Liver fibrosis is the result of the entire organism responding to a chronic injury. Every cell type in the liver contributes to the fibrosis. This paper first discusses key intracellular signaling pathways that are induced during liver fibrosis. The paper then examines the effects of these signaling pathways on the major cell types in the liver. This will provide insights into the molecular pathophysiology of liver fibrosis and should identify therapeutic targets.
Cell Signals Influencing Hepatic Fibrosis
M. Cong,K. Iwaisako,Chunyan Jiang,T. Kisseleva
Published 2012 in International Journal of Hepatology
ABSTRACT
PUBLICATION RECORD
- Publication year
2012
- Venue
International Journal of Hepatology
- Publication date
2012-08-29
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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