Leptin and reproduction.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Human Reproduction Update

• Publication date

  2000-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/HUMUPD/6.3.290PMID 10874574
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Brain administration of leptin causes deletion of adipocytes by apoptosis.

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• Human leptin forms complexes with alpha 2-macroglobulin which are recognized by the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein.

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• Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone.

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• Serum Leptin Concentrations During Pregnancy and Their Relationship to Fetal Growth

  1998cited by this paper
• Concentrations of leptin in the serum of pregnant, lactating, and cycling rats and of leptin messenger ribonucleic acid in rat placental tissue.

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  1998cited by this paper
• Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice.

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• Leptin is not necessary for gestation and parturition but regulates maternal nutrition via a leptin resistance state.

  1998cited by this paper
• A leptin missense mutation associated with hypogonadism and morbid obesity

  1998cited by this paper
• Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: dexamethasone and estradiol stimulate leptin release in women, but not in men.

  1998cited by this paper
• Decreased leptin levels in normal weight women with hypothalamic amenorrhea: the effects of body composition and nutritional intake.

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• Is there a role for leptin in human reproduction?

  1998cited by this paper
• Adipose obese gene product, leptin, inhibits bovine ovarian thecal cell steroidogenesis.

  1998cited by this paper
• In Vivo and in Vitro Evidence for the Involvement of Tumor Necrosis Factor-α in the Induction of Leptin by Lipopolysaccharide.

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• Autocrine Inhibition of Leptin Production by Tumor Necrosis Factor-α (TNF-α) through TNF-α Type-I Receptorin Vitro☆

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• In vivo and in vitro evidence for the involvement of tumor necrosis factor-alpha in the induction of leptin by lipopolysaccharide.

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• The stimulatory effect of leptin on the neuroendocrine reproductive axis of the monkey.

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• The Leptin Receptor*

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• Leptin accelerates the onset of puberty in normal female mice.

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• Depot- and Sex-Specific Differences in Human Leptin mRNA Expression: Implications for the Control of Regional Fat Distribution

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  1997cited by this paper
• Direct Intraovarian Effects of Leptin: Impairment of the Synergistic Action of Insulin-Like Growth Factor-I on Follicle-Stimulating Hormone-Dependent Estradiol-17β Production by Rat Ovarian Granulosa Cells.

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• Embryonic Regulation of Integrins β3,α 4, and α1 in Human Endometrial Epithelial Cells in Vitro1

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  1997cited by this paper
• Identification of the human leptin 5'-flanking sequences involved in the trophoblast-specific transcription.

  1997cited by this paper
• Multiple Cytokines and Acute Inflammation Raise Mouse Leptin Levels: Potential Role in Inflammatory Anorexia

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• Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats.

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• Transforming Growth Factor-β Enhances and Pro-inflammatory Cytokines Inhibit OB Gene Expression in 3T3-L1 Adipocytes

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• Depot- and sex-specific differences in human leptin mRNA expression: implications for the control of regional fat distribution.

  1997cited by this paper
• Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo.

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• Leptin is a four‐helix bundle: secondary structure by NMR

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• Placental Leptin: An Important New Growth Factor in Intrauterine and Neonatal Development? † 1379

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• Leptin: a hormone of reproduction.

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• The leptin receptor mediates apparent autocrine regulation of leptin gene expression.

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• Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality.

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• Interleukin 1 alpha increases serum leptin concentrations in humans.

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• Gestational exposure to TDCIPP disrupts embryonic development via LEPR-mediated IL6/JAK2/STAT3 signaling pathway in mice.

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  2024cites this paper
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  2024cites this paper
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• Excessive Pregestational Weight and Maternal Obstetric Complications: The Role of Adipokines

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• Journal of Reproduction and Development

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• Leptin effects: focusing on the relationship between obesity and male infertility.

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• Are the body shape index, the body roundness index and waist‐to‐hip ratio better than BMI to predict recurrent pregnancy loss?

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  2020cites this paper
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  2018cites this paper
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