Model-based biotechnological potential analysis of Kluyveromyces marxianus central metabolism

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Industrial Microbiology & Biotechnology

• Publication date

  2017-04-25

• Fields of study

  Biology, Chemistry, Engineering, Environmental Science, Medicine

• Identifiers
  DOI 10.1007/s10295-017-1946-8PMID 28444480
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Model-based metabolism design: constraints for kinetic and stoichiometric models

  2018cited by this paper
• Effect of Evolutionary Adaption on Xylosidase Activity in Thermotolerant Yeast Isolates Kluyveromyces marxianus NIRE-K1 and NIRE-K3

  2016cited by this paper
• Enhancement in xylose utilization using Kluyveromyces marxianus NIRE-K1 through evolutionary adaptation approach

  2016cited by this paper
• Effects of acetate on Kluyveromyces marxianus DSM 5422 growth and metabolism

  2016cited by this paper
• Simultaneous fermentation of glucose and xylose at elevated temperatures co-produces ethanol and xylitol through overexpression of a xylose-specific transporter in engineered Kluyveromyces marxianus.

  2016cited by this paper
• Efficient conversion of xylose to ethanol by stress-tolerant Kluyveromyces marxianus BUNL-21

  2016cited by this paper
• Modeling of exo-inulinase biosynthesis by Kluyveromyces marxianus in fed-batch mode: correlating production kinetics and metabolic heat fluxes

  2016cited by this paper
• Metabolic Engineering Principles And Methodologies

  2016cited by this paper
• Kluyveromyces marxianus as a host for heterologous protein synthesis

  2016cited by this paper
• Growth, ethanol production, and inulinase activity on various inulin substrates by mutant Kluyveromyces marxianus strains NRRL Y-50798 and NRRL Y-50799

  2016cited by this paper
• Utilisation of sugar beet bagasse for the biosynthesis of yeast SCP

  2015cited by this paper
• Genetic basis of the highly efficient yeast Kluyveromyces marxianus: complete genome sequence and transcriptome analyses

  2015cited by this paper
• Complete Genome Sequence of Kluyveromyces marxianus NBRC1777, a Nonconventional Thermotolerant Yeast

  2015cited by this paper
• Improving xylitol production at elevated temperature with engineered Kluyveromyces marxianus through over-expressing transporters.

  2015cited by this paper
• Rapid ethanol production at elevated temperatures by engineered thermotolerant Kluyveromyces marxianus via the NADP(H)-preferring xylose reductase-xylitol dehydrogenase pathway.

  2015cited by this paper
• Cell factory applications of the yeast Kluyveromyces marxianus for the biotechnological production of natural flavour and fragrance molecules

  2015cited by this paper
• Transcriptional analysis of Kluyveromyces marxianus for ethanol production from inulin using consolidated bioprocessing technology

  2015cited by this paper
• Enhanced Xylitol Production by Mutant Kluyveromyces marxianus 36907-FMEL1 Due to Improved Xylose Reductase Activity

  2015cited by this paper
• The modeling of ethanol production by Kluyveromyces marxianus using whey as substrate in continuous A-Stat bioreactors

  2015cited by this paper
• Optimizing promoters and secretory signal sequences for producing ethanol from inulin by recombinant Saccharomyces cerevisiae carrying Kluyveromyces marxianus inulinase

  2015cited by this paper
• Studies on the mechanism of synthesis of ethyl acetate in Kluyveromyces marxianus DSM 5422

  2015cited by this paper
• Xylitol production at high temperature by engineered Kluyveromyces marxianus.

  2014cited by this paper
• Applications of computational modeling in metabolic engineering of yeast.

  2014cited by this paper
• Modeling of Zymomonas mobilis central metabolism for novel metabolic engineering strategies

  2014cited by this paper
• Effect of oxygenation and temperature on glucose-xylose fermentation in Kluyveromyces marxianus CBS712 strain

  2014influential reference
• A biosynthetic pathway for hexanoic acid production in Kluyveromyces marxianus.

  2014cited by this paper
• iOD907, the first genome-scale metabolic model for the milk yeast Kluyveromyces lactis.

  2014cited by this paper
• Growth and by‐product profiles of Kluyveromyces marxianus cells immobilized in foamed alginate

  2014cited by this paper
• Biosynthesis of 2-phenylethanol from glucose with genetically engineered Kluyveromyces marxianus.

  2014cited by this paper
• Succinic acid production derived from carbohydrates: An energy and greenhouse gas assessment of a platform chemical toward a bio‐based economy

  2014cited by this paper
• Growth of the yeast Kluyveromyces marxianus CBS 6556 on different sugar combinations as sole carbon and energy source

  2013cited by this paper
• Glycolic acid production in the engineered yeasts Saccharomyces cerevisiae and Kluyveromyces lactis

  2013cited by this paper
• Improved ethanol production in Jerusalem artichoke tubers by overexpression of inulinase gene in Kluyveromyces marxianus

  2013cited by this paper
• Formation of ethyl acetate by Kluyveromyces marxianus on whey: Influence of aeration and inhibition of yeast growth by ethyl acetate

  2013cited by this paper
• Rapid phosphatidic acid accumulation in response to low temperature stress in Arabidopsis is generated through diacylglycerol kinase

  2013cited by this paper
• Multifunctional fructans and raffinose family oligosaccharides

  2013cited by this paper
• Essentiality of respiratory activity for pentose utilization in thermotolerant yeast Kluyveromyces marxianus DMKU 3-1042

  2013cited by this paper
• Formation of ethyl acetate from whey by Kluyveromyces marxianus on a pilot scale.

  2013cited by this paper
• Biotechnological potential of respiring Zymomonas mobilis: a stoichiometric analysis of its central metabolism.

  2013cited by this paper
• Biotechnological approaches for the value addition of whey

  2012cited by this paper
• A sustainable woody biomass biorefinery.

  2012cited by this paper
• GenBank

  2012cited by this paper
• Formation of ethyl acetate by Kluyveromyces marxianus on whey during aerobic batch cultivation at specific trace element limitation

  2012cited by this paper
• OGEE: an online gene essentiality database

  2011cited by this paper
• A biochemically structured model for ethanol fermentation by Kluyveromyces marxianus: A batch fermentation and kinetic study.

  2011cited by this paper
• UniProt Knowledgebase: a hub of integrated protein data

  2011cited by this paper
• PubChem's BioAssay Database

  2011cited by this paper
• Biotechnological potential of inulin for bioprocesses.

  2011cited by this paper
• Identification of a xylose reductase gene in the xylose metabolic pathway of Kluyveromyces marxianus NBRC1777

  2011cited by this paper
• Transport of dicarboxylates in Saccharomyces cerevisiae

  2011cited by this paper
• From lactic acid to poly(lactic acid) (PLA): characterization and analysis of PLA and its precursors.

  2011cited by this paper
• In Silico Study of Aro Genes Involved in the Ehrlich Pathway: Comparison between Saccharomyces Cerevisiae and Kluyveromyces Lactis

  2011cited by this paper
• The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

  2011cited by this paper
• Rational design and construction of an efficient E. coli for production of diapolycopendioic acid.

  2010cited by this paper
• Building and analysing genome-scale metabolic models.

  2010cited by this paper
• What is flux balance analysis?

  2010influential reference
• Glutamate. Its applications in food and contribution to health.

  2010cited by this paper
• Kluyveromyces marxianus: A yeast emerging from its sister's shadow

  2010cited by this paper
• Limitations in Xylose-Fermenting Saccharomyces cerevisiae, Made Evident through Comprehensive Metabolite Profiling and Thermodynamic Analysis

  2010cited by this paper
• Identification and Functional Characterization of a Novel Mitochondrial Carrier for Citrate and Oxoglutarate in Saccharomyces cerevisiae*

  2010cited by this paper
• Validation of a constraint-based model of Pichia pastoris metabolism under data scarcity

  2010cited by this paper
• Metabolic engineering of Saccharomyces cerevisiae for the biotechnological production of succinic acid.

  2010influential reference
• A protocol for generating a high-quality genome-scale metabolic reconstruction

  2010cited by this paper
• The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

  2009cited by this paper
• The oxygen level determines the fermentation pattern in Kluyveromyces lactis.

  2009cited by this paper
• The malate-aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restriction-mediated life span extension in yeast.

  2008cited by this paper
• NCBI BLAST: a better web interface

  2008cited by this paper
• Minimal Escherichia coli Cell for the Most Efficient Production of Ethanol from Hexoses and Pentoses

  2008cited by this paper
• The yeast Kluyveromyces marxianus and its biotechnological potential

  2008cited by this paper
• Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

  2007cited by this paper
• ChEBI: a database and ontology for chemical entities of biological interest

  2007cited by this paper
• Bioconversion of l-phenylalanine into 2-phenylethanol by Kluyveromyces marxianus in grape must cultures

  2007cited by this paper
• Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox

  2007influential reference
• Sequential gene integration for the engineering of Kluyveromyces marxianus.

  2007cited by this paper
• ScrumPy: metabolic modelling with Python.

  2006cited by this paper
• Use of cell recycle in the aerobic fermentative production of citric acid by yeast

  2005cited by this paper
• A growth kinetic model of Kluyveromyces marxianus cultures on cheese whey as substrate

  2004cited by this paper
• The Deletion of the Succinate Dehydrogenase Gene KlSDH1 in Kluyveromyces lactis Does Not Lead to Respiratory Deficiency

  2004cited by this paper
• IntEnz, the integrated relational enzyme database

  2004influential reference
• Top Value Added Chemicals From Biomass. Volume 1 - Results of Screening for Potential Candidates From Sugars and Synthesis Gas

  2004cited by this paper
• The effects of alternate optimal solutions in constraint-based genome-scale metabolic models.

  2003influential reference
• The acetyl co‐enzyme A synthetase genes of Kluyveromyces lactis

  2003cited by this paper
• The NADP+-dependent glutamate dehydrogenase of the yeast Kluyveromyces marxianus responds to nitrogen repression similarly to Saccharomyces cerevisiae

  2003cited by this paper
• Screening of yeasts for the production of the aroma compound 2-phenylethanol in a molasses-based medium

  2003cited by this paper
• D-Xylose transport by Candida succiphila and Kluyveromyces marxianus.

  2003cited by this paper
• The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

  2003cited by this paper
• Metabolic flux analysis of xylose metabolism in recombinant Saccharomyces cerevisiae using continuous culture.

  2003cited by this paper
• Inhibition aspects of the bioconversion of l-phenylalanine to 2-phenylethanol by Saccharomyces cerevisiae

  2003cited by this paper
• d-xylose transport by Candida succiphila and Kluyveromyces marxianus

  2003cited by this paper
• Metabolic physiology of aroma‐producing Kluyveromyces marxianus

  2002cited by this paper
• Functional profiling of the Saccharomyces cerevisiae genome

  2002cited by this paper
• Biotechnological production of 2-phenylethanol

  2002cited by this paper
• Efficient Homolactic Fermentation byKluyveromyces lactis Strains Defective in Pyruvate Utilization and Transformed with the HeterologousLDH Gene

  2001cited by this paper
• Network Identification and Flux Quantification in the Central Metabolism of Saccharomyces cerevisiae under Different Conditions of Glucose Repression

  2001cited by this paper
• A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks

  2000cited by this paper
• Pathways for glutamate biosynthesis in the yeast Kluyveromyces lactis.

  2000cited by this paper
• Replacement of a Metabolic Pathway for Large-Scale Production of Lactic Acid from Engineered Yeasts

  1999cited by this paper
• Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.

  1999cited by this paper
• Metabolite transport in isolated yeast mitochondria: fumarate/malate and succinate/malate antiports

  1999cited by this paper
• Control of specific growth rate and physiology of the yeast Kluyveromyces marxianus. A BioThermoKinetic approach.

  1999cited by this paper

• Efficient 2G Ethanol Production via Optimized Dilute Acid Pretreatment, High-Solids Enzymatic Hydrolysis, and High-Temperature Fermentation

  2026cites this paper
• Quality characteristics of bread produced by mixed fermentation with Kluyveromyces marxianus NIYC1 and lactic acid bacteria

  2025cites this paper
• Analyzing the effect of glucose availability on the ethyl acetate production by Kluyveromyces marxianus under iron limitation conditions by metabolic flux analysis approach

  2025cites this paper
• Tri-Functional CRISPR Screen Reveals Overexpression of QDR2 and QDR3 Transporters Increase Fumaric Acid Production in Kluyveromyces marxianus

  2025cites this paper
• Metabolic engineering and adaptive laboratory evolution of Kluyveromyces Marxianus for lactic acid production

  2025cites this paper
• Multi-omics data and model integration reveal the main mechanisms associated with respiro-fermentative metabolism and ethanol stress responses in Kluyveromyces marxianus

  2024cites this paper
• Unlocking the potential of Kluyveromyces marxianus in the definition of aroma composition of cheeses

  2024cites this paper
• Kluyveromyces as promising yeast cell factories for industrial bioproduction: From bio-functional design to applications.

  2023cites this paper
• Transfer of disulfide bond formation modules via yeast artificial chromosomes promotes the expression of heterologous proteins in Kluyveromyces marxianus

  2023influential citation
• Genetic Variability and Its Influence on the Fermentative Parameters of Kluyveromyces marxianus

  2023influential citation
• Pichia pastoris growth—coupled heme biosynthesis analysis using metabolic modelling

  2023cites this paper
• The Potential of Using Istrian Albumin Cheese Whey in the Production of Whey Distillate

  2023cites this paper
• Rice bran extract as an alternative nutritional supplement for Kluyveromyces marxianus

  2022cites this paper
• Kluyveromyces marxianus as a Platform in Synthetic Biology for the Production of Useful Materials

  2022cites this paper
• Kinetic and Stoichiometric Modeling-Based Analysis of Docosahexaenoic Acid (DHA) Production Potential by Crypthecodinium cohnii from Glycerol, Glucose and Ethanol

  2022cites this paper
• Optimization of fermentation for γ-aminobutyric acid (GABA) production by yeast Kluyveromyces marxianus C21 in okara (soybean residue)

  2022cites this paper
• Past, Present, and Future Perspectives on Whey as a Promising Feedstock for Bioethanol Production by Yeast

  2022cites this paper
• merlin, an improved framework for the reconstruction of high-quality genome-scale metabolic models

  2022cites this paper
• Kluyveromyces marxianus as a microbial cell factory for lignocellulosic biomass valorisation.

  2022cites this paper
• Metabolic Modeling of Hermetia illucens Larvae Resource Allocation for High-Value Fatty Acid Production

  2022cites this paper
• IMFLer: A Web Application for Interactive Metabolic Flux Analysis and Visualization

  2021cites this paper
• merlin v4.0: an updated platform for the reconstruction of high-quality genome-scale metabolic models

  2021cites this paper
• Integrative Gene Expression and Metabolic Analysis Tool IgemRNA

  2021cites this paper
• Optimization of Synthetic Media Composition for Kluyveromyces marxianus Fed-Batch Cultivation

  2021cites this paper
• Non-conventional yeasts as superior production platforms for sustainable fermentation based bio-manufacturing processes

  2020cites this paper
• Valorization of apple pomaces for biofuel production: A biorefinery approach

  2020cites this paper
• Microbial β-Galactosidases of industrial importance: Computational studies on the effects of point mutations on the lactose hydrolysis reaction.

  2020cites this paper
• Paint4Net: visualisation toolbox for COBRA

  2020cites this paper
• Dynamical Behavior of a 3‐Dimensional Continuous Bioreactor

  2020cites this paper
• The Model System Saccharomyces cerevisiae Versus Emerging Non-Model Yeasts for the Production of Biofuels

  2020cites this paper
• Prediction of fermentative parameters from mathematical modeling using thermotolerant probiotic yeast

  2020cites this paper
• Soybean residue (okara) fermentation with the yeast Kluyveromyces marxianus

  2019cites this paper
• Grape pomace fermentation and cell wall degradation by Kluyveromyces marxianus Y885

  2019cites this paper
• Synthesis of polyketides from low cost substrates by the thermotolerant yeast Kluyveromyces marxianus

  2019cites this paper
• Integration of comprehensive data and biotechnological tools for industrial applications of Kluyveromyces marxianus

  2019cites this paper
• Biotechnology and Bioengineering

  2019cites this paper
• Tomato Waste from Processing Industries as a Feedstock for Biofuel Production

  2019cites this paper
• Model-based metabolism design: constraints for kinetic and stoichiometric models

  2018cites this paper
• Dietary supplemental Kluyveromyces marxianus alters the serum metabolite profile in broiler chickens.

  2018cites this paper
• Uptake of iron by Kluyveromyces marxianus DSM 5422 cultivated in a whey‐based medium

  2018cites this paper
• Metabolic engineering of yeast for lignocellulosic biofuel production.

  2017cites this paper