Genetic characterization of the Saccharomyces cerevisiae translational initiation suppressors sui1, sui2 and SUI3 and their effects on HIS4 expression.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Genetics

• Publication date

  1990-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 2179049PMCID PMC1203942
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Yeast adenylate cyclase catalytic domain is carboxy terminal

  2004cited by this paper
• 23 – β-Galactosidase Gene Fusions for Analyzing Gene Expression in Escherichia coli and Yeast

  1989cited by this paper
• Mutations in the structural genes for eukaryotic initiation factors 2 alpha and 2 beta of Saccharomyces cerevisiae disrupt translational control of GCN4 mRNA.

  1989cited by this paper
• Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.

  1989cited by this paper
• Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.

  1988cited by this paper
• tRNAi(met) functions in directing the scanning ribosome to the start site of translation.

  1988cited by this paper
• Mutational analysis of the HIS4 translational initiator region in Saccharomyces cerevisiae

  1988cited by this paper
• Mutations at a Zn(II) finger motif in the yeast elF-2β gene alter ribosomal start-site selection during the scanning process

  1988cited by this paper
• Genetic selection for mutations that reduce or abolish ribosomal recognition of the HIS4 translational initiator region

  1988cited by this paper
• Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process.

  1988cited by this paper
• Mutations in elongation factor EF-1 alpha affect the frequency of frameshifting and amino acid misincorporation in Saccharomyces cerevisiae.

  1988cited by this paper
• The relationship between the "TATA" sequence and transcription initiation sites at the HIS4 gene of Saccharomyces cerevisiae.

  1985cited by this paper
• tRNA, suppression, and the code.

  1985cited by this paper
• Genetic map of Saccharomyces cerevisiae, edition 9.

  1985cited by this paper
• DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase.

  1985cited by this paper
• Codon recognition during frameshift suppression in Saccharomyces cerevisiae

  1984cited by this paper
• Beta-galactosidase gene fusions for analyzing gene expression in escherichia coli and yeast.

  1983cited by this paper
• A short nucleotide sequence required for regulation of HIS4 by the general control system of yeast.

  1983cited by this paper
• Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertase.

  1982cited by this paper
• The nucleotide sequence of the HIS4 region of yeast.

  1982cited by this paper
• Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase.

  1982cited by this paper
• Suppression in the Yeast Saccharomyces cerevisiae

  1982cited by this paper
• Yeast genes fused to beta-galactosidase in Escherichia coli can be expressed normally in yeast.

  1981cited by this paper
• Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

  1980cited by this paper
• Evaluation of the "scanning model" for initiation of protein synthesis in eucaryotes.

  1980cited by this paper
• How do eucaryotic ribosomes select initiation regions in messenger RNA?

  1978cited by this paper
• Integration of amino acid biosynthesis into the cell cycle of Saccharomyces cerevisiae.

  1975cited by this paper
• Genetic Mapping in Saccharomyces IV. Mapping of Temperature-Sensitive Genes and Use of Disomic Strains in Localizing Genes.

  1973cited by this paper
• Temperature-sensitive Mutants of Yeast Exhibiting a Rapid Inhibition of Protein Synthesis

  1968cited by this paper
• Biochemical Mutants in the Smut Fungus Ustilago Maydis.

  1949cited by this paper

• Translation Initiation Fidelity Defective Mutations in eIF5 and eIF2β Show Distinct Sensitivity to the Sequence Context for Recognition of the UUG Start Codon.

  2025cites this paper
• A little protein makes big news in translation initiation.

  2025cites this paper
• The crucial role of CFAS in maintaining acid-stress homeostasis of Hypsizygus marmoreus.

  2025cites this paper
• eIF1 and eIF5 dynamically control translation start site fidelity

  2025cites this paper
• eIF1 and eIF5 dynamically control translation start site fidelity

  2024cites this paper
• eIF2β zinc-binding domain interacts with the eIF2γ subunit through the guanine nucleotide binding interface to promote Met-tRNAiMet binding

  2024cites this paper
• Translational fidelity screens in mammalian cells reveal eIF3 and eIF4G2 as regulators of start codon selectivity

  2023cites this paper
• Non-AUG translation initiation in mammals

  2022cites this paper
• Altered proteome in translation initiation fidelity defective eIF5G31R mutant causes oxidative stress and DNA damage

  2022cites this paper
• Ribosomal mutation in helix 32 of 18S rRNA alters fidelity of eukaryotic translation start site selection

  2019cites this paper
• Start Codon Recognition in Eukaryotic and Archaeal Translation Initiation: A Common Structural Core

  2019cites this paper
• DDX3X and specific initiation factors modulate FMR1 repeat‐associated non‐AUG‐initiated translation

  2019cites this paper
• Fidelity of HIS4 start codon selection influences 3-amino-1,2,4-triazole sensitivity in GTPase activating protein function defective eIF5

  2018cites this paper
• MEHMO syndrome mutation EIF2S3-I259M impairs initiator Met-tRNAiMet binding to eukaryotic translation initiation factor eIF2

  2018cites this paper
• Defect in the GTPase activating protein (GAP) function of eIF5 causes repression of GCN4 translation.

  2017cites this paper
• EIF2S3 Mutations Associated with Severe X‐Linked Intellectual Disability Syndrome MEHMO

  2017cites this paper
• Non-AUG translation: a new start for protein synthesis in eukaryotes

  2017cites this paper
• Why is start codon selection so precise in eukaryotes?

  2014cites this paper
• Influence of translation factor activities on start site selection in six different mRNAs

  2013cites this paper
• ESTABLISHING THE FIDELITY OF START CODON RECOGNITION: ROLE OF EUKARYOTIC INITIATION FACTOR 2

  2013cites this paper
• Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery.

  2011cites this paper
• Crystal Structure of the Eukaryotic 40S Ribosomal Subunit in Complex with Initiation Factor 1

  2011cites this paper
• The Role of eIF1 in Translation Initiation Codon Selection in Caenorhabditis elegans

  2010cites this paper
• Initiation context modulates autoregulation of eukaryotic translation initiation factor 1 (eIF1)

  2010cites this paper
• The molecular basis of translational control.

  2009cites this paper
• eIF1 controls multiple steps in start codon recognition during eukaryotic translation initiation.

  2009cites this paper
• Multiple translation initiation factor Sui1 related sequences in mammalian genomes

  2009cites this paper
• Translation Initiation Factor 2γ Mutant Alters Start Codon Selection Independent of Met-tRNA Binding

  2008influential citation
• Yeast phenotypic assays on translational control.

  2007cites this paper
• Translation factor control of ribosome conformation during start codon selection.

  2007cites this paper
• Specific requirements for translational regulation by a nascent peptide that stalls ribosomes in response to arginine

  2006cites this paper
• Where to begin? The mechanism of translation initiation codon selection in eukaryotes.

  2006cites this paper
• Communication between eukaryotic translation initiation factors 5 and 1A within the ribosomal pre-initiation complex plays a role in start site selection.

  2006cites this paper
• Rôle du facteur d'initiation e/aIF2 dans le démarrage de la traduction chez les Eucaryotes et chez les archées.

  2005cites this paper
• The saccharomyces cerevisiae arginine attenuator peptide regulates translation and mRNA decay

  2005cites this paper
• The molecular mechanics of eukaryotic translation.

  2003cites this paper
• Yeast as a sensor of factors affecting the accuracy of protein synthesis

  2003cites this paper
• Molecular cloning of a full-length cDNA and gene from Coffea arabica encoding a protein homologous to the yeast translation initiation factor SUI1: expression analysis in plant organs

  2003cites this paper
• Translation initiation at non-AUG codons mediated by weakened association of eukaryotic initiation factor (eIF) 2 subunits.

  2002cites this paper
• Biochemical Analysis of the eIF2βγ Complex Reveals a Structural Function for eIF2α in Catalyzed Nucleotide Exchange*

  2001cites this paper
• Yeast frameshift suppressor mutations in the genes coding for transcription factor Mbf1p and ribosomal protein S3: evidence for autoregulation of S3 synthesis.

  2001cites this paper
• Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange.

  2001cites this paper
• Nonsense-mediated mRNA reduction and pre-mRNA processing in drosophila.

  2000cites this paper
• A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivo.

  2000cites this paper
• A European perspective on Neospora caninum.

  2000cites this paper
• Suppressors of translation initiation defect in hem12 locus of Saccharomyces cerevisiae.

  2000influential citation
• Conserved sequences in the beta subunit of archaeal and eukaryal translation initiation factor 2 (eIF2), absent from eIF5, mediate interaction with eIF2gamma.

  2000cites this paper
• Regulation of translation initiation following stress

  1999cites this paper
• Genetic interactions between a null allele of the RIT1 gene encoding an initiator tRNA-specific modification enzyme and genes encoding translation factors in Saccharomyces cerevisiae

  1999cites this paper
• An internal open reading frame triggers nonsense‐mediated decay of the yeast SPT10 mRNA

  1999cites this paper
• The β Subunit of Eukaryotic Translation Initiation Factor 2 Binds mRNA through the Lysine Repeats and a Region Comprising the C2-C2 Motif

  1999cites this paper
• Structure and interactions of the translation initiation factor eIF1

  1999cites this paper
• Cloning and Characterization of a Human Genotoxic and Endoplasmic Reticulum Stress-inducible cDNA That Encodes Translation Initiation Factor 1(eIF1A121/SUI1)*

  1999cites this paper
• The β Subunit of Eukaryotic Translation Initiation Factor 2 Binds mRNA through the Lysine Repeats and a Region Comprising the C2-C2 Motif

  1999cites this paper
• Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.

  1999cites this paper
• Pleiotropic deficiencies of the laccase-derepressed mutant lah-1 are caused by constitutively increased expression of the cross-pathway control gene cpc-1 in Neurospora crassa

  1998cites this paper
• The Mof2/Sui1 Protein Is a General Monitor of Translational Accuracy

  1998influential citation
• Studying Protein Synthesis Factors in Yeast: Structure, Function and Regulation

  1998cites this paper
• IDENTIFYING GENES ENCODING COMPONENTS OF THE PROTEIN SYNTHESIS MACHINERY OF THE YEAST SACCHAROMYCES CEREVISIAE

  1998cites this paper
• The b Subunit of Eukaryotic Translation Initiation Factor 2 Binds mRNA through the Lysine Repeats and a Region Comprising the C 2 -C 2 Motif

  1998cites this paper
• Translational Regulation of Yeast GCN4

  1997cites this paper
• GTP hydrolysis controls stringent selection of the AUG start codon during translation initiation in Saccharomyces cerevisiae.

  1997influential citation
• A dominant mutation in the Chlamydomonas reinhardtii nuclear gene SIM30 suppresses translational defects caused by initiation codon mutations in chloroplast genes.

  1997cites this paper
• SUI1/p16 is required for the activity of eukaryotic translation initiation factor 3 in Saccharomyces cerevisiae

  1996cites this paper
• General and Cross-Pathway Controls of Amino Acid Biosynthesis

  1996cites this paper
• Mutations in GCD11, the structural gene for eIF‐2 gamma in yeast, alter translational regulation of GCN4 and the selection of the start site for protein synthesis.

  1995cites this paper
• Casein kinase II mediates multiple phosphorylation of Saccharomyces cerevisiae eIF-2 alpha (encoded by SUI2), which is required for optimal eIF-2 function in S. cerevisiae

  1994cites this paper
• The gene encoding eIF-2 beta in S. cerevisiae maps to chromosome XVI.

  1994cites this paper
• Genetics of Translation Initiation Factors in Saccharomyces cerevisiae

  1993cites this paper
• SSL2, a suppressor of a stem-loop mutation in the HIS4 leader encodes the yeast homolog of human ERCC-3.

  1992cites this paper
• Genetic and physical maps of Saccharomyces cerevisiae, edition 11

  1992cites this paper
• Control of translation initiation in Saccharomyces cerevisiae.

  1992cites this paper
• Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

  1992cites this paper
• Selection-induced mutations occur in yeast.

  1992cites this paper
• SSL1, a suppressor of a HIS4 5'-UTR stem-loop mutation, is essential for translation initiation and affects UV resistance in yeast.

  1992cites this paper
• Isolation and characterization of SUA5, a novel gene required for normal growth in Saccharomyces cerevisiae.

  1992cites this paper
• cis- and trans-acting suppressors of a translation initiation defect at the cyc1 locus of Saccharomyces cerevisiae.

  1992cites this paper
• MicroReview Control of translation initiation in Saccharomyces cerevisiae

  1992cites this paper
• The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon

  1992influential citation
• Mutations activating the yeast eIF-2 alpha kinase GCN2: isolation of alleles altering the domain related to histidyl-tRNA synthetases

  1992cites this paper
• Mutation analysis of the Cys-X2-Cys-X19-Cys-X2-Cys motif in the beta subunit of eukaryotic translation initiation factor 2.

  1992cites this paper
• Extragenic suppressors of a translation initiation defect in the cyc1 gene of Saccharomyces cerevisiae.

  1991cites this paper
• Gene Products that Mediate Translation Initiation in Yeast

  1990cites this paper
• Translation in Yeast Mitochondria: A Review of General Features and a Case of mRNA-Specific Positive Control

  1990cites this paper
• Scanning, internal initiation and the control of the initiation of protein synthesis.

  1990cites this paper