Adrenomedullin stimulates DNA synthesis and cell proliferation via elevation of cAMP in Swiss 3T3 cells

No abstract is available for this paper.

• Publication year

  1996

• Venue

  FEBS Letters

• Publication date

  1996-01-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0014-5793(95)01427-6PMID 8549809
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Oxford textbook of oncology

  1996cited by this paper
• The human CCKB/gastrin receptor transfected into rat1 fibroblasts mediates activation of MAP kinase, p74raf-1 kinase, and mitogenesis.

  1995cited by this paper
• Adrenomedullin and calcitonin gene-related peptide interact with the same receptor in cultured human neuroblastoma SK-N-MC cells.

  1995cited by this paper
• Cloning and Expression of cDNA Encoding a Rat Adrenomedullin Receptor (*)

  1995cited by this paper
• Adrenomedullin Stimulates Two Signal Transduction Pathways, cAMP Accumulation and Ca2+ Mobilization, in Bovine Aortic Endothelial Cells (*)

  1995cited by this paper
• Dissociation of cAMP-stimulated Mitogenesis from Activation of the Mitogen-activated Protein Kinase Cascade in Swiss 3T3 Cells (*)

  1995cited by this paper
• Convergent signalling in the action of integrins, neuropeptides, growth factors and oncogenes.

  1995cited by this paper
• An abundant and specific binding site for the novel vasodilator adrenomedullin in the rat.

  1995cited by this paper
• Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma

  1994cited by this paper
• Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds.

  1993cited by this paper
• Bombesin, vasopressin, and endothelin rapidly stimulate tyrosine phosphorylation of the focal adhesion-associated protein paxillin in Swiss 3T3 cells.

  1993cited by this paper
• Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide.

  1993cited by this paper
• Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma.

  1993cited by this paper
• Molecular identification of binding sites for calcitonin gene-related peptide (CGRP) and islet amyloid polypeptide (IAPP) in mammalian lung: species variation and binding of truncated CGRP and IAPP.

  1993cited by this paper
• Growth factors and cell proliferation.

  1992cited by this paper
• Increased mitogenic responsiveness of Swiss 3T3 cells expressing constitutively active Gs alpha.

  1990cited by this paper
• KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II.

  1990cited by this paper
• Temporal relationship between inositol polyphosphate formation and increases in cytosolic Ca2+ in quiescent 3T3 cells stimulated by platelet‐derived growth factor, bombesin and vasopressin.

  1988cited by this paper
• A family of receptors coupled to guanine nucleotide regulatory proteins.

  1987cited by this paper
• Early signals in the mitogenic response.

  1986cited by this paper
• Bombesin stimulation of DNA synthesis and cell division in cultures of Swiss 3T3 cells.

  1983cited by this paper
• Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.

  1978cited by this paper

• Aflatoxin B1 targeted gene expression profiles in human placental primary trophoblast cells

  2022influential citation
• Targeting Adrenomedullin in Oncology: A Feasible Strategy With Potential as Much More Than an Alternative Anti-Angiogenic Therapy

  2021cites this paper
• novel angiogenic peptides in breast cancer

  2019cites this paper
• Adrenomedullin: A novel peptide hormone: A review

  2017cites this paper
• Adrenomedullin: A potential therapeutic target for retinochoroidal disease.

  2016cites this paper
• Novel Functions of Adrenomedullin, Receptor Activity-Modifying Protein 2, and Gpr182 in Cardiovascular Disease and Cancer

  2016cites this paper
• Adrenomedullin Promotes the Proliferation and Inhibits Apoptosis of Dental Pulp Stem Cells Involved in Divergence Pathways.

  2016cites this paper
• Adrenomedullin in Vascular Endothelial Injury and Combination Therapy: Time for a New Paradigm.

  2015cites this paper
• The action of CGRP and SP on cultured skin fibroblasts

  2014cites this paper
• Señalización de la adrenomedulina en el vermis del cerebelo de la rata (adrenomedullin signaling in rat cerebellar vermis)

  2014cites this paper
• Regulation and Neutralisation of Adrenomedullin in Cancer

  2014cites this paper
• Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin.

  2013cites this paper
• Adrenomedullin as a Novel Promising Therapeutic Approach

  2013cites this paper
• Short-term hypoxia/reoxygenation activates the angiogenic pathway in rat caudate putamen

  2013cites this paper
• Characterisation of the Molecular Mechanisms Regulating the Signalling and Post-endocytic sorting of the Receptors for Calcitonin Gene-Related Peptide and Adsenomedullin

  2013cites this paper
• Neural Stem Cells in the Adult Brain: From Benchside to Clinic

  2012cites this paper
• Signaling Pathways Induced by G-protein-coupled Receptors

  2012cites this paper
• Adrenomedullin as a Growth and Cell Fate Regulatory Factor for Adult Neural Stem Cells

  2012cites this paper
• Sustained-release adrenomedullin ointment accelerates wound healing of pressure ulcers.

  2011cites this paper
• La adrenomedulina: un péptido multifuncional

  2011cites this paper
• Rôle de l'adrénomédulline dans la néoangiogenèse et l'invasion tumorale

  2011cites this paper
• Adrenomedullin and its expression in cancers and bone. A literature review.

  2010cites this paper
• Lack of adrenomedullin affects growth and differentiation of adult neural stem/progenitor cells

  2010cites this paper
• Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation

  2010cites this paper
• Adrenomedullin in dental tissues

  2010cites this paper
• Circulating hormone adrenomedullin and its binding protein protect neural cells from hypoxia-induced apoptosis.

  2009cites this paper
• Adrenomedullin inhibits connective tissue growth factor expression, extracellular signal-regulated kinase activation and renal fibrosis.

  2008cites this paper
• Mitogenic signaling pathways induced by G protein‐coupled receptors

  2007influential citation
• Antimicrobial Peptides and Acne

  2007cites this paper
• Adrenomedullin is induced by hypoxia and enhances pancreatic cancer cell invasion

  2007cites this paper
• Stimulation of fibroblast proliferation by neokyotorphin requires Ca2+ influx and activation of PKA, CaMK II and MAPK/ERK

  2007cites this paper
• Differentiation of the HaCaT keratinocyte cell line: modulation by adrenomedullin

  2006cites this paper
• Expression of adrenomedullin in adipose tissue of lean and obese women.

  2006cites this paper
• Pathophysiologic and therapeutic implications of adrenomedullin in cardiovascular disorders.

  2006cites this paper
• Adrenomedullin and Endothelin-1: Two New Growth Factors for In Vitro Expansion of Hematopoietic Cord Blood Cells

  2006cites this paper
• Adrenomedullin: a tumor progression factor via angiogenic control.

  2006cites this paper
• [Role of adrenomedullin in glioblastomas growth].

  2005cites this paper
• Adrenomedullin stimulates nitric oxide release from SK-N-SH human neuroblastoma cells by modulating intracellular calcium mobilization.

  2005cites this paper
• Adrenomedullin Receptor and Signal Transduction

  2005cites this paper
• Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities.

  2005cites this paper
• Invasion et angiogenèse dans les gliomes : rôle de l'adrénomédulline : Les tumeurs gliales

  2005cites this paper
• Maturation of the expression of adrenomedullin, endothelin-1 and nitric oxide synthases in adipose tissues from childhood to adulthood

  2005cites this paper
• The contractile phenotype of peritubular smooth muscle cells is locally controlled: possible implications in male fertility.

  2005cites this paper
• Adrenomedullin affects two signal transduction pathways and the migration in retinal pigment epithelial cells.

  2004cites this paper
• Adrenomedullin signals through NF‐κB in epithelial cells

  2004cites this paper
• Expression of adrenomedullin and proadrenomedullin N-terminal 20 peptide in PC12 cells after exposure to nerve growth factor.

  2004cites this paper
• The pharmacology of adrenomedullin receptors and their relationship to CGRP receptors

  2004cites this paper
• Adrenomedullin: Multiple functions in human pregnancy

  2004cites this paper
• Adrenomedullin and natriuretic peptides in cardiac hypertrophy : regulation of gene expression and interactions with angiotensin II

  2004cites this paper
• Hormones of the Cardiovascular System

  2004cites this paper
• Adrenomedullin signals through NF-kappaB in epithelial cells.

  2004cites this paper
• ADRENOMEDULLIN AND NATRIURETIC PEPTIDES IN CARDIAC HYPERTROPHY

  2004cites this paper
• Regulation of cell growth and apoptosis by adrenomedullin.

  2003cites this paper
• Adrenomedullin Reduces VEGF-Induced Endothelial Adhesion Molecules and Adhesiveness Through a Phosphatidylinositol 3′-Kinase Pathway

  2003cites this paper
• Adrenomedullin is an autocrine/paracrine growth factor for rat vascular smooth muscle cells.

  2003cites this paper
• Human skin keratinocytes and fibroblasts express adrenomedullin and its receptors, and adrenomedullin enhances their growth in vitro by stimulating proliferation and inhibiting apoptosis.

  2003cites this paper
• Mediadores vasoactivos producidos por macrófagos peritoneales de pacientes cirróticos. Implicaciones fisiopatológicas.

  2003cites this paper
• CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22–52, CGRP8–37 and BIBN4096BS

  2003cites this paper
• Adrenomedullin in the eye.

  2003cites this paper
• Decreased expression of adrenomedullin during adipocyte-differentiation of 3T3-L1 cells.

  2003cites this paper
• Adrenomedullin: expression and possible role in human skin and hair growth

  2003cites this paper
• Regulation of Adrenomedullin Signaling in Kidney Interstitial Fibroblasts

  2003cites this paper
• Adrenomedullin and endocrine disorders.

  2003cites this paper
• Adrenomedullin inhibits pressure-induced mesangial MCP-1 expression through activation of protein kinase A.

  2003cites this paper
• Suppression of cytokine-induced expression of adrenomedullin and endothelin-1 by dexamethasone in T98G human glioblastoma cells.

  2003cites this paper
• Adrenomedullin promotes proliferation and migration of cultured endothelial cells.

  2003cites this paper
• Coexpression of calcitonin receptor-like receptor and receptor activity-modifying protein 2 or 3 mediates the antimigratory effect of adrenomedullin.

  2003cites this paper
• Expression of urotensin II and its receptor in adrenal tumors and stimulation of proliferation of cultured tumor cells by urotensin II.

  2003cites this paper
• Adrenomedulin from a Pheochromocytoma to the Eye : Implications of the Adrenomedulin Research for Endocrinology in the 21 st Century

  2003cites this paper
• Adrenomedullin stimulates proliferation and inhibits apoptosis of immature rat thymocytes cultured in vitro.

  2003cites this paper
• Elevated Adrenomedullin in the Vitreous of Patients with Diabetic Retinopathy

  2003cites this paper
• Adrenocortical peptides: autocrine or paracrine regulators for the steroid hormone secretion or the cell proliferation?

  2003cites this paper
• Regulation of adrenomedullin expression and release

  2002cites this paper
• Differential induction of early response genes by adrenomedullin and transforming growth factor-beta1 in human lung cancer cells.

  2002cites this paper
• Paracrine/autocrine function of adrenomedullin in peripheral nerves of rats.

  2002cites this paper
• Protective effect of adrenomedullin in mannitol-induced apoptosis

  2002cites this paper
• Adrenomedullin: receptor and signal transduction.

  2002cites this paper
• Cell and molecular biology of the multifunctional peptide, adrenomedullin.

  2002cites this paper
• Resistance to Neointimal Hyperplasia and Fatty Streak Formation in Mice With Adrenomedullin Overexpression

  2002cites this paper
• Differential expression of adrenomedullin and its receptors in newborn and adult rat thymus.

  2002cites this paper
• Adrenomedullin functions as an important tumor survival factor in human carcinogenesis

  2002cites this paper
• Adrenocortical Peptides: Autocrine or Paracrine Regulators for the Steroid Hormone Secretion or the Cell Proliferation?

  2002cites this paper
• Saturation of adrenomedullin receptors plays an important role in reducing pulmonary clearance of adrenomedullin during the late stage of sepsis.

  2002cites this paper
• Adrenomedullin in mammalian embryogenesis

  2002cites this paper
• Distribution and possible function of an adrenomedullin-like peptide in the developing chick limb bud.

  2002cites this paper
• Hypoxic induction of adrenomedullin in cultured human umbilical vein endothelial cells

  2001cites this paper
• A review of the biological properties and clinical implications of adrenomedullin and proadrenomedullin N-terminal 20 peptide (PAMP), hypotensive and vasodilating peptides.

  2001cites this paper
• Proadrenomedullin-derived peptides in the paracrine control of the hypothalamo-pituitary-adrenal axis.

  2001cites this paper
• Adrenomedullin from a pheochromocytoma to the eye: implications of the adrenomedullin research for endocrinology in the 21st century.

  2001cites this paper
• Adrenomedullin stimulates DNA synthesis of rat adrenal zona glomerulosa cells through activation of the mitogen-activated protein kinase-dependent cascade

  2001cites this paper
• Gene expression of adrenomedullin, leptin, their receptors and neuropeptide Y in hormone‐secreting and non‐functioning pituitary adenomas, meningiomas and malignant intracranial tumours in humans

  2001cites this paper
• Interaction between monocytes and vascular endothelial cells induces adrenomedullin production.

  2001cites this paper
• Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells.

  2001cites this paper
• Adrenomedullin receptors: molecular identity and function.

  2001cites this paper
• Induction of adrenomedullin by hypoxia in cultured retinal pigment epithelial cells.

  2001cites this paper
• Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells.

  2001cites this paper
• Cancer and diabetes: two pathological conditions in which adrenomedullin may be involved.

  2001cites this paper
• Proadrenomedullin-derived peptides as autocrine-paracrine regulators of cell growth.

  2001cites this paper
• Alternative splicing of the proadrenomedullin gene results in differential expression of gene products.

  2001cites this paper
• Adrenomedullin, a new peptide, in patients with insulinoma.

  2001cites this paper