Diet, the gut microbiome, and epigenetics.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Cancer Journal

• Publication date

  2014-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1097/PPO.0000000000000053PMID 24855003PMCID PMC4267719
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Gut microbes, diet, and cancer.

  2014cited by this paper
• Bacterial SET domain proteins and their role in eukaryotic chromatin modification

  2014cited by this paper
• Role of the Lower and Upper Intestine in the Production and Absorption of Gut Microbiota-Derived PUFA Metabolites

  2014cited by this paper
• Tea, Coffee, and Milk Consumption and Colorectal Cancer Risk

  2014cited by this paper
• Contribution of the 7β-hydroxysteroid dehydrogenase from Ruminococcus gnavus N53 to ursodeoxycholic acid formation in the human colon[S]

  2013cited by this paper
• Cytoplasmic 5′-3′ exonuclease Xrn1p is also a genome-wide transcription factor in yeast

  2013cited by this paper
• Implication of fermentable carbohydrates targeting the gut microbiota on conjugated linoleic acid production in high-fat-fed mice

  2013cited by this paper
• Time course production of urolithins from ellagic acid by human gut microbiota.

  2013cited by this paper
• Distinct Distal Gut Microbiome Diversity and Composition in Healthy Children from Bangladesh and the United States

  2013cited by this paper
• The Relationship Between Advances in Understanding the Microbiome and the Maturing Hygiene Hypothesis

  2013cited by this paper
• Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist.

  2013cited by this paper
• Impact of polyphenols from black tea and red wine/grape juice on a gut model microbiome

  2013cited by this paper
• Stool Microbiome and Metabolome Differences between Colorectal Cancer Patients and Healthy Adults

  2013cited by this paper
• 454 pyrosequencing reveals a shift in fecal microbiota of healthy adult men consuming polydextrose or soluble corn fiber.

  2012cited by this paper
• Human gut microbiome viewed across age and geography

  2012cited by this paper
• Chemoprevention of colorectal cancer with ursodeoxycholic acid: pro.

  2012cited by this paper
• Omega-3 fatty acids and cancers: a systematic update review of epidemiological studies

  2012cited by this paper
• Gut microbial metabolism of polyphenols from black tea and red wine/grape juice is source-specific and colon-region dependent.

  2012cited by this paper
• Structure, Function and Diversity of the Healthy Human Microbiome

  2012cited by this paper
• Impact of diet in shaping gut microbiota

  2012cited by this paper
• Epigenetic modulation of mechanisms involved in inflammation: Influence of selected polyphenolic substances on histone acetylation state

  2012cited by this paper
• The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation.

  2012cited by this paper
• Trends in mortality from cancers of the breast, colon, prostate, esophagus, and stomach in East Asia: role of nutrition transition

  2012cited by this paper
• The hallmarks of cancer

  2012cited by this paper
• The inhibition of the mammalian DNA methyltransferase 3a (Dnmt3a) by dietary black tea and coffee polyphenols

  2011cited by this paper
• Pharmacokinetic and chemoprevention studies on tea in humans.

  2011cited by this paper
• Function and disruption of DNA Methyltransferase 3a cooperative DNA binding and nucleoprotein filament formation

  2011cited by this paper
• Enterotypes of the human gut microbiome

  2011cited by this paper
• High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health.

  2011cited by this paper
• Variation of glucoraphanin metabolism in vivo and ex vivo by human gut bacteria.

  2011cited by this paper
• A whole-grain cereal-rich diet increases plasma betaine, and tends to decrease total and LDL-cholesterol compared with a refined-grain diet in healthy subjects

  2011cited by this paper
• Eating for two: how metabolism establishes interspecies interactions in the gut.

  2011cited by this paper
• Cancer epigenetics: above and beyond

  2011cited by this paper
• Hallmarks of cancer: the next generation.

  2011cited by this paper
• Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies

  2011cited by this paper
• Intake of n‐3 and n‐6 polyunsaturated fatty acids and development of colorectal cancer by subsite: Japan Public Health Center–based prospective study

  2011cited by this paper
• Propionate as a health-promoting microbial metabolite in the human gut.

  2011cited by this paper
• 13C tracer recovery in human stools after digestion of a fat-rich meal labelled with [1,1,1-13C3]tripalmitin and [1,1,1-13C3]triolein.

  2011cited by this paper
• Cancer chemoprevention by targeting the epigenome.

  2011cited by this paper
• Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

  2010cited by this paper
• Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.

  2010cited by this paper
• Molecular targets of epigenetic regulation and effectors of environmental influences.

  2010cited by this paper
• The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota.

  2010cited by this paper
• Cancer Statistics, 2010

  2010cited by this paper
• Ursodeoxycholic acid and chemoprevention of colorectal cancer.

  2010cited by this paper
• Metabolism of (-)-epigallocatechin gallate by rat intestinal flora.

  2010cited by this paper
• Sulforaphane Causes Epigenetic Repression of hTERT Expression in Human Breast Cancer Cell Lines

  2010cited by this paper
• Gastrointestinal microflora, food components and colon cancer prevention.

  2009cited by this paper
• Many roads to maturity: microRNA biogenesis pathways and their regulation

  2009cited by this paper
• n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon.

  2009cited by this paper
• Dietary Intake of ω-6 and ω-3 Fatty Acids and Risk of Colorectal Cancer in a Prospective Cohort of U.S. Men and Women

  2009cited by this paper
• Marine n‐3 and saturated fatty acids in relation to risk of colorectal cancer in Singapore Chinese: A prospective study

  2009cited by this paper
• Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

  2009cited by this paper
• Ellagitannin (BJA3121), an anti‐proliferative natural polyphenol compound, can regulate the expression of MiRNAs in HepG2 cancer cells

  2009cited by this paper
• Histone-deacetylase inhibition and butyrate formation: Fecal slurry incubations with apple pectin and apple juice extracts.

  2008cited by this paper
• A 22-year Prospective Study of Fish, n-3 Fatty Acid Intake, and Colorectal Cancer Risk in Men

  2008cited by this paper
• Chromatin-remodelling mechanisms in cancer.

  2008cited by this paper
• Dietary components impact histone modifications and cancer risk.

  2008cited by this paper
• Genome-wide methylation analysis of human colon cancer reveals similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

  2008cited by this paper
• Organization of butyrate synthetic genes in human colonic bacteria: phylogenetic conservation and horizontal gene transfer.

  2007cited by this paper
• Whole-grain wheat breakfast cereal has a prebiotic effect on the human gut microbiota: a double-blind, placebo-controlled, crossover study

  2007cited by this paper
• Pinto bean consumption changes SCFA profiles in fecal fermentations, bacterial populations of the lower bowel, and lipid profiles in blood of humans.

  2007cited by this paper
• Lipid Accumulation and Dendritic Cell Function in Cancer (49.10)

  2007cited by this paper
• Blood Levels of Long-Chain Polyunsaturated Fatty Acids, Aspirin, and the Risk of Colorectal Cancer

  2007cited by this paper
• Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors.

  2007cited by this paper
• Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria

  2007cited by this paper
• Understanding the effects of diet on bacterial metabolism in the large intestine

  2007cited by this paper
• Green tea and black tea consumption in relation to colorectal cancer risk: the Singapore Chinese Health Study.

  2007cited by this paper
• Histone deacetylases: target enzymes for cancer therapy

  2007cited by this paper
• Prospective Cohort Study of Green Tea Consumption and Colorectal Cancer Risk in Women

  2007cited by this paper
• Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice

  2006cited by this paper
• Lupin kernel fibre foods improve bowel function and beneficially modify some putative faecal risk factors for colon cancer in men

  2006cited by this paper
• Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence

  2006cited by this paper
• Reduced Dietary Intake of Carbohydrates by Obese Subjects Results in Decreased Concentrations of Butyrate and Butyrate-Producing Bacteria in Feces

  2006cited by this paper
• Association between consumption of cruciferous vegetables and condiments and excretion in urine of isothiocyanate mercapturic acids.

  2006cited by this paper
• Lupin kernel fiber consumption modifies fecal microbiota in healthy men as determined by rRNA gene fluorescent in situ hybridization

  2006cited by this paper
• Metabonomics approach to determine metabolic differences between green tea and black tea consumption.

  2006cited by this paper
• Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

  2006cited by this paper
• Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.

  2006cited by this paper
• Mixtures of SCFA, composed according to physiologically available concentrations in the gut lumen, modulate histone acetylation in human HT29 colon cancer cells

  2006cited by this paper
• Phase III trial of ursodeoxycholic acid to prevent colorectal adenoma recurrence.

  2005cited by this paper
• Green Tea and the Risk of Colorectal Cancer: Pooled Analysis of Two Prospective Studies in Japan

  2005cited by this paper
• Contribution of acetate to butyrate formation by human faecal bacteria.

  2004cited by this paper
• A Novel Mechanism of Chemoprotection by Sulforaphane

  2004cited by this paper
• A critical review of the bioavailability of glucosinolates and related compounds.

  2004cited by this paper
• Hydrolysis of Glucosinolates to Isothiocyanates after Ingestion of Raw or Microwaved Cabbage by Human Volunteers

  2004cited by this paper
• Microbial degradation products influence colon cancer risk: the butyrate controversy.

  2004cited by this paper
• Short chain fatty acid regulation of signaling genes expressed by the intestinal epithelium.

  2004cited by this paper
• Epigenetic gene silencing in cancer initiation and progression.

  2003cited by this paper
• Proceedings of the Third International Scientific Symposium on Tea and Human Health: Role of Flavonoids in the Diet The Epidemiology of Tea Consumption and Colorectal Cancer Incidence

  2003cited by this paper
• Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats

  2003cited by this paper
• The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation.

  2002cited by this paper
• Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria

  2002cited by this paper
• DNA methylation patterns and epigenetic memory.

  2002cited by this paper
• Synthesis of (-)-[4-3H]epigallocatechin gallate and its metabolic fate in rats after intravenous administration.

  2001cited by this paper
• The prebiotic effects of biscuits containing partially hydrolysed guar gum and fructo-oligosaccharides – a human volunteer study

  2001cited by this paper
• Metabolic fate of (-)-[4-(3)H]epigallocatechin gallate in rats after oral administration.

  2001cited by this paper
• The heterocyclic ring fission and dehydroxylation of catechins and related compounds by Eubacterium sp. strain SDG-2, a human intestinal bacterium.

  2001cited by this paper
• Formation of allyl isothiocyanate from sinigrin in the digestive tract of rats monoassociated with a human colonic strain of Bacteroides thetaiotaomicron.

  2001cited by this paper
• Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention.

  2000cited by this paper

• Bidirectional effect of intestinal microbiome and host in circadian rhythm disruption: Environmental factors and breast cancer development.

  2026cites this paper
• Impacts of prenatal nutrition on metabolic pathways in beef cattle: an integrative approach using metabolomics and metagenomics

  2025cites this paper
• Butyrate ameliorates lung inflammation in chronic obstructive pulmonary disease in association with the regulation of histone lactylation: A mechanistic study.

  2025cites this paper
• Inhibitory effects and amino acid metabolism regulations of active polyphenol from foxtail millet bran on chronic colitis in mice

  2025cites this paper
• Addiction Susceptibility: Genetic Factors, Personality Traits, and Epigenetic Interactions with the Gut Microbiome

  2025cites this paper
• Dietary variations drive divergent phenotypic, transcriptomic, and metatranscriptomic profiles in Biomphalaria glabrata, a schistosomiasis vector snail

  2025cites this paper
• Evaluation of the gut microbiome and sex hormones in postmenopausal women with newly diagnosed hormone receptor-positive breast cancer versus healthy women: a prospective case-control study

  2025cites this paper
• How Can Molecules Induce Hemorrhoids? The Role of Genetics and Epigenetics in Hemorrhoidal Disease

  2025cites this paper
• Obesity and cancer: unravelling the microbiome’s hidden role

  2025cites this paper
• Gut microbiome, a potential modulator of neuroepigenome.

  2025cites this paper
• Microbial metabolites as engines of behavioral variation across animals

  2025cites this paper
• Restricted vs. ad libitum feeding during sow gestation affects piglet performance, behavior, and fecal microbiota composition

  2025cites this paper
• The microbiota in breast cancer: dysbiosis, microbial metabolites, and therapeutic implications.

  2025cites this paper
• Impact of dietary carbohydrate, fat, or protein restriction on the human gut microbiome: a systematic review.

  2024cites this paper
• Gut microbiota, nutrition, and mental health

  2024cites this paper
• Insights into the Relationship Between the Gut Microbiome and Immune Checkpoint Inhibitors in Solid Tumors

  2024cites this paper
• The role of pharmacomicrobiomics in HIV prevention, treatment, and women’s health

  2024cites this paper
• Dysbiosis-epigenetics-immune system interaction and ageing health problems.

  2024cites this paper
• Dietary Bioactive Compounds Trigger Distinct Epigenetic and Metabolic Reprogramming in Lactobacillus acidophilus

  2024cites this paper
• Diet, Gut Microbes, and Cancer.

  2024cites this paper
• Microbial Metabolites-Induced Epigenetic Modifications for Inhibition of Colorectal Cancer: Current Status and Future Perspectives.

  2024cites this paper
• The potential influence of microplastics on the microbiome and disease susceptibility in sea turtles.

  2024cites this paper
• Biomarkers of food intake and their relevance to metabolic syndrome.

  2024cites this paper
• Navigating the Intersection: Sarcopenia and Sarcopenic Obesity in Inflammatory Bowel Disease

  2024cites this paper
• Amino Acids during Pregnancy and Offspring Cardiovascular–Kidney–Metabolic Health

  2024cites this paper
• Polyphenolic Compounds: Orchestrating Intestinal Microbiota Harmony during Aging

  2024cites this paper
• Construction of model animals to explore intestinal microbiome for detection of breast cancer

  2023cites this paper
• A New Paradigm in the Relationship between Gut Microbiota and Breast Cancer: β-glucuronidase Enzyme Identified as Potential Therapeutic Target

  2023cites this paper
• Exploring the human microbiome – A step forward for precision medicine in breast cancer

  2023cites this paper
• Global Impacts of Western Diet and Its Effects on Metabolism and Health: A Narrative Review

  2023cites this paper
• Interplay between Phytochemicals and the Colonic Microbiota

  2023cites this paper
• Composition of the maternal gastrointestinal microbiome as a predictor of neonatal birth weight

  2023cites this paper
• Epigenetic Modifications Induced by the Gut Microbiota May Result from What We Eat: Should We Talk about Precision Diet in Health and Disease?

  2023cites this paper
• Big Data in Gastroenterology Research

  2023cites this paper
• Epigenetics and the role of nutraceuticals in health and disease

  2023cites this paper
• Elucidating the gut microbiome alterations of tribal community of Arunachal Pradesh: perspectives on their lifestyle or food habits

  2022cites this paper
• Immunophysiology of the avian immune system

  2022cites this paper
• Holistic Integration of Omics Tools for Precision Nutrition in Health and Disease

  2022cites this paper
• Modulating Microbiota as a New Strategy for Breast Cancer Prevention and Treatment

  2022cites this paper
• Influences of the Immune System and Microbiome on the Etiology of ASD and GI Symptomology of Autistic Individuals.

  2022cites this paper
• Genesis and Mechanism of Some Cancer Types and an Overview on the Role of Diet and Nutrition in Cancer Prevention

  2022cites this paper
• Bugs as Drugs: Understanding the Linkage between Gut Microbiota and Cancer Treatment Microbiome in Cancer Therapy.

  2022cites this paper
• Gut microbial response to host metabolic phenotypes

  2022cites this paper
• A review on the application of bioinformatics tools in food microbiome studies

  2022cites this paper
• Altered gut metabolites and microbiota interactions are implicated in colorectal carcinogenesis and can be non-invasive diagnostic biomarkers

  2022cites this paper
• Impact of the gut microbiota on the immune system

  2022cites this paper
• Gut Microbiota Metabolites in Major Depressive Disorder—Deep Insights into Their Pathophysiological Role and Potential Translational Applications

  2022cites this paper
• Current understanding of gut microbiota in tackling COVID-19

  2021cites this paper
• The Sulfur Microbial Diet and Risk of Colorectal Cancer by Molecular Subtypes and Intratumoral Microbial Species in Adult Men

  2021cites this paper
• Short-Chain Fatty Acids as Therapeutic Agents in Colon Malignancies

  2021cites this paper
• [Dietary Patterns and Their Association with Diabetes Mellitus in Middle-Aged and Older Rural Population in Xinxiang County, Henan Province].

  2021cites this paper
• A Crosstalk between Diet, Microbiome and microRNA in Epigenetic Regulation of Colorectal Cancer

  2021cites this paper
• Nutrition and Cancer

  2021cites this paper
• Microbial dysbiosis and epigenetics modulation in cancer development - A chemopreventive approach.

  2021cites this paper
• Amino Acid-Induced Impairment of Insulin Signaling and Involvement of G-Protein Coupling Receptor

  2021cites this paper
• The Role of Epigenomic Regulatory Pathways in the Gut-Brain Axis and Visceral Hyperalgesia

  2021cites this paper
• Microbe-Based Therapies for Colorectal Cancer: Advantages and Limitations.

  2021cites this paper
• The link among microbiota, epigenetics, and disease development

  2021cites this paper
• The Interplay between Diet, Gut Microbes, and Host Epigenetics in Health and Disease.

  2021cites this paper
• A review on epigenetic effects of environmental factors causing and inhibiting cancer.

  2021cites this paper
• Evidence for Modulation of Substance Use Disorders by the Gut Microbiome: Hidden in Plain Sight

  2021cites this paper
• Priming for Life: Early Life Nutrition and the Microbiota-Gut-Brain Axis

  2021cites this paper
• Microbiome Research and Multi-Omics Integration for Personalized Medicine in Asthma

  2021cites this paper
• Exploring the Inflammatory Pathogenesis of Colorectal Cancer

  2021cites this paper
• Epigenetic aspects of the microbiota and psychiatric disorders

  2021cites this paper
• Adaptations and alterations of maternal microbiota: From physiology to pathology

  2021cites this paper
• [The Gut Microbiome and Its Clinical Implications in Anorexia Nervosa].

  2021cites this paper
• Effects of moderate exercise on hepatic amino acid and fatty acid composition, liver transcriptome, and intestinal microbiota in channel catfish (Ictalurus punctatus).

  2021cites this paper
• Potential Biomarkers, Risk Factors, and Their Associations with IgE-Mediated Food Allergy in Early Life: A Narrative Review

  2021cites this paper
• Microbial Diversity and Classification

  2021cites this paper
• Polysaccharides on the gut microbiome and epigenome

  2021cites this paper
• Interactions between the intestinal microbiota and epigenome in individuals with autism spectrum disorder

  2021cites this paper
• Epigenetics: A New Frontier in Probiotic Research.

  2020cites this paper
• Metabolite profile comparisons between ascending and descending colon tissue in healthy adults

  2020cites this paper
• Gastrointestinal Interaction between Dietary Amino Acids and Gut Microbiota: with Special Emphasis on Host Nutrition.

  2020cites this paper
• Gut Microbiota as Important Mediator Between Diet and DNA Methylation and Histone Modifications in the Host

  2020cites this paper
• Effects of Three Distinct 2-Week Long Diet Strategies After Transport on Weaned Pigs' Short and Long-Term Welfare Markers, Behaviors, and Microbiota

  2020cites this paper
• The inter-talk between Mycobacterium tuberculosis and the epigenetic mechanisms.

  2020cites this paper
• Microbial Alterations and Risk Factors of Breast Cancer: Connections and Mechanistic Insights

  2020cites this paper
• Epigenetic mechanisms of anti-cancer effects of dietary stilbenoids

  2020cites this paper
• Organosulfur Compounds: A Review of Their Anti-inflammatory Effects in Human Health

  2020cites this paper
• Effects of dietary rumen–protected Lys levels on rumen fermentation and bacterial community composition in Holstein heifers

  2020cites this paper
• Gut Microbiome Critically Impacts PCB-induced Changes in Metabolic Fingerprints and the Hepatic Transcriptome in Mice.

  2020cites this paper
• Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome – An Update

  2020cites this paper
• Epigenetic Mechanisms in Irritable Bowel Syndrome

  2020cites this paper
• Epigenetic Effects of Gut Metabolites: Exploring the Path of Dietary Prevention of Type 1 Diabetes

  2020cites this paper
• Workshop report: Toward the development of a human whole stool reference material for metabolomic and metagenomic gut microbiome measurements

  2020cites this paper
• Bioinformatics and machine learning in gastrointestinal microbiome research and clinical application.

  2020cites this paper
• Understanding the role of gut microbiota in the pathogenesis of schizophrenia.

  2020cites this paper
• Inflammation and Its Role in Obesity-Related Complications

  2020cites this paper
• The Role of the Gut Microbiome in Predicting Response to Diet and the Development of Precision Nutrition Models. Part II: Results.

  2019cites this paper
• Gut microbiota and physical frailty through the mediation of sarcopenia.

  2019cites this paper
• Prebiotic effect of fructo-oligosaccharides on the inner ear of DBA/2 J mice with early-onset progressive hearing loss.

  2019cites this paper
• Maternal epigenetic inheritance

  2019cites this paper
• Carbohydrate Nutrition and the Risk of Cancer

  2019cites this paper
• CpG and Non-CpG Methylation in the Diet–Epigenetics–Neurodegeneration Connection

  2019cites this paper
• The interaction between gut microbiome and nutrients on development of human disease through epigenetic mechanisms

  2019cites this paper
• Subsistence and Society in Prehistory

  2019cites this paper
• Sulforaphane - role in aging and neurodegeneration

  2019cites this paper
• Comparing DNA methylation profiles in saliva and intestinal mucosa

  2019cites this paper