Role of Toll-like receptors in systemic Candida albicans infections.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Frontiers in Bioscience

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2741/3263PMID 26709773
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Candida albicans phospholipomannan: a sweet spot for controlling host response/inflammation

  2015cited by this paper
• Antifungal innate immunity: recognition and inflammatory networks

  2014cited by this paper
• Expansion of Foxp3+ T-cell populations by Candida albicans enhances both Th17-cell responses and fungal dissemination after intravenous challenge

  2014cited by this paper
• New insights into innate immune control of systemic candidiasis

  2014cited by this paper
• Role of IFN-gamma in immune responses to Candida albicans infections.

  2014cited by this paper
• Gut microbiota promote hematopoiesis to control bacterial infection.

  2014cited by this paper
• Toll-Like Receptor Signaling Pathways

  2014cited by this paper
• Brothers in Arms: Th17 and Treg Responses in Candida albicans Immunity

  2014cited by this paper
• Microbiota-Derived Compounds Drive Steady-State Granulopoiesis via MyD88/TICAM Signaling

  2014cited by this paper
• Epidemiology and risk factors for invasive candidiasis

  2014cited by this paper
• Novel Structural Features in Candida albicans Hyphal Glucan Provide a Basis for Differential Innate Immune Recognition of Hyphae Versus Yeast*

  2013cited by this paper
• Mannosylation in Candida albicans: role in cell wall function and immune recognition

  2013cited by this paper
• Candida albicans secreted aspartic proteases 4–6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism

  2013cited by this paper
• Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

  2013cited by this paper
• The role of galectin‐3 in phagocytosis of Candida albicans and Candida parapsilosis by human neutrophils

  2013cited by this paper
• Galectin-3 plays an important role in protection against disseminated candidiasis.

  2013cited by this paper
• Pathogen Recognition Receptors: Ligands and Signaling Pathways by Toll-Like Receptors

  2013cited by this paper
• Candida and candidaemia. Susceptibility and epidemiology.

  2013cited by this paper
• Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

  2013cited by this paper
• CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.

  2013cited by this paper
• Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

  2013cited by this paper
• Candida albicans stimulates in vivo differentiation of haematopoietic stem and progenitor cells towards macrophages by a TLR2‐dependent signalling

  2013cited by this paper
• C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection.

  2013cited by this paper
• Interactions of Candida albicans with host epithelial surfaces

  2013cited by this paper
• TLRs control hematopoiesis during infection

  2013cited by this paper
• Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce

  2013cited by this paper
• Thriving within the host: Candida spp. interactions with phagocytic cells

  2013cited by this paper
• Recognition of fungal RNA by TLR7 has a nonredundant role in host defense against experimental candidiasis

  2012cited by this paper
• Immunochemistry of pathogenic yeast, Candida species, focusing on mannan

  2012cited by this paper
• Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-α production.

  2012cited by this paper
• Host defence against Candida albicans and the role of pattern-recognition receptors.

  2012cited by this paper
• Glycosylation of Candida albicans Cell Wall Proteins Is Critical for Induction of Innate Immune Responses and Apoptosis of Epithelial Cells

  2012cited by this paper
• The Effects of TLR Activation on T-Cell Development and Differentiation

  2012cited by this paper
• Fungal pathogens—a sweet and sour treat for toll-like receptors

  2012cited by this paper
• An Overview of Fungal Infections

  2012cited by this paper
• Th17 cells in immunity to Candida albicans.

  2012cited by this paper
• Difference in Fine Specificity to Polysaccharides of Candida albicans Mannoprotein between Mouse SIGNR1 and Human DC-SIGN

  2012cited by this paper
• Direct Toll‐Like Receptor‐Mediated Stimulation of Hematopoietic Stem and Progenitor Cells Occurs In Vivo and Promotes Differentiation Toward Macrophages

  2012cited by this paper
• Candida albicans Induces Selective Development of Macrophages and Monocyte Derived Dendritic Cells by a TLR2 Dependent Signalling

  2011cited by this paper
• Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages

  2011cited by this paper
• Toll-Like Receptor 9 Modulates Macrophage Antifungal Effector Function during Innate Recognition of Candida albicans and Saccharomyces cerevisiae

  2011cited by this paper
• The role of Dectin-1 in the host defence against fungal infections.

  2011cited by this paper
• Candida albicans Cell Wall Glycosylation May Be Indirectly Required for Activation of Epithelial Cell Proinflammatory Responses

  2011cited by this paper
• Conventional Dendritic Cells Mount a Type I IFN Response against Candida spp. Requiring Novel Phagosomal TLR7-Mediated IFN-β Signaling

  2011cited by this paper
• Recognition of yeast nucleic acids triggers a host‐protective type I interferon response

  2011cited by this paper
• C‐type lectin SIGNR1 enhances cellular oxidative burst response against C. albicans in cooperation with Dectin‐1

  2011cited by this paper
• Immunity to fungal infections

  2011cited by this paper
• Dectin-1 and Dectin-2 in innate immunity against fungi.

  2011cited by this paper
• Absence of TLR2 influences survival of neutrophils after infection with Candida albicans.

  2010cited by this paper
• Absence of functional TLR4 impairs response of macrophages after Candida albicans infection.

  2010cited by this paper
• Signalling through TLR2/MyD88 induces differentiation of murine bone marrow stem and progenitor cells to functional phagocytes in response to Candida albicans

  2010cited by this paper
• Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans.

  2010cited by this paper
• The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2.

  2010cited by this paper
• Variable recognition of Candida albicans strains by TLR4 and lectin recognition receptors.

  2010cited by this paper
• CARD9 Mediates Dectin-2-induced IκBα Kinase Ubiquitination Leading to Activation of NF-κB in Response to Stimulation by the Hyphal Form of Candida albicans*

  2010cited by this paper
• Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

  2009cited by this paper
• Cutting Edge: Candida albicans Hyphae Formation Triggers Activation of the Nlrp3 Inflammasome1

  2009cited by this paper
• Candida albicans triggers proliferation and differentiation of hematopoietic stem and progenitor cells by a MyD88-dependent signaling.

  2009cited by this paper
• Toll-Like Receptor 9-Dependent Activation of Myeloid Dendritic Cells by Deoxynucleic Acids from Candida albicans

  2009cited by this paper
• Candida albicans phospholipomannan triggers inflammatory responses of human keratinocytes through Toll‐like receptor 2

  2009cited by this paper
• An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans.

  2009cited by this paper
• Human dectin-1 deficiency and mucocutaneous fungal infections.

  2009cited by this paper
• Dectin‐1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

  2008cited by this paper
• Dendritic Cell Interaction with Candida albicans Critically Depends on N-Linked Mannan*

  2008cited by this paper
• Enhanced proinflammatory response to the Candida albicans gpi7 null mutant by murine cells.

  2008cited by this paper
• The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans1

  2008cited by this paper
• Redundant role of TLR9 for anti-Candida host defense.

  2008cited by this paper
• Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.

  2008cited by this paper
• Antifungal defense turns 17

  2007cited by this paper
• Both viable and killed Candida albicans cells induce in vitro production of TNF-alpha and IFN-gamma in murine cells through a TLR2-dependent signalling.

  2007cited by this paper
• Phenotypic and functional features of human Th17 cells

  2007cited by this paper
• Receptors and pathways in innate antifungal immunity: the implication for tolerance and immunity to fungi.

  2007cited by this paper
• Innate immunity--cross-talk with adaptive immunity through pattern recognition receptors and cytokines.

  2007cited by this paper
• Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

  2007cited by this paper
• Endoplasmic Reticulum α-Glycosidases of Candida albicans Are Required for N Glycosylation, Cell Wall Integrity, and Normal Host-Fungus Interaction

  2007cited by this paper
• Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors.

  2007influential reference
• Dectin-1 is required for beta-glucan recognition and control of fungal infection.

  2007cited by this paper
• IL‐23 and the Th17 pathway promote inflammation and impair antifungal immune resistance

  2007cited by this paper
• Cutting Edge: TLR2 Directly Triggers Th1 Effector Functions1

  2007cited by this paper
• Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

  2007cited by this paper
• Epidemiology of Invasive Candidiasis: a Persistent Public Health Problem

  2007cited by this paper
• Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans

  2007cited by this paper
• Innate control of adaptive immunity: dendritic cells and beyond.

  2007influential reference
• TLR-mediated innate immune recognition.

  2007cited by this paper
• CpG oligodeoxynucleotides protect mice from lethal challenge with Candida albicans via a pathway involving tumor necrosis factor-alpha-dependent interleukin-12 induction.

  2007cited by this paper
• Both viable and killed Candida albicans cells induce in vitro production of TNF-α and IFN-γ in murine cells through a TLR2-dependent signalling

  2007cited by this paper
• Expression and function of Toll-like receptors in T lymphocytes.

  2007cited by this paper
• A Drug-Sensitive Genetic Network Masks Fungi from the Immune System

  2006cited by this paper
• Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

  2006cited by this paper
• Molecular organization of the cell wall of Candida albicans and its relation to pathogenicity.

  2006cited by this paper
• Toll-like receptor 4 defective mice carrying point or null mutations do not show increased susceptibility to Candida albicans in a model of hematogenously disseminated infection.

  2006cited by this paper
• Toll-like receptors on regulatory T cells: expanding immune regulation.

  2006cited by this paper
• Pathogen recognition and innate immunity.

  2006cited by this paper
• TLR signaling

  2006cited by this paper
• TLR2, but not TLR4, triggers cytokine production by murine cells in response to Candida albicans yeasts and hyphae.

  2006cited by this paper
• Dectin-2 Is a Pattern Recognition Receptor for Fungi That Couples with the Fc Receptor γ Chain to Induce Innate Immune Responses*

  2006cited by this paper
• Toll‐like receptor stimulation as a third signal required for activation of human naive B cells

  2006cited by this paper
• Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA

  2006influential reference
• TLR signaling.

  2006influential reference
• Specific Recognition of Candida albicans by Macrophages Requires Galectin-3 to Discriminate Saccharomyces cerevisiae and Needs Association with TLR2 for Signaling1

  2006cited by this paper

• Candida albicans Impact on the Progression, Morphology, and Cellular Integrity of Biofilm Formation on the Surfaces of Implants; Current Knowledge and Future Perspectives

  2025cites this paper
• Type 1 diabetes mellitus (T1DM) does not affect whole blood responses to alginate-based microspheres despite plasma lipid and glucose differences

  2025cites this paper
• Platelet-Sourced TGF-β Promotes Th17 Responses and Enhances Airway Neutrophilia

  2025cites this paper
• Exploring the relationship between serum 25-hydroxyvitamin D levels and intestinal fungal communities and their metabolites in postmenopausal Chinese women

  2025cites this paper
• Candida Infections: The Role of Saliva in Oral Health—A Narrative Review

  2025cites this paper
• The Role of TLR2/TLR4 Receptors in Host Genetic Susceptibility to Recurrent Vulvovaginitis

  2025cites this paper
• Toll-like receptors (TLRs) in the trained immunity era

  2025cites this paper
• Unveiling the hidden players: exploring the role of gut mycobiome in cancer development and treatment dynamics

  2024cites this paper
• Metagenomic symphony of the intestinal ecosystem: How the composition affects the mind.

  2024cites this paper
• Long-Lasting Enhanced Cytokine Responses Following SARS-CoV-2 BNT162b2 mRNA Vaccination

  2024cites this paper
• AIM2 enhances Candida albicans infection through promoting macrophage apoptosis via AKT signaling

  2024cites this paper
• Fungal vaccines and adjuvants: a tool to reveal the interaction between host and fungi

  2024cites this paper
• IRF7 Exacerbates Candida albicans Infection by Compromising CD209-Mediated Phagocytosis and Autophagy-Mediated Killing in Macrophages.

  2024cites this paper
• Interleukin inhibitors and the associated risk of candidiasis

  2024cites this paper
• Stress in the microbiome-immune crosstalk

  2024cites this paper
• Gut microbiota signatures and fecal metabolites in postmenopausal women with osteoporosis

  2023cites this paper
• Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation to Elucidate the Molecular Targets and Potential Mechanism of Phoenix dactylifera (Ajwa Dates) against Candidiasis

  2023cites this paper
• MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions

  2023cites this paper
• The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly.

  2022cites this paper
• Itraconazole-Loaded Ufasomes: Evaluation, Characterization, and Anti-Fungal Activity against Candida albicans

  2022cites this paper
• Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis

  2022cites this paper
• Mannan-Binding Lectin Regulates the Th17/Treg Axis Through JAK/STAT and TGF-β/SMAD Signaling Against Candida albicans Infection

  2022cites this paper
• Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

  2021cites this paper
• COVID-19 Impairs Immune Response to Candida albicans

  2021cites this paper
• Pathogenicity Mechanism of Candida albicans

  2021cites this paper
• Candida Pathogenicity and Interplay with the Immune System.

  2021cites this paper
• Insights into the toll‐like receptors in sexually transmitted infections

  2020cites this paper
• Dectin-1 Stimulation of Hematopoietic Stem and Progenitor Cells Occurs In Vivo and Promotes Differentiation Toward Trained Macrophages via an Indirect Cell-Autonomous Mechanism

  2020cites this paper
• Candida albicans Shields the Periodontal Killer Porphyromonas gingivalis from Recognition by the Host Immune System and Supports the Bacterial Infection of Gingival Tissue

  2020cites this paper
• Effects of Cadmium on Neutrophil Biology and the Potential Role in Autoantigen Formation in Rheumatoid Arthritis

  2020cites this paper
• Leishmania species‐dependent functional duality of toll‐like receptor 2

  2019cites this paper
• TLR3 Is a Negative Regulator of Immune Responses Against Paracoccidioides brasiliensis

  2019cites this paper
• Dynamic quadripolar RadioFrequency and vulvodynia

  2018cites this paper
• Differences in interleukin-1β release-inducing activity of Candida albicans toward dendritic cells and macrophages.

  2018cites this paper
• Interleukin-2 and other cytokines in candidiasis: expression, clinical significance, and future therapeutic targets.

  2018cites this paper
• Systemic Candidiasis and TLR2 Agonist Exposure Impact the Antifungal Response of Hematopoietic Stem and Progenitor Cells

  2018cites this paper
• 3,6-Dihydroxyflavone: A Potent Inhibitor with Anti-Inflammatory Activity Targeting Toll-like Receptor 2

  2018cites this paper
• Role of pathogen‐associated molecular patterns (PAMPS) in immune responses to fungal infections

  2017cites this paper
• Endosomal sensing of fungi: current understanding and emerging concepts

  2017cites this paper
• Recognition of Candida albicans by gingival fibroblasts: The role of TLR2, TLR4/CD14, and MyD88

  2017cites this paper
• Role of microglia in fungal infections of the central nervous system

  2017cites this paper
• Role of TLR1, TLR2 and TLR6 in the modulation of intestinal inflammation and Candida albicans elimination

  2017cites this paper
• Candidiasis vaginal : estudio de receptores y mediadores inmunes innatos locales involucrados en la patogenia de la infección

  2017cites this paper
• Candida Infections and Human Defensins.

  2017cites this paper
• Toll‐like receptor 2: An important immunomodulatory molecule during Helicobacter pylori infection

  2017cites this paper
• Transcriptome analysis of hybrid tilapia (Oreochromis spp.) with Streptococcus agalactiae infection identifies Toll‐like receptor pathway‐mediated induction of NADPH oxidase complex and piscidins as primary immune‐related responses

  2017cites this paper
• TLR2 modulates gut colonization and dissemination of Candida albicans in a murine model.

  2016cites this paper
• Computational Discovery and Experimental Confirmation of TLR9 Receptor Antagonist Leads

  2016cites this paper
• Immune Response to Candida albicans Infection

  2016cites this paper
• Human Epithelial Cells Discriminate between Commensal and Pathogenic Interactions with Candida albicans

  2016cites this paper
• Gene expression profile of THP-1 cells treated with heat-killed Candida albicans.

  2016cites this paper
• Immunosuppression, peripheral inflammation and invasive infection from endogenous gut microbiota activate retinal microglia in mouse models

  2016cites this paper
• TLR2, TLR4 and Dectin-1 signalling in hematopoietic stem and progenitor cells determines the antifungal phenotype of the macrophages they produce.

  2016cites this paper
• Local and Systemic Inflammation in Localized, Provoked Vestibulodynia: A Systematic Review

  2016cites this paper
• Specific Human and Candida Cellular Interactions Lead to Controlled or Persistent Infection Outcomes during Granuloma-Like Formation

  2016cites this paper
• TLR-2 Signaling Promotes IL-17A Production in CD4+CD25+Foxp3+ Regulatory Cells during Oropharyngeal Candidiasis

  2015cites this paper
• Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells.

  2015cites this paper
• ORAL CANDIDIASIS : A REVIEW IN HIV SEROPOSITIVE PATIENTS

  2015cites this paper
• Age-related alteration of expression and function of TLRs and NK activity in oral candidiasis.

  2015cites this paper
• Retinal microglia are activated by systemic fungal infection.

  2014cites this paper
• The immunomodulatory effect of propolis on receptors expression, cytokine production and fungicidal activity of human monocytes

  2014cites this paper
• Role of IFN-gamma in immune responses to Candida albicans infections.

  2014cites this paper
• pseudomallei-Infected Mouse Macrophages Bacterial Elimination in Burkholderia To Interfere with Intracellular α Protein of Signal Regulatory Protein Inhibits the TRIF-Dependent - and Armadillo Motif-Containing α Sterile-

  2014cites this paper