Diallyl disulfide suppresses the growth of human colon tumor cell xenografts in athymic nude mice.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Journal of NutriLife

• Publication date

  1996-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/JN/126.5.1355PMID 8618131
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vivo comparative therapeutic study of optimal administration of 5-fluorouracil and cisplatin using a newly established HST-1 human squamous-carcinoma cell line

  2004cited by this paper
• Diallyl disulfide inhibits the proliferation of human tumor cells in culture.

  1996cited by this paper
• 18:1 n7 fatty acids inhibit growth and decrease inositol phosphate release in HT-29 cells compared to n9 fatty acids.

  1995cited by this paper
• Vegetables, fruit, and colon cancer in the Iowa Women's Health Study.

  1994cited by this paper
• Dietary garlic suppresses DNA adducts caused by N-nitroso compounds.

  1994cited by this paper
• Intraruminal Fluid Administration to Goats: Effects of Handling and Fluid Temperature

  1994cited by this paper
• Potentiation of 5-fluorouracil efficacy by the dihydrouracil dehydrogenase inhibitor, 5-benzyloxybenzyluracil.

  1994cited by this paper
• Comparison of equitoxic radioimmunotherapy and chemotherapy in the treatment of human colonic cancer xenografts.

  1994cited by this paper
• Impact of organosulfur compounds in garlic on canine mammary tumor cells in culture.

  1993cited by this paper
• Effects of Exogenous Lipids on Cancer and Cancer Chemotherapy

  1993cited by this paper
• Impact of various sources of garlic and their constituents on 7,12-dimethylbenz[a]anthracene binding to mammary cell DNA.

  1993cited by this paper
• Mammary cancer prevention by regular garlic and selenium-enriched garlic.

  1992cited by this paper
• Inhibition of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and DNA adducts by garlic powder.

  1992cited by this paper
• In vivo effects of dexamethasone on the tumor growth of glucocorticoid-sensitive Fu5-derived rat hepatoma cells.

  1991cited by this paper
• Garlic: a review of its relationship to malignant disease.

  1990cited by this paper
• Inhibition of soybean lipoxygenase and mouse skin tumor promotion by onion and garlic components.

  1989cited by this paper
• Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide.

  1988cited by this paper
• Inhibitory action of garlic oil on the initiation of benzo[a]pyrene-induced skin carcinogenesis in mice.

  1988cited by this paper
• Superiority of intravesical immunotherapy with Corynebacterium parvum and Allium sativum in control of murine bladder cancer.

  1987cited by this paper
• Diallyl sulfide, a flavor component of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer.

  1987cited by this paper
• Superiority of intralesional immunotherapy with Corynebacterium parvum and Allium sativum in control of murine transitional cell carcinoma.

  1986cited by this paper
• Measurement of protein using bicinchoninic acid.

  1985cited by this paper
• Onion and garlic oils inhibit tumor promotion.

  1983cited by this paper
• Inhibition of the growth of human colon cancer xenografts by polar solvents.

  1982cited by this paper
• Separation of leukocytes from blood and bone marrow. Introduction.

  1968cited by this paper

• Dual Role of Diallyl Disulfide (DADS) on Invasive Potential and β-Catenin Dynamics in HER2-Positive Breast Cancer Cells

  2025cites this paper
• Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment

  2022cites this paper
• In Vitro Toxicity Studies of Bioactive Organosulfur Compounds from Allium spp. with Potential Application in the Agri-Food Industry: A Review

  2022cites this paper
• Chemical constituents and medicinal properties of Allium species

  2021cites this paper
• Anticancer property of allyl sulfides derived from garlic (Allium sativum L.)

  2020cites this paper
• SIÇAN OVARYUM DOKUSUNDA DOKSORUBİSİN İLE İNDÜKLENMİŞ FOLLİKÜLER APOPTOTİK AKTİVASYONDA DİALİL DİSÜLFİT’İN KORUYUCU ETKİSİ

  2020cites this paper
• Diallyl disulfide regulates energy metabolism by targeting AMP-activated protein kinase alpha1 in human gastric cancer cells

  2020cites this paper
• Promotion of unproved and potential dangerous measures in fighting COVID-19 pandemic: urgent need for vigilant appropriate public communication and generation of scientific evidence

  2020cites this paper
• Herbs that heal: Natural panacea for health promotion

  2019cites this paper
• Effects of nutrient and bioactive food components on Alzheimer's disease and epigenetic

  2019cites this paper
• Protective effects of vitamin K2 on 6-OHDA-induced apoptosis in PC12 cells through modulation bax and caspase-3 activation

  2019cites this paper
• Anti-inflammatory drug, leflunomide and its metabolite teriflunomide inhibit NSCLC proliferation in vivo and in vitro.

  2018cites this paper
• Neuro-nutrients as anti-alzheimer's disease agents: A critical review

  2018cites this paper
• Chemopreventive Role of Dietary Phytochemicals in Colorectal Cancer

  2018cites this paper
• Antileishmanial and Immunomodulatory Activity of Allium sativum (Garlic)

  2017cites this paper
• New advances in active packaging incorporated with essential oils or their main components for food preservation

  2017cites this paper
• Identification of potential targets for differentiation in human leukemia cells induced by diallyl disulfide.

  2017cites this paper
• Fighting Cancer with Phytochemicals from Allium Vegetables

  2017cites this paper
• Roles of CYP2e1 in 1,2‐dichloroethane‐induced liver damage in mice

  2016cites this paper
• The Role of Organosulfur Compounds Derived From Allium Vegetables in Cancer Prevention and Therapy

  2016cites this paper
• Title: Diallyl Disulfide (DADS), a constituent of garlic, inactivates NFκB and prevents colitis-induced colorectal cancer by inhibiting GSK-3β Running Title: Diallyl Disulfide (DADS) prevents colorectal cancer in mice

  2016cites this paper
• Diallyl Disul fi de ( DADS ) , a Constituent of Garlic , Inactivates NFk B and Prevents Colitis-Induced Colorectal Cancer by Inhibiting GSK-3 b

  2016cites this paper
• Diallyl Disulfide (DADS), a Constituent of Garlic, Inactivates NF-κB and Prevents Colitis-Induced Colorectal Cancer by Inhibiting GSK-3β

  2016cites this paper
• Garlic Sulfur Compounds Suppress Cancerogenesis and Oxidative Stress: a Review

  2015cites this paper
• Cytotoxic and mutagenic in vitro assessment of two organosulfur compounds derived from onion to be used in the food industry.

  2015influential citation
• Induction of Apoptosis in Human Leukemic Cell Lines by Diallyl Disulfide via Modulation of EGFR/ERK/PKM2 Signaling Pathways.

  2015cites this paper
• Acute toxicological studies of the main organosulfur compound derived from Allium sp. intended to be used in active food packaging.

  2015cites this paper
• Identification of potential targets for diallyl disulfide in human gastric cancer MGC-803 cells using proteomics approaches.

  2015cites this paper
• Antioxidant and Anticoagulant Status Were Improved by Personalized Dietary Intervention Based on Biochemical and Clinical Parameters in Cancer Patients

  2015cites this paper
• 12 – Cancer and the immune system

  2014cites this paper
• An investigation into the anti-cancer mechanism of garlic-related organosulfur compounds

  2014cites this paper
• Garlic: Review of literature.

  2014cites this paper
• Acute modulation of rat plasma glucose byan aqueous garlic extract

  2013cites this paper
• 3 Vitamin K

  2013cites this paper
• Purif ied Protein Fraction of Garlic Extract Modulates Cellular Immune Response against Breast Transplanted Tumors in BALB/c Mice Model

  2013cites this paper
• Vitamin K Antagonist Warfarin for Palliative Treatment of Metachromatic Leukodystrophy, A Compassionate Study of Four Subjects

  2012cites this paper
• A review of volatile sulfur-containing compounds from terrestrial plants: biosynthesis, distribution and analytical methods

  2012cites this paper
• Diallyl disulfide reduced dose-dependently the number of lymphocyte subsets and monocytes in rats.

  2012cites this paper
• Apoptosis Induction of Human Prostate Carcinoma DU145 Cells by Diallyl Disulfide via Modulation of JNK and PI3K/AKT Signaling Pathways

  2012cites this paper
• COMPARISON OF ANTITUMOUR ACTIVITIES OF HEATED AND RAW GARLIC EXTRACTS ON FIBROSARCOMA IN MICE

  2012cites this paper
• Effect of garlic supplementation on complement activity in broiler chickens

  2012cites this paper
• Diallyl Disulfide Increases Histone Acetylation and P21WAF1 Expression in Human Gastric Cancer Cells In vivo and In vitro

  2012cites this paper
• The Attenuation of Early Benzo(a)Pyrene-Induced Carcinogenic Insults by Diallyl Disulfide (DADS) in MCF-10A Cells

  2012cites this paper
• Critical aspects in rationale design of fluorouracil-based adjuvant therapies for the management of colon cancer.

  2012cites this paper
• Anticancer activity of S-allylmercapto-L-cysteine on implanted tumor of human gastric cancer cell.

  2011cites this paper
• Effect of fresh dietary garlic powder on some of the serum biochemical parameters in broiler chicks

  2011cites this paper
• S-allylmercaptocysteine effectively inhibits the proliferation of colorectal cancer cells under in vitro and in vivo conditions.

  2011cites this paper
• H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?

  2011cites this paper
• An Evidence-based Perspective of Allium Sativum (Garlic) for Cancer Patients

  2011cites this paper
• Curcumin-Mediated Cellular Responses in Chemical Carcinogenesis

  2010cites this paper
• Health Promoting Phytochemicals in Vegetables

  2010cites this paper
• A Comprehensive Survey of Garlic Functionality

  2010cites this paper
• Absorption, Storage, and Metabolism of Vitamin K

  2009cites this paper
• Biological properties of garlic and garlic‐derived organosulfur compounds

  2009cites this paper
• Garlic: its anticarcinogenic and antitumorigenic properties.

  2009cites this paper
• PLASMA LIPID MODULATING ACTIVITY OF INTRAPERITONEALLY ADMINISTERED AQUEOUS EXTRACT FROM RAW GARLIC: ACUTE STUDIES IN NORMO-LIPIDEMIC RAT

  2009cites this paper
• The genus Mansoa (Bignoniaceae): a source of organosulfur compounds

  2009cites this paper
• Dietary phytochemicals in prevention and therapy of cancer.

  2008cites this paper
• Multitargeted prevention and therapy of cancer by diallyl trisulfide and related Allium vegetable-derived organosulfur compounds.

  2008cites this paper
• Cell cycle arrest and apoptosis responses of human breast epithelial cells to the synthetic organosulfur compound p-methoxyphenyl p-toluenesulfonate.

  2008cites this paper
• Effects of diallyl disulfide (DADS) on expression of apoptosis associated proteins in androgen independent human prostate cancer cells (PC-3)

  2008cites this paper
• Evaluation of antioxidant capacity of Allium ursinum L. volatile oil and its effect on membrane fluidity

  2008cites this paper
• Apoptosis induced by diallyl disulfide in human breast cancer cell line MCF-7

  2008cites this paper
• In vivo treatment by diallyl disulfide increases histone acetylation in rat colonocytes.

  2007cites this paper
• BIOLOGICAL PROPERTIES OF ONIONS AND GARLIC

  2007cites this paper
• Induction of apoptosis and histone hyperacetylation by diallyl disulfide in prostate cancer cell line PC-3.

  2007cites this paper
• Antiproliferative effects of a series of novel synthetic sulfonate esters on human breast cancer cell line MCF-7.

  2007cites this paper
• Does garlic reduce risk of colorectal cancer? A systematic review.

  2007influential citation
• Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents

  2007cites this paper
• Antiproliferative effect of diallyl disulfide (DADS) on prostate cancer cell line LNCaP

  2006cites this paper
• Significance of Garlic and Its Constituents in Cancer and Cardiovascular Disease

  2006cites this paper
• A novel anticancer effect of garlic derivatives: inhibition of cancer cell invasion through restoration of E-cadherin expression.

  2006cites this paper
• Aged garlic extract has chemopreventative effects on 1,2-dimethylhydrazine-induced colon tumors in rats.

  2006cites this paper
• Erk is involved in the differentiation induced by diallyl disulfide in the human gastric cancer cell line MGC803

  2006cites this paper
• Aged garlic extract has potential suppressive effect on colorectal adenomas in humans.

  2006cites this paper
• Garlic Compound, Diallyl Disulfide Induces Cell Cycle Arrest in Prostate Cancer Cell Line PC-3

  2006cites this paper
• Diallyl disulfide suppresses growth of HL-60 cell through increasing histone acetylation and p21WAF1 expression in vivo and in vitro

  2006cites this paper
• Antioxidative activity and ameliorative effects of memory impairment of sulfur‐containing compounds in Allium species

  2006cites this paper
• Nonnutritive Components in Foods as Modifiers of the Cancer Process

  2005cites this paper
• The anti-invasive activity of cyclooxygenase inhibitors is regulated by the transcription factor ATF3 (activating transcription factor 3)

  2005cites this paper
• Nutraceutical Applications of Garlic and the Intervention of Biotechnology

  2005cites this paper
• Novel Disulfides with Antitumour Efficacy and Specificity

  2005cites this paper
• The effects of allyl sulfides on the induction of phase II detoxification enzymes and liver injury by carbon tetrachloride.

  2004cites this paper
• A cell-based system to identify and characterize the molecular mechanism of drug-metabolizing enzyme (DME) modulators.

  2004cites this paper
• Organosulfur compounds from alliaceae in the prevention of human pathologies.

  2004cites this paper
• Diallyl disulfide (DADS) increases histone acetylation and p21 expression in human colon tumor cell lines

  2004cites this paper
• Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines.

  2004cites this paper
• Post-initiation modulating effects of allyl sulfides in rat hepatocarcinogenesis.

  2004cites this paper
• Diallyl disulfide induces ERK phosphorylation and alters gene expression profiles in human colon tumor cells.

  2003cites this paper
• Diallyl disulfide (DADS) enhances gap-junctional intercellular communication by both direct and indirect mechanisms in rat liver cells.

  2003cites this paper
• Antioxidative activity of sulfur-containing compounds in Allium species for human low-density lipoprotein (LDL) oxidation in vitro.

  2003cites this paper
• Immunomodulatory affect of R10 fraction of garlic extract on natural killer activity.

  2003cites this paper
• Garlic [Allium sativum]: a review of its potential use as an anti-cancer agent.

  2003cites this paper
• Effects of Long-term Vitamin K (Phylloquinone) Intake on Retina Aging

  2003cites this paper
• Nutritional Implications of Sphingolipids: Occurrence and Roles in Cell Regulation

  2003cites this paper
• Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells.

  2002cites this paper
• Immunomodulatory activity of a protein isolated from garlic extract on delayed type hypersensitivity.

  2002cites this paper
• D i s s e r t a t i o n zur Erlangung des Doktorgrades der Fakultät für Chemie und Pharmazie der Ludwig-Maximilians-Universität

  2002cites this paper
• Garlic - A Natural Source of Cancer Preventive Compounds.

  2002influential citation
• Antitumor activity of Z-ajoene, a natural compound purified from garlic: antimitotic and microtubule-interaction properties.

  2002cites this paper