Live, Attenuated Coronavirus Vaccines through the Directed Deletion of Group-Specific Genes Provide Protection against Feline Infectious Peritonitis

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Virology

• Publication date

  2004-04-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/jvi.78.8.3863-3871.2004PMID 15047802PMCID PMC374255
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Switching Species Tropism: an Effective Way To Manipulate the Feline Coronavirus Genome

  2003influential reference
• Lung pathology of fatal severe acute respiratory syndrome

  2003cited by this paper
• Engineering the Transmissible Gastroenteritis Virus Genome as an Expression Vector Inducing Lactogenic Immunity

  2003cited by this paper
• Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study

  2003cited by this paper
• Transmissible gastroenteritis coronavirus gene 7 is not essential but influences in vivo virus replication and virulence

  2003cited by this paper
• The Group-Specific Murine Coronavirus Genes Are Not Essential, but Their Deletion, by Reverse Genetics, Is Attenuating in the Natural Host

  2002cited by this paper
• Antibody-mediated enhancement of disease in feline infectious peritonitis: Comparisons with dengue hemorrhagic fever

  2002cited by this paper
• Heterologous Gene Expression from Transmissible Gastroenteritis Virus Replicon Particles

  2002cited by this paper
• Adverse effects of feline IL-12 during DNA vaccination against feline infectious peritonitis virus.

  2002cited by this paper
• Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS.

  2001influential reference
• Retargeting of Coronavirus by Substitution of the Spike Glycoprotein Ectodomain: Crossing the Host Cell Species Barrier

  2000cited by this paper
• Feline Infectious Peritonitis Viruses Arise by Mutation from Endemic Feline Enteric Coronaviruses

  1998cited by this paper
• Feline Coronavirus Type II Strains 79-1683 and 79-1146 Originate from a Double Recombination between Feline Coronavirus Type I and Canine Coronavirus

  1998cited by this paper
• Antibody-dependent enhancement of feline infectious peritonitis virus infection in feline alveolar macrophages and human monocyte cell line U937 by serum of cats experimentally or naturally infected with feline coronavirus.

  1998cited by this paper
• Persistence and Evolution of Feline Coronavirus in a Closed Cat-Breeding Colony

  1997cited by this paper
• Placebo-controlled evaluation of a modified life virus vaccine against feline infectious peritonitis: safety and efficacy under field conditions

  1997cited by this paper
• Comparison of the Amino Acid Sequence and Phylogenetic Analysis of the Peplomer, Integral Membrane and Nucleocapsid Proteins of Feline, Canine and Porcine Coronaviruses

  1996cited by this paper
• The Coronavirus Surface Glycoprotein

  1995cited by this paper
• The Coronaviridae: An Introduction

  1995cited by this paper
• Feline infectious peritonitis

  1995cited by this paper
• The Molecular Genetics of Feline Coronaviruses: Comparative Sequence Analysis of the ORF7a/7b Transcription Unit of Different Biotypes

  1995cited by this paper
• Infection enhancement of influenza A NWS virus in primary murine macrophages by anti‐hemagglutinin monoclonal antibody

  1992cited by this paper
• Monoclonal antibodies to the spike protein of feline infectious peritonitis virus mediate antibody-dependent enhancement of infection of feline macrophages

  1992cited by this paper
• Monoclonal antibody analysis of neutralization and antibody-dependent enhancement of feline infectious peritonitis virus

  1992cited by this paper
• A study of naturally occurring feline coronavirus infections in kittens

  1992cited by this paper
• Primary structure of the membrane and nucleocapsid protein genes of feline infectious peritonitis virus and immunogenicity of recombinant vaccinia viruses in kittens

  1991cited by this paper
• Early death after feline infectious peritonitis virus challenge due to recombinant vaccinia virus immunization

  1990cited by this paper
• Protection against feline infectious peritonitis by intranasal inoculation of a temperature-sensitive FIPV vaccine

  1990cited by this paper
• Assembly of coronavirus spike protein into trimers and its role in epitope expression

  1990cited by this paper
• Antibody-enhanced infection by HIV-1 via Fc receptor-mediated entry.

  1988cited by this paper
• Attempted immunisation of cats against feline infectious peritonitis using canine coronavirus

  1988cited by this paper
• Virologic and immunologic aspects of feline infectious peritonitis virus infection.

  1987cited by this paper
• Antibody-dependent enhancement of viral infectivity.

  1986cited by this paper
• Experimental inoculation of cats with human coronavirus 229E and subsequent challenge with feline infectious peritonitis virus.

  1985cited by this paper
• Experimental inoculation of cats with canine coronavirus and subsequent challenge with feline infectious peritonitis virus.

  1984cited by this paper
• Pathogenicity studies of feline coronavirus isolates 79-1146 and 79-1683.

  1984cited by this paper
• Coronaviridae1

  1983cited by this paper
• Attempted immunization of cats against feline infectious peritonitis, using avirulent live virus or sublethal amounts of virulent virus.

  1983cited by this paper
• Isolation of feline coronaviruses from two cats with diverse disease manifestations

  1981cited by this paper
• Cross-protection studies between feline infectious peritonitis and porcine transmissible gastroenteritis viruses

  1979cited by this paper
• Antibody-mediated enhancement of Flavivirus replication in macrophage-like cell lines

  1979cited by this paper
• Serologic studies of naturally occurring feline infectious peritonitis.

  1976cited by this paper
• Feline infectious peritonitis.

  1976cited by this paper

• Development and Validation of a Triplex RT-qPCR Assay for Rapid Clinical Diagnosis and Serotyping of Feline Infectious Peritonitis Virus

  2026cites this paper
• Safety and efficacy of live attenuated PEDV vaccines for neonatal protection

  2025cites this paper
• Attenuation and altered replication of IBV strain tl/CH/LDT3/03 after serial passage in chicken embryo fibroblasts and Vero cells

  2025cites this paper
• A colloidal gold immunochromatographic test strip based on mAbs anti-N protein to detect feline coronavirus

  2025cites this paper
• Mutations in feline infectious peritonitis virus nonstructural protein 14/16 methyltransferase attenuate the pathogenicity of the virus in cats

  2025cites this paper
• Effects of SADS‐CoV accessory proteins NS3a, NS7a, and NS7b on viral pathogenicity: A multi‐omics investigation

  2025cites this paper
• Development of a yeast-based CRISPR genome editing system for feline coronavirus

  2025cites this paper
• Potential Transcriptional Enhancers in Coronaviruses: From Infectious Bronchitis Virus to SARS-CoV-2

  2024cites this paper
• The SARS coronavirus accessory protein ORF3a rescues potassium conductance in yeast

  2024cites this paper
• Feline infectious peritonitis virus ORF7a is a virulence factor involved in inflammatory pathology in cats.

  2024cites this paper
• An adenovirus-vectored vaccine based on the N protein of feline coronavirus elicit robust protective immune responses.

  2024cites this paper
• Towards a Safer Future: Enhancing Vaccine Development to Combat Animal Coronaviruses

  2024cites this paper
• Development and characterization of reverse genetics systems of feline infectious peritonitis virus for antiviral research

  2024cites this paper
• An updated review of feline coronavirus: mind the two biotypes

  2023cites this paper
• Immunoinformatics-aided rational design of a multi-epitope vaccine targeting feline infectious peritonitis virus

  2023cites this paper
• Reverse Genetic Assessment of the Roles Played by the Spike Protein and ORF3 in Porcine Epidemic Diarrhea Virus Pathogenicity

  2023cites this paper
• SARS-CoV-2 ORF8 accessory protein is a virulence factor

  2023cites this paper
• SARS-CoV-2 accessory protein 7b forms homotetramers in detergent

  2022cites this paper
• Host-Genome Similarity Characterizes the Adaption of SARS-CoV-2 to Humans

  2022cites this paper
• An Exploration of Nanoparticle-Based Diagnostic Approaches for Coronaviruses: SARS-CoV-2, SARS-CoV and MERS-CoV

  2022cites this paper
• Naturally Occurring Bioactives as Antivirals: Emphasis on Coronavirus Infection

  2021cites this paper
• Comparative sequence analysis of the accessory and nucleocapsid genes of feline coronavirus strains isolated from cats diagnosed with effusive feline infectious peritonitis

  2021cites this paper
• Clinical and molecular aspects of veterinary coronaviruses

  2021cites this paper
• Systematizing the genomic order and relatedness in the open reading frames (ORFs) of the coronaviruses

  2021cites this paper
• Vaccines Targeting Numerous Coronavirus Antigens, Ensuring Broader Global Population Coverage: Multi-epitope and Multi-patch Vaccines.

  2021cites this paper
• Sleeping beauties and temporal evolution of the coronavirus literature

  2021influential citation
• Feline Coronavirus and Alpha-Herpesvirus Infections: Innate Immune Response and Immune Escape Mechanisms

  2021cites this paper
• The Current Status and Challenges in the Development of Vaccines and Drugs against Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2)

  2021cites this paper
• Interspecies Jumping of Bat Coronaviruses

  2021cites this paper
• Functions of Coronavirus Accessory Proteins: Overview of the State of the Art

  2021cites this paper
• Temporal evolution, most influential studies and sleeping beauties of the coronavirus literature

  2021cites this paper
• Establishment of Full-Length cDNA Clones and an Efficient Oral Infection Model for Feline Coronavirus in Cats

  2021cites this paper
• The molecular virology of coronaviruses

  2020cites this paper
• Successive Passage In Vitro Led to Lower Virulence and Higher Titer of A Variant Porcine Epidemic Diarrhea Virus

  2020cites this paper
• ADE and hyperinflammation in SARS-CoV2 infection- comparison with dengue hemorrhagic fever and feline infectious peritonitis

  2020cites this paper
• Infectious Subgenomic Amplicons method to expedite reverse genetics of SARS-CoV-2 and other coronaviruses

  2020cites this paper
• FCoV Viral Sequences of Systemically Infected Healthy Cats Lack Gene Mutations Previously Linked to the Development of FIP

  2020cites this paper
• Multiple novel non-canonically transcribed sub-genomic mRNAs produced by avian coronavirus infectious bronchitis virus

  2020cites this paper
• Vaccines based on virus-like nano-particles for use against Middle East Respiratory Syndrome (MERS) coronavirus

  2020cites this paper
• Understanding the Molecular Mechanism(s) of SARS-CoV2 Infection and Propagation in Human to Discover Potential Preventive and Therapeutic Approach

  2020cites this paper
• A Possible Path towards Rapid Development of Live-Attenuated SARS-CoV-2 Vaccines: Plunging into the Natural Pool

  2020cites this paper
• Novel Coronavirus (COVID-19) outbreak: A review on most targetable proteins (S and N) of SARS-CoV-2

  2020cites this paper
• Genetic manipulation of porcine deltacoronavirus reveals insights into NS6 and NS7 functions: a novel strategy for vaccine design

  2019cites this paper
• Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

  2019cites this paper
• Attenuation of a virulent swine acute diarrhea syndrome coronavirus strain via cell culture passage

  2019cites this paper
• Identification of peptide domains involved in the subcellular localization of the feline coronavirus 3b protein

  2019cites this paper
• S gene and 5a accessory gene are responsible for the attenuation of virulent infectious bronchitis coronavirus

  2019cites this paper
• Serological Screening for Coronavirus Infections in Cats

  2019cites this paper
• Modulation of the immune response by Middle East respiratory syndrome coronavirus

  2018cites this paper
• Recombinant live attenuated avian coronavirus vaccines with deletions in the accessory genes 3ab and/or 5ab protect against infectious bronchitis in chickens

  2018cites this paper
• Modulation of the immune response byMiddle East respiratory syndrome coronavirus

  2018cites this paper
• Feline coronavirus: Insights into viral pathogenesis based on the spike protein structure and function

  2018cites this paper
• Reverse Genetics for Type I Feline Coronavirus Field Isolate To Study the Molecular Pathogenesis of Feline Infectious Peritonitis

  2018cites this paper
• Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo

  2018cites this paper
• Identification and characterization of a Golgi retention signal in feline coronavirus accessory protein 7b

  2017cites this paper
• The Generation of Antibodies against HumanCoronavirus NL63 (HCoV-NL63) NucleocapsidProtein

  2017cites this paper
• Discovery of a novel accessory protein NS7a encoded by porcine deltacoronavirus

  2017cites this paper
• Severe acute respiratory syndrome coronavirus protein 7 a interacts with hSGT

  2017cites this paper
• A reverse genetics system for avian coronavirus infectious bronchitis virus based on targeted RNA recombination

  2017cites this paper
• Detection of feline coronavirus spike gene mutations as a tool to diagnose feline infectious peritonitis

  2017cites this paper
• Synthetic virus-like particles prepared via protein corona formation enable effective vaccination in an avian model of coronavirus infection

  2016cites this paper
• Coronavirus cis-Acting RNA Elements

  2016cites this paper
• Identification and subcellular localization of porcine deltacoronavirus accessory protein NS6

  2016cites this paper
• Feline Coronaviruses

  2016influential citation
• Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

  2016cites this paper
• Investigaciones recientes en peritonitis infecciosa felina

  2016cites this paper
• Prostaglandin regulation of immune responses against coronavirus infections

  2016cites this paper
• Characterization of monoclonal antibodies against feline coronavirus accessory protein 7b

  2015cites this paper
• Characterisation of different forms of the accessory gp3 canine coronavirus type I protein identified in cats

  2015cites this paper
• Development and evaluation of bivalent dna vaccine against avian infectious bronchitis

  2015cites this paper
• Genotyping coronaviruses associated with feline infectious peritonitis

  2015cites this paper
• Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak control

  2015cites this paper
• The ns12.9 Accessory Protein of Human Coronavirus OC43 Is a Viroporin Involved in Virion Morphogenesis and Pathogenesis

  2015cites this paper
• The ns 12 . 9 accessory protein of human coronavirus OC 43 is a 1 viroporin involved in virion morphogenesis and pathogenesis 2

  2015cites this paper
• Mutations of 3c and spike protein genes correlate with the occurrence of feline infectious peritonitis

  2014cites this paper
• Tackling feline infectious peritonitis via reverse genetics

  2014cites this paper
• Comparative In Vivo Analysis of Recombinant Type II Feline Coronaviruses with Truncated and Completed ORF3 Region

  2014influential citation
• Coronavirus virulence genes with main focus on SARS-CoV envelope gene

  2014cites this paper
• Effect of small interfering RNAs on in vitro replication and gene expression of feline coronavirus.

  2014cites this paper
• An update on feline infectious peritonitis: Virology and immunopathogenesis

  2014cites this paper
• Accessory proteins of SARS-CoV and other coronaviruses

  2014cites this paper
• Feline Infectious Peritonitis

  2014cites this paper
• Feline infectious peritonitis

  2014cites this paper
• RNA structure analysis of alphacoronavirus terminal genome regions

  2014cites this paper
• Viral Diseases of Ferrets

  2014cites this paper
• ORF7-encoded accessory protein 7a of feline infectious peritonitis virus as a counteragent against IFN-α-induced antiviral response.

  2014influential citation
• Novel antiviral strategies for feline coronavirus and feline calicivirus

  2014cites this paper
• Feline infectious peritonitis virus accessory proteins and type I interferon are fighting for dominance

  2014influential citation
• Identification and genotyping of feline infectious peritonitis-associated single nucleotide polymorphisms in the feline interferon-γ gene

  2014cites this paper
• Polymorphisms in the feline TNFA and CD209 genes are associated with the outcome of feline coronavirus infection

  2014cites this paper
• The role of cell-mediated immunity during coronavirus infections in cats: opportunities for therapeutic avenues?

  2013cites this paper
• The Human Coronavirus Nucleocapsid Protein and Its Effects on the Innate Immune Response

  2013cites this paper
• Systematic annotation and analysis of "virmugens"-virulence factors whose mutants can be used as live attenuated vaccines.

  2013cites this paper
• Recombinant feline coronaviruses as vaccine candidates confer protection in SPF but not in conventional cats

  2013influential citation
• The role of accessory proteins in the replication of feline infectious peritonitis virus in peripheral blood monocytes

  2012influential citation
• Molecular characterization of feline infectious peritonitis virus strain

  2012cites this paper
• Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines

  2012cites this paper
• Molecular Characterization of Feline Infectious Peritonitis Virus Strain DF-2 and Studies of the Role of ORF3abc in Viral Cell Tropism

  2012cites this paper
• Tropism Studies of the Role of ORF 3 abc in Viral Cell Infectious Peritonitis Virus Strain DF-2 and Molecular Characterization of Feline

  2012cites this paper
• Coronavirus Reverse Genetics

  2012influential citation