Natural products: A lead for drug discovery and development

Natural products are used since ancient times in folklore for the treatment of various ailments. Plant‐derived products have been recognized for many years as a source of therapeutic agents and structural diversity. A literature survey has been carried out to determine the utility of natural molecules and their modified analogs or derivatives as pharmacological active entities. This review presents a study on the importance of natural products in terms of drug discovery and development. It describes how the natural components can be utilized after small modifications in new perspectives. Various new modifications in structure offer a unique opportunity to establish a new molecular entity with better pharmacological potential. It was concluded that in this current era, new attempts are taken to utilize the compounds derived from natural sources as novel drug candidates, with a focus to find and discover new effective molecules that were referred to as “new entities of natural product drug discovery.”

• Publication year

  2021

• Venue

  Phytotherapy Research

• Publication date

  2021-04-13

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/ptr.7099PMID 33847440
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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