Postburn Hypermetabolism: Past, Present, and Future

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Burn Care & Research

• Publication date

  2016-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/BCR.0000000000000265PMID 26132047PMCID PMC4691431
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Respiratory muscle strength and maximal voluntary ventilation in undernourished patients.

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• A randomized trial of hyperglycemic control in pediatric intensive care.

  2014cited by this paper
• Leukocyte Infiltration and Activation of the NLRP3 Inflammasome in White Adipose Tissue Following Thermal Injury*

  2014cited by this paper
• Occurrence of Multiorgan Dysfunction in Pediatric Burn Patients: Incidence and Clinical Outcome

  2014cited by this paper
• Hypoglycemia Is Associated With Increased Postburn Morbidity and Mortality in Pediatric Patients*

  2014cited by this paper
• Mild Obesity Is Protective After Severe Burn Injury

  2013cited by this paper
• Association of postburn fatty acids and triglycerides with clinical outcome in severely burned children.

  2013cited by this paper
• Severe Injury Is Associated With Insulin Resistance, Endoplasmic Reticulum Stress Response, and Unfolded Protein Response

  2012cited by this paper
• Enteral Nutrition Support in Burn Care: A Review of Current Recommendations as Instituted in the Ross Tilley Burn Centre

  2012cited by this paper
• Hypoglycemia and risk of death in critically ill patients.

  2012cited by this paper
• Long-Term Propranolol Use in Severely Burned Pediatric Patients: A Randomized Controlled Study

  2012cited by this paper
• Burn size and survival probability in paediatric patients in modern burn care: a prospective observational cohort study.

  2012cited by this paper
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  2012cited by this paper
• Propranolol Improves Impaired Hepatic Phosphatidylinositol 3-Kinase/Akt Signaling after Burn Injury

  2012cited by this paper
• Long-Term Persistance of the Pathophysiologic Response to Severe Burn Injury

  2011cited by this paper
• Propranolol decreases cardiac work in a dose-dependent manner in severely burned children.

  2011cited by this paper
• What, how, and how much should patients with burns be fed?

  2011cited by this paper
• Nutrition in burns: Galveston contributions.

  2011cited by this paper
• Insulin Protects against Hepatic Damage Postburn

  2011cited by this paper
• Insulin increases resistance to burn wound infection-associated sepsis

  2010cited by this paper
• Glucose Control in Severely Thermally Injured Pediatric Patients: What Glucose Range Should Be the Target?

  2010cited by this paper
• Intensive insulin therapy in severely burned pediatric patients: a prospective randomized trial.

  2010cited by this paper
• Hypoglycemia and outcome in critically ill patients.

  2010cited by this paper
• Impact of Oxandrolone Treatment on Acute Outcomes After Severe Burn Injury

  2009cited by this paper
• The Hepatic Response to Thermal Injury: Is the Liver Important for Postburn Outcomes?

  2009cited by this paper
• Abnormal insulin sensitivity persists up to three years in pediatric patients post-burn.

  2009cited by this paper
• Pathophysiologic Response to Severe Burn Injury

  2009cited by this paper
• The leading causes of death after burn injury in a single pediatric burn center

  2009cited by this paper
• From endoplasmic-reticulum stress to the inflammatory response

  2008cited by this paper
• Postburn trauma insulin resistance and fat metabolism.

  2008cited by this paper
• Insulin Resistance Postburn: Underlying Mechanisms and Current Therapeutic Strategies

  2008cited by this paper
• Insulin Decreases Inflammatory Signal Transcription Factor Expression in Primary Human Liver Cells after LPS Challenge

  2008cited by this paper
• Gender Differences in Pediatric Burn Patients: Does It Make a Difference?

  2008cited by this paper
• Intensive insulin therapy is associated with reduced infectious complications in burn patients.

  2008cited by this paper
• Impact of Oxandrolone Treatment on Acute Outcomes After Severe Burn Injury

  2008cited by this paper
• Pathophysiologic Response to Severe Burn Injury

  2008cited by this paper
• Trace element requirements in critically ill burned patients.

  2007cited by this paper
• Trace element supplementation after major burns increases burned skin trace element concentrations and modulates local protein metabolism but not whole-body substrate metabolism.

  2007cited by this paper
• Metformin, heart failure, and lactic acidosis: is metformin absolutely contraindicated?

  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• PPAR-α agonism improves whole body and muscle mitochondrial fat oxidation, but does not alter intracellular fat concentrations in burn trauma children in a randomized controlled trial

  2007cited by this paper
• Antioxidant micronutrients in major trauma and burns: evidence and practice.

  2006cited by this paper
• Body composition changes with time in pediatric burn patients.

  2006cited by this paper
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  2006cited by this paper
• Reduction of nosocomial pneumonia after major burns by trace element supplementation: aggregation of two randomised trials

  2006cited by this paper
• Beneficial Effects of Extended Growth Hormone Treatment After Hospital Discharge in Pediatric Burn Patients

  2006cited by this paper
• Effects of Oxandrolone on Outcome Measures in the Severely Burned: A Multicenter Prospective Randomized Double-Blind Trial

  2006cited by this paper
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  2006cited by this paper
• Insulin resistance and improvements in signal transduction

  2006cited by this paper
• The glutamine story: where are we now?

  2006cited by this paper
• Resting energy expenditure in severely burned children: analysis of agreement between indirect calorimetry and prediction equations using the Bland-Altman method.

  2006cited by this paper
• The Influence of Age and Gender on Resting Energy Expenditure in Severely Burned Children

  2006cited by this paper
• Vitamins and trace elements: practical aspects of supplementation.

  2006cited by this paper
• The Atherosclerosis Risk in Communities Study

  2006cited by this paper
• IDENTIFICATION OF FACTORS CONTRIBUTING TO HEPATOMEGALY IN SEVERELY BURNED CHILDREN

  2005cited by this paper
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  2005cited by this paper
• Impact of tight glycemic control in severely burned children.

  2005cited by this paper
• Post burn muscle wasting and the effects of treatments.

  2005cited by this paper
• Can oxidative damage be treated nutritionally?

  2005cited by this paper
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  2005cited by this paper
• Fasting plasma free fatty acids and risk of type 2 diabetes: the atherosclerosis risk in communities study.

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
• Metformin: new understandings, new uses.

  2003cited by this paper
• Influence of fever on the hypermetabolic response in burn-injured children.

  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper

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  2026cites this paper
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  2026cites this paper
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  2020cites this paper
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  2019cites this paper
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