RNA-binding proteins as regulators of gene expression.

Haruhiko Siomi,G. Dreyfuss

Published 1997 in Current Opinion in Genetics and Development

ABSTRACT

A plethora of post-transcriptional mechanisms are involved in essential steps in the pathway of genetic information expression in eukaryotes. These processes are specified by cis-acting signals on RNAs and are mediated by specific trans-acting factors, including RNA-binding proteins and small complementary RNAs. Recent information has begun to define the molecular mechanisms by which RNA-binding proteins recognize specific RNA sequences and influence the processing and function of RNA molecules.

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