Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Development

• Publication date

  2012-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/dev.073759PMID 22159581PMCID PMC3243095
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010influential reference
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