014cited by this paper
• Multi-input CRISPR/Cas genetic circuits that interface host regulatory networks

  2014cited by this paper
• Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

  2013cited by this paper
• Heritable genome editing in C. elegans via a CRISPR-Cas9 system

  2013cited by this paper
• Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk

  2013cited by this paper
• Multiplex Genome Engineering Using CRISPR/Cas Systems

  2013cited by this paper
• Cannabis and psychosis: what causes what?

  2013cited by this paper
• Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

  2013cited by this paper
• Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

  2013cited by this paper
• RNA-programmed genome editing in human cells

  2013cited by this paper
• In vitro reconstitution of Cascade‐mediated CRISPR immunity in Streptococcus thermophilus

  2013cited by this paper
• Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

  2013cited by this paper
• Editorial: NAR Surveys the Past, Present and Future of Restriction Endonucleases

  2013cited by this paper
• Control of gene expression by CRISPR-Cas systems

  2013cited by this paper
• Highly Efficient Targeted Mutagenesis of Drosophila with the CRISPR/Cas9 System

  2013cited by this paper
• CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes.

  2013cited by this paper
• One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.

  2013cited by this paper

• Resolving the Trade‐Off Between Toxicity and Efficiency of CRISPR‐Cas9 System for Genome Editing Within Escherichia coli

  2025cites this paper
• CRISPR/Cas systems for genomic Editing, biochemical Sensing, Bioanalysis, and diagnostics

  2025cites this paper
• Recent development in CRISPR-Cas systems for cardiac disease.

  2025cites this paper
• Current updates regarding biogenesis, functions and dysregulation of microRNAs in cancer: Innovative approaches for detection using CRISPR/Cas13-based platforms (Review)

  2025cites this paper
• Transforming non-conventional yeasts into key players in biotechnology: advances in synthetic biology applications

  2025cites this paper
• Enhancing Food Safety: Adapting to Microbial Responses Under Diverse Environmental Stressors

  2025cites this paper
• Integrating CRISPR/Cas technology with clinical trials: principles, progress, and challenges

  2025cites this paper
• CRISPR-Cas in the Cheese Industry.

  2025cites this paper
• Engineering of the Caspase-3 Gene in Recombinant CHO Cells Caused More Apoptosis Resistance and enhanced Recombinant Protein Production Than the BAX Gene

  2025cites this paper
• Design principle of successful genome editing applications using CRISPR-based toolkits

  2025cites this paper
• Epigenome Engineering Using dCas Systems for Biomedical Applications and Biotechnology: Current Achievements, Opportunities and Challenges

  2025cites this paper
• Exploring CRISPR/Cas9-Mediated Gene Editing Advances in Conventional and Non-conventional Yeast Species

  2025cites this paper
• Biosynthesis of Microbial Pigment-Mediated Nanoparticles and Its Biomedical Applications.

  2025cites this paper
• Exploration of Retron Elements for the Genetic Engineering of Acidithiobacillus ferrooxidans.

  2025cites this paper
• Bacillus and Streptomyces spp. as hosts for production of industrially relevant enzymes

  2024cites this paper
• Enhancing students’ digital skills through a Biotechnology & Bioprocessing module designed for chemical engineers

  2024cites this paper
• Innovative Biomedical and Technological Strategies for the Control of Bacterial Growth and Infections

  2024cites this paper
• Biology and applications of CRISPR–Cas12 and transposon-associated homologs

  2024cites this paper
• Signal amplified fluorometric detection of anti-CRISPR proteins based on rolling circle amplification

  2024cites this paper
• Optimizing Brassica oleracea L. Breeding Through Somatic Hybridization Using Cytoplasmic Male Sterility (CMS) Lines: From Protoplast Isolation to Plantlet Regeneration

  2024cites this paper
• Genetic Engineering in Bacteria, Fungi, and Oomycetes, Taking Advantage of CRISPR

  2024cites this paper
• Exploring the Role of CRISPR-Cas9 in Genetic Engineering: Advancements, Applications, and Ethical Issues

  2024influential citation
• CRISPR: New promising biotechnological tool in wastewater treatment.

  2024cites this paper
• The reverse genetic as a potential of virus‐induced gene silencing in tomato biology

  2024cites this paper
• Efficient Metabolic Pathway Modification in Various Strains of Lactic Acid Bacteria using CRISPR/Cas9 System for elevated synthesis of Antimicrobial Compounds.

  2024cites this paper
• Current application and future perspective of CRISPR/cas9 gene editing system mediated immune checkpoint for liver cancer treatment

  2024cites this paper
• CRISPR-Cas9-based genome-editing technologies in engineering bacteria for the production of plant-derived terpenoids

  2024cites this paper
• Rapidly engineering an osmotic-pressure-tolerant gut bacterium for efficient non-sterile production of bulk chemicals

  2024cites this paper
• Biomaterial-Based CRISPR/Cas9 Delivery Systems for Tumor Treatment.

  2024cites this paper
• Future-Proofing Agriculture: De Novo Domestication for Sustainable and Resilient Crops

  2024cites this paper
• Biotechnological interventions of improvement in cabbage (Brassica oleracea var. capitata L.)

  2024cites this paper
• CRISPR-Cas Technology for Bioengineering Conventional and Non-Conventional Yeasts: Progress and New Challenges

  2023cites this paper
• CRISPR/Cas9 System-Mediated Multi-copy Expression of an Alkaline Serine Protease in Aspergillus niger for the Production of XOD-Inhibitory Peptides.

  2023cites this paper
• Synthetic phage and its application in phage therapy.

  2023cites this paper
• Endogenous CRISPR-Cas mediated in situ genome editing: State-of-the-art and the road ahead for engineering prokaryotes.

  2023cites this paper
• Development of a CRISPR/Cpf1 system for multiplex gene editing in Aspergillus oryzae

  2023cites this paper
• Efficient CRISPR/Cas9-Mediated BAX Gene Ablation in CHO Cells To Impair Apoptosis and Enhance Recombinant Protein Production

  2023cites this paper
• Significance and genetic control of membrane transporters to improve phytoremediation and biofortification processes

  2023cites this paper
• CRISPR-Cas System: The Current and Emerging Translational Landscape

  2023cites this paper
• The CRISPR technology: A promising strategy for improving dark fermentative biohydrogen production using Clostridium spp.

  2023cites this paper
• The use of CRISPR-Cas-based systems in bacterial cell factories

  2023cites this paper
• Recent progress in pervaporation membranes for furfural recovery: A mini review

  2023cites this paper
• The genome editing revolution.

  2023cites this paper
• CRISPR-Cas engineering in food science and sustainable agriculture: recent advancements and applications

  2023cites this paper
• CRISPR enables sustainable cereal production for a greener future.

  2023cites this paper
• Production of Amino Acids and Nucleic Acids from Genetically Engineered Microbial Cells and their Relevance to Biodegradation

  2023cites this paper
• Synergistic investigation of natural and synthetic C1-trophic microorganisms to foster a circular carbon economy

  2023cites this paper
• Engineering to enhance thermostability of xylanase: For the new era of biotechnology

  2022cites this paper
• CRISPR ERA: Current Applications and Future Perspectives on Actinobacteria

  2022cites this paper
• Recent advances in the development of Aspergillus for protein production.

  2022cites this paper
• Drug-food Interactions in the Era of Molecular Big Data, Machine Intelligence, and Personalized Health

  2022cites this paper
• CRISPR/Cas9 technology as an innovative approach to enhancing the phytoremediation: Concepts and implications.

  2022cites this paper
• The CRISPR/Cas Machinery Evolution and Gene Flow in the Hot Spring Cyanobacterium Thermostichus

  2022cites this paper
• Polydimethylsiloxane based membranes for biofuels pervaporation

  2022cites this paper
• Genome Editing Targets for Improving Nutrient Use Efficiency and Nutrient Stress Adaptation

  2022cites this paper
• Modular (de)construction of complex bacterial phenotypes by CRISPR/nCas9-assisted, multiplex cytidine base-editing

  2022cites this paper
• Construction of single, double, or triple mutants within kojic acid synthesis genes kojA, kojR, and kojT by the CRISPR/Cas9 tool in Aspergillus oryzae

  2022cites this paper
• Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans

  2022cites this paper
• Saccharomyces cerevisiae as a Heterologous Host for Natural Products.

  2022cites this paper
• Distribution, molecular evolution, and mutational scanning of the anti- CRISPR family AcrIF7 reveal conservation, key residues for the protein function and a putative alternative binding mode to Cas8f

  2022cites this paper
• Genetic physical unclonable functions in human cells

  2022cites this paper
• CRISPR/Cas genome editing systems in thermophiles: Current status, associated challenges, and future perspectives.

  2022cites this paper
• Design and construction of microbial cell factories based on systems biology

  2022cites this paper
• Distribution and molecular evolution of the anti-CRISPR family AcrIF7

  2022cites this paper
• Microfluidics in Biotechnology: Overview and Status Quo.

  2022cites this paper
• Frankenstein Cas9: engineering improved gene editing systems.

  2022cites this paper
• CRISPR-Cas system in microbial hosts for terpenoid production

  2022cites this paper
• High-Efficiency Genome Editing Based on Endogenous CRISPR-Cas System Enhances Cell Growth and Lactic Acid Production in Pediococcus acidilactici

  2021cites this paper
• Functional Identification of the Xanthomonas oryzae pv. oryzae Type I-C CRISPR-Cas System and Its Potential in Gene Editing Application

  2021cites this paper
• CRISPRclassify: Repeat-Based Classification of CRISPR Loci

  2021cites this paper
• Harnessing the CRISPR-Cas Systems to Combat Antimicrobial Resistance

  2021cites this paper
• CRISPR-Cas9 Gene Editing for Fruit and Vegetable Crops: Strategies and Prospects

  2021cites this paper
• Non-Conventional Yeasts as Alternatives in Modern Baking for Improved Performance and Aroma Enhancement

  2021cites this paper
• CRISPR–Cas systems in bioactive peptide research

  2021cites this paper
• CRISPR/Cas 9-Based Editing in the Production of Bioactive Molecules

  2021cites this paper
• A Novel and Efficient Genome Editing Tool Assisted by CRISPR-Cas12a/Cpf1 for Pichia pastoris.

  2021cites this paper
• CRISPR-Cas Genome Editing in the Cellulolytic Bacterium Clostridium thermocellum (C. thermocellum)

  2021cites this paper
• Predicting Targets for Genome Editing with Long Short Term Memory Networks

  2021cites this paper
• Endogenous CRISPR-assisted microhomology-mediated end joining enables rapid genome editing in Zymomonas mobilis

  2021cites this paper
• Computational Approaches for Designing Highly Specific and Efficient sgRNAs.

  2021cites this paper
• Recent advancements on use of CRISPR /Cas9 in maize yield and quality improvement

  2021cites this paper
• Controlling pathogenic risks of water treatment biotechnologies at the source by genetic editing means.

  2021cites this paper
• Development of a CRISPR interference system for selective gene knockdown in Acidithiobacillus ferrooxidans.

  2021cites this paper
• Feeding the Future—Challenges and Limitations

  2021cites this paper
• Current state and future prospects of pure mycelium materials

  2021cites this paper
• CRISPR/Cas9: Contemporary designer nucleases for efficient genome editing in phytopathogenic fungi

  2021influential citation
• Trichoderma reesei: Methods and Protocols

  2021cites this paper
• Resistance Marker- and Gene Gun-Mediated Transformation of Trichoderma reesei.

  2021cites this paper
• CRISPR-Based Genetic Manipulation of Candida Species: Historical Perspectives and Current Approaches

  2021cites this paper
• CRISPR-ENHANCE: An enhanced nucleic acid detection platform using Cas12a.

  2021cites this paper
• Bioremediation of lignin derivatives and phenolics in wastewater with lignin modifying enzymes: Status, opportunities and challenges.

  2021cites this paper
• Genetically Intact Bioengineered Spores of Bacillus subtilis.

  2021cites this paper
• Novel CRISPR–Cas Systems: An Updated Review of the Current Achievements, Applications, and Future Research Perspectives

  2021cites this paper
• Patents and technology transfer in CRISPR technology.

  2021cites this paper
• CRISPR-based tools for microbial cell factories

  2021cites this paper
• Phage satellites and their emerging applications in biotechnology.

  2021cites this paper
• Provenance Attestation of Human Cells Using Physical Unclonable Functions

  2021cites this paper
• Improving rice eating and cooking quality by coordinated expression of the major starch synthesis-related genes, SSII and Wx, in endosperm

  2021cites this paper
• Molecular evolution of the anti-CRISPR family AcrIF7 reveals conservation despite mutation tolerance

  2021cites this paper
• A highly efficient identification of mutants generated by CRISPR/Cas9 using the non‑functional DsRed assisted selection in Aspergillus oryzae

  2021cites this paper