miRNAs and cancer: an epigenetics view.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Molecular Aspects of Medicine

• Publication date

  2013-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.mam.2012.06.005PMID 22771542PMCID PMC5791883
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Polycombs and microRNA-223 regulate human granulopoiesis by transcriptional control of target gene expression.

  2012influential reference
• Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia.

  2012cited by this paper
• Clinical outcome prediction by microRNAs in human cancer: a systematic review.

  2012cited by this paper
• Enhancer of zeste homolog 2 epigenetically silences multiple tumor suppressor microRNAs to promote liver cancer metastasis

  2012cited by this paper
• miR-155 regulates IFN-γ production in natural killer cells.

  2012cited by this paper
• MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review

  2012influential reference
• Mapping the regulatory sequences controlling 93 breast cancer-associated miRNA genes leads to the identification of two functional promoters of the Hsa-mir-200b cluster, methylation of which is associated with metastasis or hormone receptor status in advanced breast cancer

  2012cited by this paper
• Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma

  2012cited by this paper
• MicroRNA‐224 is up‐regulated in hepatocellular carcinoma through epigenetic mechanisms

  2012cited by this paper
• Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.

  2012cited by this paper
• Role of miR-155 in breast cancer.

  2012cited by this paper
• miR-155 regulates HGAL expression and increases lymphoma cell motility.

  2012cited by this paper
• Epigenetic regulation of miRNA genes in acute leukemia

  2012cited by this paper
• DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer

  2011cited by this paper
• miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer.

  2011cited by this paper
• microRNAs: Master regulators as potential therapeutics in cancer.

  2011cited by this paper
• Epigenetic Silencing of miR-203 Upregulates SNAI2 and Contributes to the Invasiveness of Malignant Breast Cancer Cells.

  2011cited by this paper
• MicroRNAs Regulate Dendritic Cell Differentiation and Function

  2011cited by this paper
• Epigenetic regulation of microRNAs in cancer: an integrated review of literature.

  2011cited by this paper
• Combinatorial effects of microRNAs to suppress the Myc oncogenic pathway.

  2011influential reference
• The histone deacetylase 4/SP1/microrna‐200a regulatory network contributes to aberrant histone acetylation in hepatocellular carcinoma

  2011cited by this paper
• The oncogenic and tumour suppressive roles of microRNAs in cancer and apoptosis.

  2011cited by this paper
• MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma

  2011cited by this paper
• Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer.

  2011cited by this paper
• miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells*

  2011cited by this paper
• Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

  2011cited by this paper
• miRNA response to DNA damage.

  2011cited by this paper
• Coordinated regulation of polycomb group complexes through microRNAs in cancer.

  2011cited by this paper
• Jumonji/ARID1 B (JARID1B) Protein Promotes Breast Tumor Cell Cycle Progression through Epigenetic Repression of MicroRNA let-7e*

  2011cited by this paper
• Competitive Interactions of Cancer Cells and Normal Cells via Secretory MicroRNAs*

  2011cited by this paper
• MicroRNAs miR-199a-5p and -3p target the Brm subunit of SWI/SNF to generate a double-negative feedback loop in a variety of human cancers.

  2011influential reference
• Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants.

  2011cited by this paper
• Transcriptional gene silencing in mammalian cells by miRNA mimics that target gene promoters

  2011influential reference
• MicroRNAs and the cell cycle.

  2011cited by this paper
• Functional complementation between transcriptional methylation regulation and post-transcriptional microRNA regulation in the human genome

  2011cited by this paper
• Unraveling the Mystery of Cancer by Secretory microRNA: Horizontal microRNA Transfer between Living Cells

  2011cited by this paper
• Roles of the Polycomb group proteins in stem cells and cancer

  2011cited by this paper
• Upregulation of Cyclin B1 by miRNA and its implications in cancer

  2011cited by this paper
• Metastamirs: a stepping stone towards improved cancer management

  2011cited by this paper
• MicroRNAs and epigenetics

  2011cited by this paper
• Role of microRNA-155 in autoimmunity.

  2011cited by this paper
• Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

  2010cited by this paper
• OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma

  2010cited by this paper
• MicroRNA‐dependent regulation of DNA methyltransferase‐1 and tumor suppressor gene expression by interleukin‐6 in human malignant cholangiocytes

  2010influential reference
• miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts.

  2010cited by this paper
• The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?

  2010cited by this paper
• Down‐regulated microRNA‐152 induces aberrant DNA methylation in hepatitis B virus–related hepatocellular carcinoma by targeting DNA methyltransferase 1

  2010cited by this paper
• Targeting microRNAs in cancer: rationale, strategies and challenges

  2010cited by this paper
• MicroRNAs and metastasis: little RNAs go a long way.

  2010cited by this paper
• The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia.

  2010cited by this paper
• Interplay between microRNAs and the epigenetic machinery: an intricate network.

  2010cited by this paper
• Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells.

  2010influential reference
• MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis.

  2010cited by this paper
• Metastasis-related miRNAs, active players in breast cancer invasion, and metastasis

  2010cited by this paper
• mir-17-92, a cluster of miRNAs in the midst of the cancer network.

  2010cited by this paper
• The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases.

  2010cited by this paper
• Epigenetics, miRNAs, and human cancer: a new chapter in human gene regulation

  2009cited by this paper
• miR-449a targets HDAC-1 and induces growth arrest in prostate cancer

  2009cited by this paper
• MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.

  2009cited by this paper
• Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells

  2009cited by this paper
• Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model.

  2009cited by this paper
• Regression of murine lung tumors by the let-7 microRNA

  2009cited by this paper
• Mir-214-dependent regulation of the polycomb protein Ezh2 in skeletal muscle and embryonic stem cells.

  2009cited by this paper
• miR-155: On the Crosstalk Between Inflammation and Cancer

  2009cited by this paper
• Predicting potential miRNA target sites within gene promoters.

  2009cited by this paper
• The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

  2009influential reference
• miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A.

  2009cited by this paper
• miR-15a and miR-16 are implicated in cell cycle regulation in a Rb-dependent manner and are frequently deleted or down-regulated in non-small cell lung cancer.

  2009cited by this paper
• MicroRNAs in cancer.

  2009cited by this paper
• MicroRNAs in Cancer.

  2009cited by this paper
• The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.

  2009cited by this paper
• MYC stimulates EZH2 expression by repression of its negative regulator miR-26a.

  2008cited by this paper
• MicroRNA-373 induces expression of genes with complementary promoter sequences

  2008cited by this paper
• MicroRNAs accurately identify cancer tissue origin

  2008cited by this paper
• Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.

  2008cited by this paper
• MicroRNA in cancer prognosis.

  2008cited by this paper
• Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal.

  2008cited by this paper
• The let-7 family of microRNAs.

  2008cited by this paper
• A microRNA DNA methylation signature for human cancer metastasis

  2008cited by this paper
• miRiad roles for the miR-17-92 cluster in development and disease.

  2008cited by this paper
• MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells.

  2008cited by this paper
• Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

  2008cited by this paper
• MicroRNAs as potential cancer therapeutics

  2008cited by this paper
• miR-148 targets human DNMT3b protein coding region.

  2008cited by this paper
• Epigenetic inactivation of microRNA gene hsa‐mir‐9‐1 in human breast cancer

  2008cited by this paper
• miRNAs, 'stemness' and skin.

  2008cited by this paper
• MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer

  2008cited by this paper
• NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma.

  2008cited by this paper
• Programmed Cell Death 4 (PDCD4) Is an Important Functional Target of the MicroRNA miR-21 in Breast Cancer Cells*

  2008cited by this paper
• MicroRNA-directed transcriptional gene silencing in mammalian cells

  2008influential reference
• Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.

  2008cited by this paper
• Regulation of the Germinal Center Response by MicroRNA-155

  2007cited by this paper
• Epigenetic gene silencing in cancer: the DNA hypermethylome.

  2007influential reference
• MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

  2007influential reference
• The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.

  2007cited by this paper
• MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer.

  2007cited by this paper
• Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.

  2007cited by this paper
• Methylation of Human MicroRNA Genes in Normal and Neoplastic Cells

  2007influential reference
• Strategies for silencing human disease using RNA interference

  2007cited by this paper
• Transcripts Targeted by the MicroRNA-16 Family Cooperatively Regulate Cell Cycle Progression

  2007cited by this paper

• Cytokines, Signaling and Epigenetic Mechanisms: Shaping the Acute Lymphoblastic Leukemia Microenvironment

  2026cites this paper
• Single Nucleotide Polymorphisms within the microRNA Binding Site of SET8 Modify Ankylosing Spondylitis Risk

  2025cites this paper
• Comparative Study of the Effects of Docosahexaenoic Acid, Linoleic Acid, and Taxol in Decreasing the Expression of miR-10b, and miR-20a OncomiRs, and their Target Major Histocompatibility Complex Class I Chain-Related Proteins A (MICA) in Triple-Negative Metastatic Breast Cancer Cell Line

  2024cites this paper
• Non‐coding RNAs and their potential exploitation in cancer therapy‐related cardiotoxicity

  2024cites this paper
• Non-Mutational Key Features in the Biology of Thymomas

  2024cites this paper
• miRNA‐21 Inhibitor‐Loaded Cationic Liposomes Development using the Quality by Design Approach

  2024cites this paper
• miRNA Expression Profiling in G1 and G2 Pancreatic Neuroendocrine Tumors

  2024cites this paper
• Progress in Precision Medicine for Head and Neck Cancer

  2024cites this paper
• Single nucleotide polymorphisms in the Dicer gene modify the risk of systemic lupus erythematosus

  2024cites this paper
• The complex nature of lncRNA-mediated chromatin dynamics in multiple myeloma

  2023cites this paper
• Non-coding RNAs/DNMT3B axis in human cancers: from pathogenesis to clinical significance

  2023cites this paper
• MicroRNAs as clinical tools for diagnosis, prognosis, and therapy in prostate cancer

  2023cites this paper
• Bifunctional Y-shaped probe combined with dual amplification for colorimetric sensing and molecular logic operation of two miRNAs.

  2023cites this paper
• Differential Expression of Non-Coding RNAs in Stem Cell Development and Therapeutics of Bone Disorders

  2023cites this paper
• Recent Advances in Drug Discovery Toxicology

  2023cites this paper
• From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response

  2023cites this paper
• Apoptosis evasion via long non-coding RNAs in colorectal cancer

  2022cites this paper
• A Quality by Design Approach in Pharmaceutical Development of Non-Viral Vectors with a Focus on miRNA

  2022cites this paper
• Histone Modifications and Non-Coding RNAs: Mutual Epigenetic Regulation and Role in Pathogenesis

  2022cites this paper
• MiR‐548k suppresses apoptosis in breast cancer cells by affecting PTEN/PI3K/AKT signaling pathway

  2022cites this paper
• Biomarkers (mRNAs and Non-Coding RNAs) for the Diagnosis and Prognosis of Colorectal Cancer – From the Body Fluid to Tissue Level

  2021cites this paper
• Targeting the epigenome in in-stent restenosis: from mechanisms to therapy

  2021cites this paper
• miRNAs as attractive diagnostic and therapeutic targets for Familial Mediterranean Fever

  2021cites this paper
• miR-340-5p inhibits pancreatic acinar cell inflammation and apoptosis via targeted inhibition of HMGB1.

  2021cites this paper
• Different bisphenols induce non-monotonous changes in miRNA expression and LINE-1 methylation in two cell lines

  2021cites this paper
• An update on genotoxic and epigenetic studies of fumonisin B1

  2021cites this paper
• Dynamics of biomarkers across the stages of traumatic spinal cord injury - implications for neural plasticity and repair

  2021cites this paper
• How to Differentiate Benign from Malignant Adrenocortical Tumors?

  2021cites this paper
• Molecular epigenetic dynamics in breast carcinogenesis

  2021cites this paper
• Epigenetic Deregulation of Apoptosis in Cancers

  2021cites this paper
• MicroRNA as a Novel Biomarker in the Diagnosis of Head and Neck Cancer

  2021cites this paper
• Progress in human embryonic stem cell research and aging

  2021cites this paper
• Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends

  2021cites this paper
• Epigenetic modifications in acute lymphoblastic leukemia: From cellular mechanisms to therapeutics.

  2020cites this paper
• N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool

  2020cites this paper
• MicroRNAs: Diverse Mechanisms of Action and Their Potential Applications as Cancer Epi-Therapeutics

  2020cites this paper
• Non-Coding RNAs in Adrenocortical Cancer: From Pathogenesis to Diagnosis

  2020cites this paper
• İnsan Hastalıklarında Epigenetiğin Rolüne Klinik Bakış

  2020cites this paper
• SET protein modulates H4 histone methylation status and regulates miR-137 level in oral squamous cell carcinoma.

  2020cites this paper
• A Polymorphism at the microRNA Binding Site in the 3′ Untranslated Region of KRT81 Is Associated with Breast Cancer

  2020cites this paper
• MiR-181a enhances drug sensitivity of mixed lineage leukemia-rearranged acute myeloid leukemia by increasing poly(ADP-ribose) polymerase1 acetylation

  2020cites this paper
• Regulatory Mechanisms of Epigenetic miRNA Relationships in Human Cancer and Potential as Therapeutic Targets

  2020cites this paper
• Epigenetics/Epigenomics and Prevention of Early Stages of Cancer by Isothiocyanates

  2020cites this paper
• Uncovering epigenetic landscape: a new path for biomarkers identification and drug development

  2020cites this paper
• 表观遗传修饰调控微小RNA表达在肺癌中的研究进展

  2020cites this paper
• Amplified visual detection of microRNA-378 through a T4 DNA ligase-mediated circular template specific to target and target-triggering rolling circle amplification

  2019cites this paper
• Epigenetic modifications associated with in utero exposure to endocrine disrupting chemicals BPA, DDT and Pb

  2019cites this paper
• Epigenetic Drivers of Resveratrol-Induced Suppression of Mammary Carcinogenesis: Addressing miRNAs, Protein, mRNA, and DNA Methylation

  2019cites this paper
• A fungal milRNA mediates epigenetic repression of a virulence gene in Verticillium dahliae

  2019cites this paper
• Comparison of plasma and urinary microRNA-483-5p for the diagnosis of adrenocortical malignancy.

  2019cites this paper
• MicroRNA-26a: An Emerging Regulator of Renal Biology and Disease

  2019cites this paper
• Epigenetic Gene Regulation by Dietary Compounds in Cancer Prevention

  2019cites this paper
• Le psychotraumatisme s’inscrit dans l’ADN et peut se transmettre sur plusieurs générations. Apports de la méditation de pleine conscience dans les troubles de l’anxiété et l’état de stress post-traumatique

  2019cites this paper
• miR‑29 promoter and enhancer methylation identified by pyrosequencing in Burkitt lymhoma cells: Interplay between MYC and miR‑29 regulation.

  2019cites this paper
• MicroRNA‐mediated drug resistance in ovarian cancer

  2019cites this paper
• Oral Carcinogenesis and Malignant Transformation

  2019cites this paper
• High expression of microRNA-199a-5p is associated with superior clinical outcomes in patients with locally advanced rectal cancer

  2019cites this paper
• FOXS1 is regulated by GLI1 and miR-125a-5p and promotes cell proliferation and EMT in gastric cancer

  2019cites this paper
• Circulating miRNA Expression Profiling in Primary Aldosteronism

  2019cites this paper
• The Regulatory Roles of Non-coding RNAs in Angiogenesis and Neovascularization From an Epigenetic Perspective

  2019cites this paper
• α-Aminoisobutyric acid-containing amphipathic helical peptide-cyclic RGD conjugation as a potential drug delivery system for microRNA replacement therapy in vitro.

  2019cites this paper
• Scientific Advances in the Diagnosis of Emerging and Reemerging Viral Human Pathogens

  2019cites this paper
• Electrochemical Nano-biosensors as Novel Approach for the Detection of Lung Cancer-related MicroRNAs.

  2019cites this paper
• GKN1 expression in gastric cancer cells is negatively regulated by miR-544a.

  2019cites this paper
• The effects of dietary polyunsaturated fatty acids on miR-126 promoter DNA methylation status and VEGF protein expression in the colorectal cancer cells

  2018cites this paper
• Functions and epigenetic aspects of miR-15/16: Possible future cancer therapeutics

  2018cites this paper
• Interaction of Various Cancer Tissue Components : Their Role in Tumor Development and Therapy Resistance

  2018cites this paper
• Epigenetics/Epigenomics of Olive Oil and the Mediterranean Diet

  2018cites this paper
• Biochemical and molecular perspectives on polyphenol rich food, probiotic food, and their combination

  2018cites this paper
• Melt curve analysis for interpretation of MicroRNAs' gene expression data in foods

  2018cites this paper
• Methylation status of Vitamin D receptor gene promoter in adrenocortical carcinoma

  2018cites this paper
• miR-126 promotes the growth and proliferation of leukemia stem cells by targeting DNA methyltransferase 1.

  2018cites this paper
• Faculteit Geneeskunde en Levenswetenschappen School voor Levenswetenschappen master in de biomedische wetenschappen

  2018influential citation
• Cell Cycle Regulation of Stem Cells by MicroRNAs

  2018cites this paper
• Pathogenic and diagnostic roles of microRNAs in adrenocortical tumours

  2018cites this paper
• MiR-29 silencing modulates the expression of target genes related to proliferation, apoptosis and methylation in Burkitt lymphoma cells

  2018cites this paper
• From chemo-prevention to epigenetic regulation: The role of isothiocyanates in skin cancer prevention.

  2018cites this paper
• MicroRNA Expression Profiling in Adrenal Myelolipoma

  2018cites this paper
• miRNAs as biomarkers and for the early detection of non-small cell lung cancer (NSCLC).

  2018cites this paper
• MicroRNAs’ Gene Expression Technology for the Evaluation of Disease Modulation by Mild Nutrients

  2018cites this paper
• Noncoding RNA in NK cells

  2018cites this paper
• MicroRNA‐326 and microRNA‐200c: Two novel biomarkers for diagnosis and prognosis of pediatric acute lymphoblastic leukemia

  2018cites this paper
• Circulating MiRNA-21 and programed cell death (PDCD) 4 gene expression in hepatocellular carcinoma (HCC) in Egyptian patients

  2017cites this paper
• A new insight on reciprocal relationship between microRNA expression and epigenetic modifications in human lung cancer

  2017cites this paper
• Thymic Epithelial Tumors phenotype relies on miR-145-5p epigenetic regulation

  2017cites this paper
• Head and Neck Cancer: Epidemiology and Role of MicroRNAs

  2017cites this paper
• Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer

  2017cites this paper
• Effects of BPA on female reproductive function: The involvement of epigenetic mechanism.

  2017cites this paper
• A Hybrid Feature Selection Method Based on Symmetrical Uncertainty and Support Vector Machine for High-Dimensional Data Classification

  2017cites this paper
• miRNAs in Normal and Malignant Hematopoiesis

  2017cites this paper
• Suppression subtractive hybridization identified differentially expressed genes in colorectal cancer: microRNA-451a as a novel colorectal cancer–related gene

  2017cites this paper
• miRNA genetic variants: As potential diagnostic biomarkers for oral cancer.

  2017cites this paper
• Role of Melt Curve Analysis in Interpretation of Nutrigenomics' MicroRNA Expression Data.

  2017cites this paper
• Expression of hsa-miR-9 and MYC Copy Number Variation in Hereditary Diffuse Gastric Cancer.

  2017cites this paper
• Potential relevance of microRNAs in inter-species epigenetic communication, and implications for disease pathogenesis

  2017cites this paper
• Exploration de l’impact de l’exposition chronique et faibles doses de facteurs environnementaux sur les cellules pré-cancéreuses mammaires MCF10AT1

  2017cites this paper
• MicroRNA-29 b regulates osteopontin dependent proliferation function and cell cycle in esophageal cancer lines

  2017cites this paper
• Keringő mikroRNS-ek az endokrin daganatok diagnosztikájában

  2017cites this paper
• MicroRNAs and Epigenetics

  2017cites this paper
• [Circulating microRNAs in the diagnostics of endocrine neoplasms].

  2017cites this paper