Analysis of ToxR‐dependent transcription activation of ompU, the gene encoding a major envelope protein in Vibrio cholerae

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Molecular Microbiology

• Publication date

  1998-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1365-2958.1998.00925.xPMID 9701817
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bile salts and fatty acids induce the expression of Escherichia coli AcrAB multidrug efflux pump through their interaction with Rob regulatory protein

  2003cited by this paper
• TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae.

  1998cited by this paper
• Identification of a regulatory protein required for pressure‐responsive gene expression in the deep‐sea bacterium Photobacterium species strain SS9

  1998cited by this paper
• Phase variation in tcpH modulates expression of the ToxR regulon in Vibrio cholerae

  1997influential reference
• The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor.

  1997cited by this paper
• Nature of DNA binding and RNA polymerase interaction of the Bordetella pertussis BvgA transcriptional activator at the fha promoter

  1997cited by this paper
• A branch in the ToxR regulatory cascade of Vibrio cholerae revealed by characterization of toxT mutant strains

  1997influential reference
• Transcriptional regulation of the Yersinia pseudotuberculosis pH 6 antigen adhesin by two envelope‐associated components

  1997cited by this paper
• Lysogenic Conversion by a Filamentous Phage Encoding Cholera Toxin

  1996influential reference
• Porins of Vibrio cholerae: purification and characterization of OmpU

  1996cited by this paper
• Differential expression of the ToxR regulon in classical and E1 Tor biotypes of Vibrio cholerae is due to biotype-specific control over toxT expression.

  1996cited by this paper
• Genetic analysis of the interaction between Vibrio cholerae transcription activator ToxR and toxT promoter DNA

  1996cited by this paper
• A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae.

  1996cited by this paper
• Identification of the bases in the ompF regulatory region, which interact with the transcription factor OmpR.

  1996cited by this paper
• Cloning and characterization of the gene encoding the OmpU outer membrane protein of Vibrio cholerae

  1996influential reference
• Genetic footprint of the ToxR‐binding site in the promoter for cholera toxin

  1996influential reference
• The OmpU outer membrane protein, a potential adherence factor of Vibrio cholerae

  1995cited by this paper
• Identification of base pairs important for OmpR‐DNA interaction

  1995cited by this paper
• Synergistic binding of RNA polymerase and BvgA phosphate to the pertussis toxin promoter of Bordetella pertussis

  1995cited by this paper
• Organization of tcp, acf, and toxT genes within a ToxT‐dependent operon

  1995cited by this paper
• Isolation and characterization of the Vibrio cholerae acfA gene, required for efficient intestinal colonization.

  1995cited by this paper
• The light organ symbiont Vibrio fischeri possesses a homolog of the Vibrio cholerae transmembrane transcriptional activator ToxR

  1994cited by this paper
• The Vibrio cholerae acfB colonization determinant encodes an inner membrane protein that is related to a family of signal-transducing proteins

  1994cited by this paper
• Analysis of membrane protein interaction: ToxR can dimerize the amino terminus of phage lambda repressor

  1994cited by this paper
• DNA recognition by DNase I

  1994cited by this paper
• Roles of LysP and CadC in mediating the lysine requirement for acid induction of the Escherichia coli cad operon

  1994cited by this paper
• Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae

  1994influential reference
• Sequence elements responsible for DNA curvature.

  1994cited by this paper
• Sequence analysis of the Vibrio cholerae acfD gene reveals the presence of an overlapping reading frame, orfZ, which encodes a protein that shares sequence similarity to the FliA and FliC products of Salmonella.

  1994cited by this paper
• Vibrio parahaemolyticus has a homolog of the Vibrio cholerae toxRS operon that mediates environmentally induced regulation of the thermostable direct hemolysin gene

  1993cited by this paper
• ToxR proteins with substitutions in residues conserved with OmpR fail to activate transcription from the cholera toxin promoter

  1992cited by this paper
• The virulence gene activator ToxT from Vibrio cholerae is a member of the AraC family of transcriptional activators

  1992cited by this paper
• Co‐ordinate expression of virulence genes by ToxR in Vibrio cholerae

  1992cited by this paper
• A method for constructing single-copy lac fusions in Salmonella typhimurium and its application to the hemA-prfA operon

  1992influential reference
• Type 1 fimbriae mutants of Escherichia coli K12: characterization of recognized afimbriate strains and construction of new fim deletion mutants

  1991cited by this paper
• Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation.

  1991influential reference
• Regulatory cascade controls virulence in Vibrio cholerae.

  1991influential reference
• Improved vector system for constructing transcriptional fusions that ensures independent translation of lacZ

  1990cited by this paper
• Characterization of the Vibrio cholerae ToxR Regulon: Identification of Novel Genes Involved in Intestinal Colonization

  1989cited by this paper
• Identification of toxS, a regulatory gene whose product enhances toxR-mediated activation of the cholera toxin promoter

  1989influential reference
• A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR

  1988cited by this paper
• Toxin, toxin-coregulated pili, and the toxR regulon are essential for Vibrio cholerae pathogenesis in humans

  1988cited by this paper
• Improved single and multicopy lac-based cloning vectors for protein and operon fusions.

  1987cited by this paper
• Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxin.

  1987influential reference
• Cholera toxin transcriptional activator toxR is a transmembrane DNA binding protein.

  1987influential reference
• Synthesis of cholera toxin is positively regulated at the transcriptional level by toxR.

  1984cited by this paper
• Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

  1978cited by this paper
• Experiments in molecular genetics

  1972influential reference

• Crystal structure of the V. parahaemolyticus ToxS dimer suggests a model for bile-induced ToxRS activation

  2026cites this paper
• Structures of Vibrio cholerae transcription complexes reveal how ToxR and TcpP recruit the RNA polymerase and activate virulence genes

  2026cites this paper
• Functional Versatility of Vibrio cholerae Outer Membrane Proteins

  2025cites this paper
• Vibrio cholerae CsrA controls ToxR levels by increasing the stability and translation of toxR mRNA

  2024cites this paper
• Vibrio cholerae’s ToxRS bile sensing system

  2023cites this paper
• ToxR activates the Vibrio cholerae virulence genes by tethering DNA to the membrane through versatile binding to multiple sites

  2023cites this paper
• Modular small RNA drives pathogen emergence

  2023cites this paper
• Structural Insights into Regulation of Vibrio Virulence Gene Networks.

  2023cites this paper
• Cholera Dynamics and the Emergence of Pandemic Vibrio cholerae.

  2023cites this paper
• Identification and characterization of Aeromonas veronii and Vibrio cholerae from naturally diseased red swamp crayfish (Procambarus clarkia)

  2023cites this paper
• Molecular mechanisms and drivers of pathogen emergence.

  2022cites this paper
• Identification of Potent Natural Resource Small Molecule Inhibitor to Control Vibrio cholera by Targeting Its Outer Membrane Protein U: An In Silico Approach

  2021cites this paper
• Structure, regulation, and host interaction of outer membrane protein U (OmpU) of Vibrio species.

  2021cites this paper
• Structural and DNA-binding properties of the cytoplasmic domain of Vibrio cholerae transcription factor ToxR

  2021cites this paper
• Vibrio cholerae TolC Is Required for Expression of the ToxR Regulon

  2021cites this paper
• The periplasmic domains of Vibriocholerae ToxR and ToxS are forming a strong heterodimeric complex independent on the redox state of ToxR cysteines

  2020cites this paper
• Structural and Functional Changes in the Genome of Avirulent El Tor Biovar Vibrio choleraectxA+tcpA+ Strains

  2020cites this paper
• A disulfide constrains the ToxR periplasmic domain structure, altering its interactions with ToxS and bile-salts

  2020cites this paper
• Host stimuli and operator binding sites controlling protein interactions between virulence master regulator ToxR and ToxS in Vibrio cholerae

  2020cites this paper
• Vibrio cholerae OmpR Contributes to Virulence Repression and Fitness at Alkaline pH

  2020cites this paper
• Structural and functional changes of the genome in avirulent Vibrio cholerae strains biovar El Tor, genotype ctxA+tcpA+

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  2019cites this paper
• The wing of the ToxR winged helix-turn-helix domain is required for DNA binding and activation of toxT and ompU

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Multiple intraintestinal signals coordinate the regulation of Vibrio cholerae virulence determinants.

  2018cites this paper
• Biochemical basis for activation of virulence genes by bile salts in Vibrio parahaemolyticus

  2017cites this paper
• Bile salts and alkaline pH reciprocally modulate the interaction between the periplasmic domains of Vibrio cholerae ToxR and ToxS

  2017cites this paper
• The Vibrio cholerae Stress Response: An Elaborate System Geared Toward Overcoming Host Defenses During Infection

  2016cites this paper
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  2016cites this paper
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  2015cites this paper
• Chapter 60 – Vibrio cholerae

  2015cites this paper
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  2015cites this paper
• Vibrio cholerae leuO Transcription Is Positively Regulated by ToxR and Contributes to Bile Resistance

  2015cites this paper
• Vibrio cholerae Porin OmpU Induces Caspase-independent Programmed Cell Death upon Translocation to the Host Cell Mitochondria*

  2015cites this paper
• The Cpx System Regulates Virulence Gene Expression in Vibrio cholerae

  2015cites this paper
• Vibrio cholerae porin OmpU induces LPS tolerance by attenuating TLR-mediated signaling.

  2015cites this paper
• Role of ToxS in the proteolytic cascade of virulence regulator ToxR in Vibrio cholerae

  2015cites this paper
• Chromosome Segregation Proteins of Vibrio cholerae as Transcription Regulators

  2014cites this paper
• Differential induction isolation physicochemical and molecular characterization of temperate phages of environmental Vibrio cholerae as evidence of phage mediated Horizontal Gene Transfer

  2014cites this paper
• OmpU as a biomarker for rapid discrimination between toxigenic and epidemic Vibrio cholerae O1/O139 and non-epidemic Vibrio cholerae in a modified MALDI-TOF MS assay

  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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• Disulfide Bond Formation and ToxR Activity in Vibrio cholerae

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• Effects of Amino Acid Supplementation on Porin Expression and ToxR Levels in Vibrio cholerae

  2011cites this paper
• The two faces of ToxR: activator of ompU, co‐regulator of toxT in Vibrio cholerae

  2011influential citation
• Estudio de la funcionalidad de ToxR en cepas atenuadas de Vibrio cholerae O139

  2011cites this paper
• Estudio de la funcionalidad de ToxR en cepas atenuadas de Vibrio cholerae O139

  2011cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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  2007cites this paper
• Generación de hibridomas productores de anticuerpos monoclonales contra la proteína de membrana externa U (OmpU) de Vibrio cholerae

  2007cites this paper
• Modulation of Vibrio cholerae Porin Function by Acidic pH

  2007cites this paper
• Effects of Vibrio cholerae protease and pigment production on environmental survival and host interaction

  2007cites this paper
• Phenotypic Characterization of Pore Mutants of the Vibrio cholerae Porin OmpU

  2007cites this paper
• Regulation of virulence in Vibrio cholerae: the ToxR regulon.

  2007cites this paper
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  2007cites this paper
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