Blood–brain barrier structure and function and the challenges for CNS drug delivery

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Inherited Metabolic Disease

• Publication date

  2013-04-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s10545-013-9608-0PMID 23609350
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• New strategies for the treatment of lysosomal storage diseases (review).

  2013cited by this paper
• Structure-activity relationship study of compounds binding to large amino acid transporter 1 (LAT1) based on pharmacophore modeling and in situ rat brain perfusion.

  2013cited by this paper
• The flexibility of P-glycoprotein for its poly-specific drug binding from molecular dynamics simulations

  2013cited by this paper
• Deficiency in Mural Vascular Cells Coincides with Blood–Brain Barrier Disruption in Alzheimer's Disease

  2013cited by this paper
• Establishment of a simplified in vitro porcine blood–brain barrier model with high transendothelial electrical resistance

  2013cited by this paper
• Immunologic Privilege in the Central Nervous System and the Blood–Brain Barrier

  2013cited by this paper
• Systemic Delivery of a Glucosylceramide Synthase Inhibitor Reduces CNS Substrates and Increases Lifespan in a Mouse Model of Type 2 Gaucher Disease

  2012cited by this paper
• The anatomical and cellular basis of immune surveillance in the central nervous system

  2012cited by this paper
• Human Blood-Brain Barrier Endothelial Cells Derived from Pluripotent Stem Cells

  2012cited by this paper
• Molecular Characterisation of Transport Mechanisms at the Developing Mouse Blood–CSF Interface: A Transcriptome Approach

  2012cited by this paper
• Theranostic liposomes loaded with quantum dots and apomorphine for brain targeting and bioimaging

  2012cited by this paper
• Gene therapy approaches for lysosomal storage disorders, a good model for the treatment of mendelian diseases

  2012cited by this paper
• Barrier Mechanisms in the Developing Brain

  2012cited by this paper
• CNS Penetration of Intrathecal-Lumbar Idursulfase in the Monkey, Dog and Mouse: Implications for Neurological Outcomes of Lysosomal Storage Disorder

  2012cited by this paper
• Anti-Aβ-MAb and dually decorated nanoliposomes: effect of Aβ1-42 peptides on interaction with hCMEC/D3 cells.

  2012cited by this paper
• Contribution of brain inflammation to neuronal cell death in neuronopathic forms of Gaucher's disease.

  2012cited by this paper
• Synthetic genistein derivatives as modulators of glycosaminoglycan storage

  2012cited by this paper
• Blood–spinal cord barrier pericyte reductions contribute to increased capillary permeability

  2012cited by this paper
• The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol.

  2012cited by this paper
• Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

  2012cited by this paper
• Human Immunodeficiency Virus-1 Uses the Mannose-6-Phosphate Receptor to Cross the Blood-Brain Barrier

  2012cited by this paper
• Is there a clinical future for polymeric nanoparticles as brain-targeting drug delivery agents?

  2012cited by this paper
• Pathophysiology of the Neurovascular Unit: Disease Cause or Consequence?

  2012cited by this paper
• Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease.

  2012cited by this paper
• Human ABC transporter ABCG2 in cancer chemotherapy: drug molecular design to circumvent multidrug resistance.

  2012cited by this paper
• Delivery of drugs to the brain via the blood brain barrier using colloidal carriers

  2012cited by this paper
• Capture, crawl, cross: the T cell code to breach the blood-brain barriers.

  2012cited by this paper
• In vitro blood-brain barrier models: current and perspective technologies.

  2012influential reference
• Overview and introduction: The blood–brain barrier in health and disease

  2012influential reference
• In vitro models of the blood-brain barrier.

  2012cited by this paper
• Relocalization of Junctional Adhesion Molecule A during Inflammatory Stimulation of Brain Endothelial Cells

  2012cited by this paper
• Intracisternal enzyme replacement therapy in lysosomal storage diseases: routes of absorption into brain

  2011cited by this paper
• Modelling the neurovascular unit and the blood-brain barrier with the unique function of pericytes.

  2011cited by this paper
• Engaging neuroscience to advance translational research in brain barrier biology

  2011cited by this paper
• Intracerebroventricular enzyme infusion corrects central nervous system pathology and dysfunction in a mouse model of metachromatic leukodystrophy.

  2011cited by this paper
• In vitro modeling of the blood-brain barrier: simplicity versus complexity.

  2011cited by this paper
• Identification of proline residues in or near the transmembrane helices of the human breast cancer resistance protein (BCRP/ABCG2) that are important for transport activity and substrate specificity.

  2011cited by this paper
• Blood-Brain Barrier Impairment in an Animal Model of MPS III B

  2011cited by this paper
• Clarifying lysosomal storage diseases.

  2011cited by this paper
• Spatial and temporal correlation between neuron loss and neuroinflammation in a mouse model of neuronopathic Gaucher disease.

  2011cited by this paper
• How well can in vitro brain microcapillary endothelial cell models predict rodent in vivo blood-brain barrier permeability?

  2011cited by this paper
• Central nervous system pericytes in health and disease

  2011cited by this paper
• The impact of pericytes on the blood-brain barrier integrity depends critically on the pericyte differentiation stage.

  2011cited by this paper
• Heterogeneity of CNS myeloid cells and their roles in neurodegeneration

  2011cited by this paper
• Slice Cultures as a Model to Study Neurovascular Coupling and Blood Brain Barrier In Vitro

  2011cited by this paper
• Therapies for neurological disease in the mucopolysaccharidoses.

  2011cited by this paper
• Intercellular Interactomics of Human Brain Endothelial Cells and Th17 Lymphocytes: A Novel Strategy for Identifying Therapeutic Targets of CNS Inflammation

  2011cited by this paper
• Evaluation of miglustat treatment in patients with type III mucopolysaccharidosis: a randomized, double-blind, placebo-controlled study.

  2011cited by this paper
• Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.

  2011cited by this paper
• Physicochemical Selectivity of the BBB Microenvironment Governing Passive Diffusion—Matching with a Porcine Brain Lipid Extract Artificial Membrane Permeability Model

  2011cited by this paper
• Intrathecal enzyme replacement therapy for mucopolysaccharidosis I: translating success in animal models to patients.

  2011cited by this paper
• Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line.

  2011cited by this paper
• Pericytes: developmental, physiological, and pathological perspectives, problems, and promises.

  2011cited by this paper
• Transport of Arylsulfatase A across the Blood-Brain Barrier in Vitro*

  2011cited by this paper
• Blood-brain barrier P450 enzymes and multidrug transporters in drug resistance: a synergistic role in neurological diseases.

  2011cited by this paper
• Predicting P-Glycoprotein-Mediated Drug Transport Based On Support Vector Machine and Three-Dimensional Crystal Structure of P-glycoprotein

  2011cited by this paper
• Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood-brain barrier.

  2011cited by this paper
• Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: the positive effect of long-term aspirin treatment.

  2011cited by this paper
• In vitro models of the blood-brain barrier.

  2011cited by this paper
• Circumventricular organs

  2011cited by this paper
• The role of inflammation in epilepsy

  2011cited by this paper
• Correction of neurological disease of mucopolysaccharidosis IIIB in adult mice by rAAV9 trans-blood-brain barrier gene delivery.

  2011cited by this paper
• Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein

  2010cited by this paper
• Lessons learnt from animal models: pathophysiology of neuropathic lysosomal storage disorders

  2010cited by this paper
• Pathophysiology of neuropathic lysosomal storage disorders

  2010cited by this paper
• ABC transporters and cytochromes P450 in the human central nervous system: influence on brain pharmacokinetics and contribution to neurodegenerative disorders

  2010cited by this paper
• Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging.

  2010cited by this paper
• Genistein Improves Neuropathology and Corrects Behaviour in a Mouse Model of Neurodegenerative Metabolic Disease

  2010cited by this paper
• Structure and function of the blood-brain barrier.

  2010cited by this paper
• Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.

  2010cited by this paper
• Pericytes regulate the blood–brain barrier

  2010cited by this paper
• Therapeutic approaches for neuronopathic lysosomal storage disorders

  2010cited by this paper
• Pericytes are required for blood–brain barrier integrity during embryogenesis

  2010cited by this paper
• Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier.

  2010cited by this paper
• Common and Uncommon Pathogenic Cascades in Lysosomal Storage Diseases*

  2010cited by this paper
• The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls.

  2010cited by this paper
• Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

  2010cited by this paper
• New Strategies for Enzyme Replacement Therapy for Lysosomal Storage Diseases

  2010cited by this paper
• Neurodegeneration and the neurovascular unit

  2010cited by this paper
• Trans-generational exposure to low levels of rhodamine B does not adversely affect litter size or liver function in murine mucopolysaccharidosis type IIIA.

  2010cited by this paper
• Diphtheria Toxin Mutant CRM197-Mediated Transcytosis across Blood–Brain Barrier In Vitro

  2010cited by this paper
• Structure and function of the human breast cancer resistance protein (BCRP/ABCG2).

  2010cited by this paper
• Pericyte-Mediated Regulation of Capillary Diameter: A Component of Neurovascular Coupling in Health and Disease

  2010cited by this paper
• Transport of interleukin‐1 across cerebromicrovascular endothelial cells

  2009cited by this paper
• P-glycoprotein deficient mouse in situ blood-brain barrier permeability and its prediction using an in combo PAMPA model.

  2009cited by this paper
• A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes.

  2009cited by this paper
• Will the original glucose transporter isoform please stand up!

  2009cited by this paper
• Enzyme replacement improves ataxic gait and central nervous system histopathology in a mouse model of metachromatic leukodystrophy.

  2009cited by this paper
• Addressing Central Nervous System (CNS) Penetration in Drug Discovery: Basics and Implications of the Evolving New Concept

  2009cited by this paper
• Wnt/β-catenin signaling is required for CNS, but not non-CNS, angiogenesis

  2009cited by this paper
• Physiological pathway for low-density lipoproteins across the blood-brain barrier: transcytosis through brain capillary endothelial cells in vitro.

  2008cited by this paper
• Endothelial transcytosis in health and disease

  2008cited by this paper
• Generation of a set of simple, interpretable ADMET rules of thumb.

  2008cited by this paper
• ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood–brain barrier

  2008cited by this paper
• A combined artificial chromosome-stem cell therapy method in a model experiment aimed at the treatment of Krabbe’s disease in the Twitcher mouse

  2008cited by this paper
• Assays to predict drug permeation across the blood-brain barrier, and distribution to brain.

  2008cited by this paper
• Substrate reduction therapy

  2008cited by this paper
• Human ABC transporters ABCG2 (BCRP) and ABCG4

  2008cited by this paper
• Lysosomal storage diseases and the blood-brain barrier.

  2008cited by this paper
• Chemically modified β-glucuronidase crosses blood–brain barrier and clears neuronal storage in murine mucopolysaccharidosis VII

  2008cited by this paper

• Recent advances in biofunctional ultrasound contrast agents with polymeric shells

  2026cites this paper
• Search for marker proteins to assess blood–brain barrier development

  2026cites this paper
• Bridging the blood-brain barrier: strategies to improve delivery of biologics to tumors in the brain

  2026cites this paper
• Consequences of irradiation on blood-brain tumor barrier model of Diffuse Midline Glioma: characterization of physical and metabolic properties.

  2026cites this paper
• Apolipoprotein E4 in Alzheimer’s Disease: Role in Pathology, Lipid Metabolism, and Drug Treatment

  2026cites this paper
• Cell swelling and upright mounting-based imaging for high-resolution visualization of intracellular trafficking across the BBB using conventional confocal microscopy

  2026cites this paper
• Utilizing nanotechnology to diagnose and treat central nervous system disorders

  2026cites this paper
• Synthetic urinary biomarker probes for disease detection and monitoring

  2026cites this paper
• Pathogenicity of Elizabethkingia miricola causing mass mortalities of American bullfrog (Aquarana catesbeiana) and its induced host immune response.

  2026cites this paper
• Airborne particulates and brain health: The role of PM2.5 in blood-brain-barrier dysfunction.

  2026cites this paper
• Histone and non-histone (de)acetylation impact on the blood-brain barrier

  2026cites this paper
• Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

  2026cites this paper
• Neuroinflammation and Neurological Sequelae of COVID-19: Insights from Clinical and Experimental Evidence

  2026cites this paper
• Plant-Derived Exosome-Like Nanovesicles for CNS Drug Delivery and Gut–Brain Axis Modulation: A Narrative Review

  2025cites this paper
• Nanomedicine for targeting brain Neurodegeneration: Critical barriers and circadian rhythm Considerations.

  2025cites this paper
• Functionalized Nanoparticles: A Promising Approach for Effective Management of Alzheimer’s Disease

  2025cites this paper
• ApoE4 disrupts intracellular trafficking and iron homeostasis in a reproducible iPSC-based model of human brain endothelial cells

  2025cites this paper
• Natural polysaccharides in colloidal drug delivery systems for brain glioma therapy: Mechanisms and advancements.

  2025cites this paper
• Targeting glucose transporters in parkinson’s disease: a novel metabolic approach for disease modification

  2025cites this paper
• Tetrabutylphosphonium‐Based Amino Acid Ionic Liquids: Synthesis, Properties, Catalytic Activity, in Silico Analysis, and Study of Biological Activity

  2025cites this paper
• Lab Protocols for Coxsackievirus B3 Infection Using Brain-Like Endothelial Cells Derived from Induced-Pluripotent Human Stem Cells.

  2025cites this paper
• The curse of blood–brain barrier and blood–tumor barrier in malignant brain tumor treatment

  2025cites this paper
• Discovery of blood-brain barrier transport-related surface proteins by DIA-Orbitrap high-resolution mass spectrometry.

  2025cites this paper
• Neisseria meningitidis regulates P-glycoprotein transporter activity in brain endothelial cells via sphingosine 1–phosphate receptor 1

  2025cites this paper
• The impact of therapeutic radiation on drug distribution across the blood-brain barrier in normal mouse brain and orthotopic glioblastoma tumors

  2025cites this paper
• Biomarker-Guided Dynamic Liquid Biopsy System for Enhanced Detection of Glioblastoma Recurrence via Blood–Brain Barrier Permeability Optimisation

  2025cites this paper
• CAR T cell therapy for central nervous system solid tumors: current progress and future directions

  2025cites this paper
• Evaluation of the distribution of the boron neutron capture therapy drug 4-borono-L-phenylalanine (BPA) in a rat brain tumor model using liquid chromatography/tandem mass spectrometry (LC-MS/MS).

  2025cites this paper
• Advances in PET Imaging of α7 Nicotinic Receptors: From Radioligand Development to CNS Applications

  2025cites this paper
• A Systematic Quantitative Approach to Rational Drug Design and the Discovery of Novel Human Antigen R (HuR) Inhibitors.

  2025cites this paper
• PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier

  2025cites this paper
• The Secretome of Brain Endothelial Cells Exposed to the Pyrrolizidine Alkaloid Monocrotaline Induces Astrocyte Reactivity and Is Neurotoxic

  2025cites this paper
• What Works, What Doesn't, and Why? An Industrial Perspective on Absorption Modeling.

  2025cites this paper
• Nanoparticle Interactions with the Blood Brain Barrier: Insights from Drosophila and Implications for Human Astrocyte Targeted Therapies

  2025cites this paper
• Nanocarrier Strategies in Glioblastoma: Overcoming Barriers to Effective Brain Tumor Therapy

  2025cites this paper
• Permeability Benchmarking: Guidelines for Comparing in Silico, in Vitro, and in Vivo Measurements

  2025cites this paper
• Systematic Review of Pre-Clinical Systems Using Artificial Microenvironments and Anti-Migratory Drugs to Control Migration of Glioblastoma Cells

  2025cites this paper
• Feature-Guided Machine Learning for Studying Passive Blood–Brain Barrier Permeability to Aid Drug Discovery

  2025cites this paper
• The glutamate-GABA balance axis in immune and stress regulation of aquaculture invertebrates

  2025cites this paper
• Development and characterisation of a thermoreversible sol-gel for intranasal delivery of MRI and PET imaging agents.

  2025cites this paper
• Cancer brain metastasis: molecular mechanisms and therapeutic strategies

  2025cites this paper
• Advancements and challenges in CAR T cell therapy for pediatric brain tumors: A review

  2025cites this paper
• Unlocking the Human Blood-brain barrier (BBB) Characteristics for the Development of Nano-Delivery Strategies for Central Nervous System Therapies

  2025cites this paper
• Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies

  2025cites this paper
• Recent status and trends regarding oxidative stress in gliomas (2013 - 2025): a systematic review and bibliometric analysis

  2025cites this paper
• Development of novel electrospun nanofibers loaded with Levosulpiride and Cannabidiol encapsulated in cyclodextrin-phospholipid inclusion complex for ameliorated treatment of anxiety and depression.

  2025cites this paper
• A humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the blood–brain barrier

  2025cites this paper
• Marine Derived Strategies Against Neurodegeneration

  2025cites this paper
• The therapeutic efficacy of nanoparticles in the treatment of alzheimer's disease.

  2025cites this paper
• Pathogenesis-based treatment strategies for brain metastases from non-small cell cancer.

  2025cites this paper
• Advancing through the blood-brain barrier: mechanisms, challenges and drug delivery strategies

  2025cites this paper
• Fungal metabolite Ochratoxin A inhibits MrkD1P of multidrug-resistant Klebsiella pneumoniae: Integrated computational and in vitro validation

  2025cites this paper
• Checkpoint antibody receptor modified ARMed CAR T circumvents the suppressive immunome in GBM

  2025cites this paper
• Smart Nanometals: An Approach to Transform Brain Cancer Diagnosis and Therapy

  2025cites this paper
• Advances in Modeling the Inner Blood–Retinal Barrier: From Static Tissue Cell Cultures to Microphysiological Systems

  2025cites this paper
• Rebamipide (Mucosta®), a clinically approved drug, alleviates neuroinflammation and dopaminergic neurodegeneration in a Parkinson’s disease model

  2025cites this paper
• Data-driven feedback augments ultrasound nanotheranostics in brain tumors

  2025cites this paper
• Smart Bioelectronics for Real-Time Diagnosis and Therapy of Body Organ Functions.

  2025cites this paper
• Navigation Between Alzheimer’s Disease (AD) and Its Various Pathophysiological Trajectories: The Pathogenic Link to Neuroimmunology—Genetics and Neuroinflammation

  2025cites this paper
• Review: The potential role of placental extracellular vesicles in blood-brain barrier disruption and neuroinflammation in preeclampsia.

  2025cites this paper
• Advancements in Nanoemulsion-Based Drug Delivery Across Different Administration Routes

  2025cites this paper
• Alanine and glutathione targeting of dopamine- or ibuprofen-coupled polypeptide nanocarriers increases both crossing and protective effects on a blood–brain barrier model

  2025cites this paper
• Construction of ROS-responsive cascade-targeted liposomes and investigation of their anti-AD effects.

  2025cites this paper
• Towards a New Dawn for Neuro-Oncology: Nanomedicine at the Service of Drug Delivery for Primary and Secondary Brain Tumours

  2025cites this paper
• Delivery of monoclonal antibodies to the brain: the impact of nanocarrier structure

  2025cites this paper
• Sensing 5-HT by specific aptamer modified nanostructures in chronic restraint stress-induced depression mice.

  2025cites this paper
• Unraveling the therapeutic potential of Tephrosia linearis: Anti-inflammatory, analgesic activity, and molecular docking approaches

  2025cites this paper
• Blood–Brain Barrier Penetration of Novel 4-Trifluoromethyl-Coumarin Hybrids with Antibacterial Properties as Potential Brain Therapeutics in the Context of Spatially Diverse Healthcare Systems

  2025cites this paper
• 3D in vitro blood–brain barrier models: recent advances and their role in brain disease research and therapy

  2025cites this paper
• Strategies for Transcytosis-Based Delivery across the Blood-Brain Barrier.

  2025cites this paper
• Discovery of Brain-Penetrative Negative Allosteric Modulators of NMDA Receptors Using FEP-Guided Structure Optimization and Membrane Permeability Prediction

  2025cites this paper
• Use of Quantum Dots as Nanotheranostic Agents: Emerging Applications in Rare Genetic Diseases.

  2025cites this paper
• Engineering biomimetic tissue barrier models on chips: From design and fabrication to applications in disease modeling and drug screening.

  2025cites this paper
• In vitro assessment of P-glycoprotein-mediated antiseizure medications efflux in a blood-brain barrier cell model.

  2025cites this paper
• Modulation of the blood–brain barrier permeability by patient-derived glioblastoma stem cell secretome

  2025cites this paper
• Design and Development of Sulfonamide-Chalcones as Antiepileptic Candidates: Computational and Zebrafish-Based Validation Approaches

  2025cites this paper
• Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

  2025cites this paper
• Tumor exosomal miR-221-3p induces glycolysis through the LIFR/GLUT1 pathway to destroy the cerebral vascular endothelial cell barrier and promote breast cancer brain metastasis

  2025cites this paper
• Microfluidic biosensors and devices for brain tumor diagnosis and monitoring.

  2025cites this paper
• Ultrasound frequency-controlled microbubble dynamics in brain vessels regulate the enrichment of inflammatory pathways in the blood-brain barrier

  2024cites this paper
• Utilizing Multifaceted Approaches to Target Drug Delivery in the Brain: From Nanoparticles to Biological Therapies

  2024influential citation
• Insight into central nervous system targeted nanostructured lipid carriers via the nose to brain pathway

  2024cites this paper
• Advancements in strategies for overcoming the blood–brain barrier to deliver brain-targeted drugs

  2024influential citation
• Unveiling the hidden connection: the blood-brain barrier’s role in epilepsy

  2024cites this paper
• Advanced tissue technologies of blood-brain barrier organoids as high throughput toxicity readouts in drug development

  2024cites this paper
• Role of blood–brain barrier dysfunction in the development of poststroke epilepsy

  2024cites this paper
• Metal-Based Nanoclusters for Diagnosis and Treatment of Brain Diseases

  2024cites this paper
• Nose to brain strategy coupled to nano vesicular system for natural products delivery: Focus on synaptic plasticity in Alzheimer's disease

  2024cites this paper
• Blood–brain barrier alterations and their impact on Parkinson’s disease pathogenesis and therapy

  2024influential citation
• Multiple chemical sensitivity: a review of its pathophysiology

  2024cites this paper
• Case Report of Complete Response to Olaparib in a Patient with Breast Cancer Brain Metastases

  2024cites this paper
• Nanoparticles in CNS Therapeutics: Pioneering Drug Delivery Advancements.

  2024cites this paper
• Macrophages and HLA-Class II Alleles in Multiple Sclerosis: Insights in Therapeutic Dynamics

  2024cites this paper
• A new frontier in neuropharmacology: Recent progress in natural products research for blood–brain barrier crossing

  2024cites this paper
• Non-genomic ERα-AMPK signaling regulates sex-dependent Bcrp transport activity at the blood-brain barrier.

  2024cites this paper
• Regulation of blood-brain barrier integrity by Dmp1-expressing astrocytes through mitochondrial transfer

  2024cites this paper
• Challenges and opportunities in neurometabolic disease treatment with enzyme delivery

  2024cites this paper
• Upregulation of Transferrin Receptor 1 (TfR1) but Not Glucose Transporter 1 (GLUT1) or CD98hc at the Blood–Brain Barrier in Response to Valproic Acid

  2024cites this paper
• Minimally invasive nasal infusion (MINI) approach for CNS delivery of protein therapeutics: A case study with ovalbumin.

  2024cites this paper
• Crosstalk Between the Nervous System and Colorectal Cancer

  2024cites this paper