The signal transducer and activator of transcription STAT5b gene is a new partner of retinoic acid receptor alpha in acute promyelocytic-like leukaemia.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Human Molecular Genetics

• Publication date

  1999-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/HMG/8.9.1741PMID 10441338
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Termination of growth hormone pulse-induced STAT5b signaling.

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• Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells.

  1999cited by this paper
• Functional Association of Nmi with Stat5 and Stat1 in IL-2- and IFN γ-Mediated Signaling

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• A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation.

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• Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.

  1998cited by this paper
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  1998cited by this paper
• Carboxyl-Truncated STAT5β Is Generated by a Nucleus-Associated Serine Protease in Early Hematopoietic Progenitors

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• SMRT corepressor interacts with PLZF and with the PML-retinoic acid receptor alpha (RARalpha) and PLZF-RARalpha oncoproteins associated with acute promyelocytic leukemia.

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• Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype

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