Proteomic analysis of the venom from the scorpion Tityus stigmurus: biochemical and physiological comparison with other Tityus species.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP

• Publication date

  2007-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.CBPC.2006.12.004PMID 17270501
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Wide phylogenetic distribution of Scorpine and long-chain beta-KTx-like peptides in scorpion venoms: identification of "orphan" components.

  2007cited by this paper
• Wide phylogenetic distribution of Scorpine and long-chain β-KTx-like peptides in scorpion venoms: Identification of “orphan” components

  2007cited by this paper
• K+ channel blockers: novel tools to inhibit T cell activation leading to specific immunosuppression.

  2006cited by this paper
• Moving pieces in a taxonomic puzzle: venom 2D-LC/MS and data clustering analyses to infer phylogenetic relationships in some scorpions from the Buthidae family (Scorpiones).

  2006cited by this paper
• Diversity of long-chain toxins in Tityus zulianus and Tityus discrepans venoms (Scorpiones, Buthidae): molecular, immunological, and mass spectral analyses.

  2006cited by this paper
• Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus.

  2006cited by this paper
• Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.

  2005cited by this paper
• Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily

  2005cited by this paper
• The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function.

  2005cited by this paper
• Scorpion Venom Peptides without Disulfide Bridges

  2005cited by this paper
• Molecular basis of a-KTx specificity

  2004cited by this paper
• Molecular basis of alpha-KTx specificity.

  2004cited by this paper
• Current views on scorpion toxins specific for K+-channels.

  2004cited by this paper
• Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

  2004cited by this paper
• Diversity of folds in animal toxins acting on ion channels.

  2004cited by this paper
• Individual variability in Tityus serrulatus (Scorpiones, Buthidae) venom elicited by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  2003cited by this paper
• Disulfide bridges and blockage of Shaker B K(+)-channels by another butantoxin peptide purified from the Argentinean scorpion Tityus trivittatus.

  2003cited by this paper
• Novel structural class of four disulfide-bridged peptides from Tityus serrulatus venom.

  2003cited by this paper
• Solution structure of a K+‐channel blocker from the scorpion Tityus cambridgei

  2002cited by this paper
• Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels.

  2002cited by this paper
• OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus.

  2001cited by this paper
• A hyaluronidase from Tityus serrulatus scorpion venom: isolation, characterization and inhibition by flavonoids.

  2001cited by this paper
• [Poisonous sting by Tityus stigmurus (Scorpiones; Buthidae) in the state of Bahia, Brazil].

  2000cited by this paper
• Peptides and genes coding for scorpion toxins that affect ion-channels.

  2000cited by this paper
• Tc1, from Tityus cambridgei, is the first member of a new subfamily of scorpion toxin that blocks K+‐channels

  2000cited by this paper
• NMR solution structure of butantoxin.

  2000cited by this paper
• Scorpion toxins specific for Na+-channels.

  1999cited by this paper
• TsTX-IV, a short chain four-disulfide-bridged neurotoxin from Tityus serrulatus venom which acts on Ca2+-activated K+ channels.

  1999cited by this paper
• A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.

  1999cited by this paper
• Peptide toxins as probes of ryanodine receptor structure and function.

  1998cited by this paper
• Folding motifs induced and stabilized by distinct cystine frameworks.

  1998cited by this paper
• Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin

  1998cited by this paper
• Membrane potential modulators: a thread of scarlet from plants to humans

  1998cited by this paper
• Protein folding coupled to disulphide bond formation.

  1997cited by this paper
• Protein folding coupled to disulphide bond formation.

  1997cited by this paper
• Toxins and genes isolated from scorpions of the genus Tityus.

  1997cited by this paper
• Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus.

  1996cited by this paper
• Tityustoxin K alpha blocks voltage-gated noninactivating K+ channels and unblocks inactivating K+ channels blocked by alpha-dendrotoxin in synaptosomes.

  1994cited by this paper
• Purification and characterization of chlorotoxin, a chloride channel ligand from the venom of the scorpion.

  1993cited by this paper
• Hydrophobic chromatography.

  1990cited by this paper
• Functional expression of Shaker K+ channels in a baculovirus-infected insect cell line.

  1990cited by this paper
• [27] Hydrophobic chromatography

  1990cited by this paper
• Purification and chemical characterization of the major toxins from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello

  1981cited by this paper
• Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

  1981cited by this paper
• Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.

  1977cited by this paper
• [9] Hydrophobic chromatography

  1974cited by this paper
• The turbidimetric assay of hyaluronidase.

  1949cited by this paper
• THE RÔLE OF THE MUCOID POLYSACCHARIDE (HYALURONIC ACID) IN THE VIRULENCE OF GROUP A HEMOLYTIC STREPTOCOCCI

  1944cited by this paper

• A Hydrolase-Rich Venom Beyond Neurotoxins: Integrative Functional Proteomic and Immunoreactivity Analyses Reveal Novel Peptides in the Amazonian Scorpion Brotheas amazonicus

  2026cites this paper
• Cvill6 and Cvill7: Potent and Selective Peptide Blockers of Kv1.2 Ion Channel Isolated from Mexican Scorpion Centruroides villegasi

  2025cites this paper
• Enzymatic characterization and proteomic profiling of venoms from the medically important Androctonus species

  2025cites this paper
• In vitro and in vivo antibacterial activity of TsAP-2 from Tityus stigmurus scorpion venom in multidrug-resistant strains and its NMR three-dimensional structure.

  2025cites this paper
• Transcriptomics-Informed Proteomics of Venom Glands and Crude Venom from Tityus cf. Asthenes from Panama: Enzymes, Proteins, Toxins, and Antimicrobial Peptides.

  2025cites this paper
• Molecular Diversity and Isoform Evolution in Tityus obscurus Venom: Insights from Proteomic Analysis

  2025cites this paper
• Revisiting toxins with transcriptomics-informed proteomics of venom glands and crude venom from Centruroides bicolor from Panama.

  2025cites this paper
• Unveiling Tst3, a Multi-Target Gating Modifier Scorpion α Toxin from Tityus stigmurus Venom of Northeast Brazil: Evaluation and Comparison with Well-Studied Ts3 Toxin of Tityus serrulatus

  2024influential citation
• Purification and Molecular Characterization of a Mammalian Neurotoxin as a Pharmaceutical Tool from the Venom of Iranian Scorpion Androctonus crassicauda

  2024cites this paper
• Whole transcriptome sequencing reveals the activity of the PLA2 family members in Androctonus crassicauda (Scorpionida: Buthidae) venom gland

  2024cites this paper
• Development and evaluation of a recombinant multi-epitopic protein (TsMEP) as an antigen candidate for Tityus serrulatus antivenom production.

  2024cites this paper
• Tityus stigmurus-Venom-Loaded Cross-Linked Chitosan Nanoparticles Improve Antimicrobial Activity

  2024cites this paper
• Proteomic analysis of the venom of Conus flavidus from Red Sea reveals potential pharmacological applications

  2024cites this paper
• The complex repertoire of Tityus spp. venoms: Advances on their composition and pharmacological potential of their toxins.

  2024cites this paper
• Exploring the Inter- and Intra-Specific Variability of Androctonus Scorpion Venoms

  2023cites this paper
• Beta-KTx14.3, a scorpion toxin, blocks the human potassium channel KCNQ1.

  2023cites this paper
• Unraveling and profiling Tityus bahiensis venom: Biochemical analyses of the major toxins.

  2023cites this paper
• Bioactive peptides from scorpion venoms: therapeutic scaffolds and pharmacological tools.

  2023cites this paper
• On the noxious black Amazonian scorpion, Tityus obscurus (Scorpiones, Buthidae): Taxonomic notes, biology, medical importance and envenoming treatment.

  2023cites this paper
• Comparative Proteomic Analysis of the Venoms from the Most Dangerous Scorpions in Morocco: Androctonus mauritanicus and Buthus occitanus

  2023cites this paper
• Modulation of hNav by Tst1, a β-toxin purified from the scorpion Tityus stigmurus.

  2022cites this paper
• Intraspecific differences in Androctunus crassicauda venom and envenomation symptoms

  2022cites this paper
• New insights about scorpion venom hyaluronidase; isoforms, expression and phylogeny

  2022cites this paper
• Toxinology in the proteomics era: a review on arachnid venom proteomics

  2022cites this paper
• CAP superfamily proteins from venomous animals: Who we are and what to do?

  2022cites this paper
• Acetylcholinesterase inhibitory potential of scorpion venom in Aedes aegypti (Diptera: Culicidae).

  2022cites this paper
• Exploring the biological activities and proteome of Brazilian scorpion Rhopalurus agamemnon venom.

  2021cites this paper
• Toxicosis of Snake, Scorpion, Honeybee, Spider, and Wasp Venoms: Part 1

  2021cites this paper
• Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications

  2021cites this paper
• Biology, venom composition, and scorpionism induced by brazilian scorpion Tityus stigmurus (Thorell, 1876) (Scorpiones: Buthidae): A mini-review.

  2020cites this paper
• NMR three-dimensional structure of the cationic peptide Stigmurin from Tityus stigmurus scorpion venom: in vitro antioxidant and in vivo antibacterial and healing activity.

  2020cites this paper
• Antimicrobial Activity of Hemolymph and Venom Obtained from Some Scorpion Species

  2020cites this paper
• Vulnerabilities and clinical manifestations in scorpion envenomations in Santarém, Pará, Brazil: a qualitative study.

  2020cites this paper
• Pioneering Study on Rhopalurus crassicauda Scorpion Venom: Isolation and Characterization of the Major Toxin and Hyaluronidase

  2020cites this paper
• Determination of hyaluronidase activity in Tityus spp. Scorpion venoms and its inhibition by Brazilian antivenoms.

  2019cites this paper
• Characterization, molecular modeling and phylogenetic analysis of a long mammalian neurotoxin from the venom of the Iranian scorpion Androctonus crassicauda

  2019cites this paper
• Heterologous expression and mutagenesis of recombinant Vespa affinis hyaluronidase protein (rVesA2)

  2019cites this paper
• J Venom Anim Toxins incl Trop Dis

  2019cites this paper
• Scorpion venom increases acetylcholine release by prolonging the duration of somatic nerve action potentials.

  2019cites this paper
• Biochemical and structural characterization of a protein complex containing a hyaluronidase and a CRISP-like protein isolated from the venom of the spider Acanthoscurria natalensis.

  2019cites this paper
• Proteome of fraction from Tityus serrulatus venom reveals new enzymes and toxins

  2019cites this paper
• Venom characterization of the Amazonian scorpion Tityus metuendus

  2018cites this paper
• Effects of Brazilian scorpion venoms on the central nervous system

  2018cites this paper
• Profiling the short, linear, non-disulfide bond-containing peptidome from the venom of the scorpion Tityus obscurus.

  2018cites this paper
• Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions

  2018cites this paper
• Heterologous expression of rTsHyal-1: the first recombinant hyaluronidase of scorpion venom produced in Pichia pastoris system

  2018cites this paper
• Determination of median effective dose (ED50) of scorpion antivenom against scorpion envenomation using a newly developed formula

  2018cites this paper
• Heterologous expression of rTsHyal-1: the first recombinant hyaluronidase of scorpion venom produced in Pichia pastoris system

  2018cites this paper
• A global accounting of medically significant scorpions: Epidemiology, major toxins, and comparative resources in harmless counterparts

  2018cites this paper
• Comparative analyses and implications for antivenom serotherapy of four Moroccan scorpion Buthus occitanus venoms: Subspecies tunetanus, paris, malhommei, and mardochei

  2017cites this paper
• Estudo clínico-epidemiológico, laboratorial e de vulnerabilidade dos acidentes escorpiônicos atendidos no Hospital Municipal de Santarém - Pará

  2016cites this paper
• Effects of Tityus stigmurus (Thorell 1876) (Scorpiones: Buthidae) venom in isolated perfused rat kidneys.

  2016cites this paper
• Scorpion Venom Gland Transcriptomics and Proteomics: An Overview

  2016cites this paper
• Venom from Opisthacanthus elatus scorpion of Colombia, could be more hemolytic and less neurotoxic than thought.

  2016cites this paper
• Scorpion maintenance in captivity for venom extraction in Costa Rica

  2016cites this paper
• Biotechnological Trends in Spider and Scorpion Antivenom Development

  2016cites this paper
• Scorpions maintenance in captivity for venom extraction purposes in Costa Rica.

  2016cites this paper
• Revealing the functional structure of a new PLA2 K49 from Bothriopsis taeniata snake venom employing automatic "de novo" sequencing using CID/HCD/ETD MS/MS analyses.

  2016cites this paper
• Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus ().

  2016cites this paper
• Non-disulfide-bridged peptides from Tityus serrulatus venom: Evidence for proline-free ACE-inhibitors.

  2016cites this paper
• Arachnids of medical importance in Brazil: main active compounds present in scorpion and spider venoms and tick saliva

  2015cites this paper
• Enzymatic analysis of venom from Cuban scorpion Rhopalurus junceus

  2015cites this paper
• Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology

  2015cites this paper
• Characterization of Am IT, an anti-insect β-toxin isolated from the venom of scorpion Androctonus mauretanicus.

  2015cites this paper
• General characterization of Tityus fasciolatus scorpion venom. Molecular identification of toxins and localization of linear B-cell epitopes.

  2015cites this paper
• Acute cerebellar dysfunction with neuromuscular manifestations after scorpionism presumably caused by Tityus obscurus in Santarém, Pará / Brazil.

  2015cites this paper
• Modern venom profiling: mining into scorpion venom biodiversity

  2015cites this paper
• Homology modeling, vasorelaxant and bradykinin-potentiating activities of a novel hypotensin found in the scorpion venom from Tityus stigmurus.

  2015cites this paper
• Potassium channel blocking peptide toxins from scorpion venom

  2015cites this paper
• Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion

  2015cites this paper
• SjAPI-2 is the first member of a new neurotoxin family with Ascaris-type fold and KCNQ1 inhibitory activity.

  2015cites this paper
• Snapshots of scorpion venomics

  2015cites this paper
• The transcriptome recipe for the venom cocktail of Tityus bahiensis scorpion.

  2015cites this paper
• A K⁺ channel blocking peptide from the Cuban scorpion Rhopalurus garridoi.

  2014cites this paper
• Overview of Scorpion Species from China and Their Toxins

  2014cites this paper
• The Mediterranean scorpion Mesobuthus gibbosus (Scorpiones, Buthidae): transcriptome analysis and organization of the genome encoding chlorotoxin-like peptides

  2014cites this paper
• A first exploration of the venom of the Buthus occitanus scorpion found in southern France.

  2014cites this paper
• Structure, Molecular Modeling, and Function of the Novel Potassium Channel Blocker Urotoxin Isolated from the Venom of the Australian Scorpion Urodacus yaschenkoi

  2014cites this paper
• Antarease-like Zn-metalloproteases are ubiquitous in the venom of different scorpion genera.

  2014cites this paper
• Proteomic analysis of the venom from the scorpion Mesobuthus martensii.

  2014cites this paper
• Influence of post-starvation extraction time and prey-specific diet in Tityus serrulatus scorpion venom composition and hyaluronidase activity.

  2014cites this paper
• Scorpionism and dangerous species of Brazil

  2014cites this paper
• Venom Yield, Regeneration, and Composition in the Centipede Scolopendra Polymorpha

  2014cites this paper
• MOL090183 28..41

  2014influential citation
• Scorpionism and Dangerous Scorpions in Central America and the Caribbean Region

  2013cites this paper
• Moving pieces in a venomic puzzle: unveiling post-translationally modified toxins from Tityus serrulatus.

  2013cites this paper
• Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae.

  2013cites this paper
• The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas

  2013cites this paper
• K + channel blocking peptide from the Cuban scorpion hopalurus garridoi odolfo

  2013influential citation
• Enzymatic properties of venoms from Brazilian scorpions of Tityus genus and the neutralisation potential of therapeutical antivenoms.

  2013cites this paper
• Análise dos componentes proteolíticos e peptídicos do veneno do e scorpião Tityus serrulatus

  2013cites this paper
• Chapter 59 – Scorpion Peptides

  2013cites this paper
• Mass Fingerprinting of the Venom and Transcriptome of Venom Gland of Scorpion Centruroides tecomanus

  2013cites this paper
• Scorpion venom components that affect ion-channels function.

  2013cites this paper
• Another record of significant regional variation in toxicity of Tityus serrulatus venom in Brazil: a step towards understanding the possible role of sodium channel modulators.

  2013cites this paper
• Venom proteomic and venomous glands transcriptomic analysis of the Egyptian scorpion Scorpio maurus palmatus (Arachnida: Scorpionidae).

  2013cites this paper
• Structure, function, and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.

  2012cites this paper
• Turkish scorpion Buthacus macrocentrus: general characterization of the venom and description of Bu1, a potent mammalian Na⁺-channel α-toxin.

  2012cites this paper
• Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: implication for proteome evolution of scorpion venom arsenal.

  2012cites this paper
• Vm 24 , a Natural Immunosuppressive Peptide , Potently and Selectively Blocks Kv 1 . 3 Potassium Channels of Human T Cells

  2012cites this paper