Cinnamon polyphenol extract affects immune responses by regulating anti- and proinflammatory and glucose transporter gene expression in mouse macrophages.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of NutriLife

• Publication date

  2008-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1093/JN/138.5.833PMID 18424588
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Insulin Increases Tristetraprolin and Decreases VEGF Gene Expression in Mouse 3T3–L1 Adipocytes

  2008cited by this paper
• Production and Characterization of ZFP36L1 Antiserum against Recombinant Protein from Escherichia coli

  2008cited by this paper
• Tristetraprolin, a Negative Regulator of mRNA Stability, Is Increased in Old B Cells and Is Involved in the Degradation of E47 mRNA1

  2007cited by this paper
• Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects.

  2007cited by this paper
• Cinnamon extract and polyphenols affect the expression of tristetraprolin, insulin receptor, and glucose transporter 4 in mouse 3T3-L1 adipocytes.

  2007influential reference
• Glucose metabolism in lymphoid and inflammatory cells and tissues

  2007cited by this paper
• Glucose transporter expression on the plasma membrane of resting and activated white blood cells

  2007cited by this paper
• Antibacterial properties and major bioactive components of cinnamon stick (Cinnamomum burmannii): activity against foodborne pathogenic bacteria.

  2007cited by this paper
• Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation.

  2007cited by this paper
• Green tea increases anti-inflammatory tristetraprolin and decreases pro-inflammatory tumor necrosis factor mRNA levels in rats

  2007cited by this paper
• Phosphorylation site analysis of the anti-inflammatory and mRNA-destabilizing protein tristetraprolin

  2007cited by this paper
• Green tea polyphenol extract regulates the expression of genes involved in glucose uptake and insulin signaling in rats fed a high fructose diet.

  2007cited by this paper
• Interferons limit inflammatory responses by induction of tristetraprolin.

  2006cited by this paper
• Whole Cinnamon and Aqueous Extracts Ameliorate Sucrose-Induced Blood Pressure Elevations in Spontaneously Hypertensive Rats

  2006cited by this paper
• Glucocorticoids Regulate Tristetraprolin Synthesis and Posttranscriptionally Regulate Tumor Necrosis Factor Alpha Inflammatory Signaling

  2006cited by this paper
• The U(L)41 protein of herpes simplex virus 1 degrades RNA by endonucleolytic cleavage in absence of other cellular or viral proteins.

  2006cited by this paper
• Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis.

  2006cited by this paper
• Zfp36l3, a Rodent X Chromosome Gene Encoding a Placenta-Specific Member of the Tristetraprolin Family of CCCH Tandem Zinc Finger Proteins

  2005influential reference
• Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum In vivo and In vitro

  2005cited by this paper
• Expression, purification, and biochemical characterization of the antiinflammatory tristetraprolin: a zinc-dependent mRNA binding protein affected by posttranslational modifications.

  2004cited by this paper
• Immunological Characterization of Tristetraprolin as a Low Abundance, Inducible, Stable Cytosolic Protein*

  2004influential reference
• Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity.

  2004cited by this paper
• Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor α, cyclooxygenase 2, and inflammatory arthritis

  2004cited by this paper
• A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells

  2003cited by this paper
• Cinnamon improves glucose and lipids of people with type 2 diabetes.

  2003cited by this paper
• Cinnamon extract (traditional herb) potentiates in vivo insulin-regulated glucose utilization via enhancing insulin signaling in rats.

  2003cited by this paper
• Tristetraprolin Binds to the 3′-Untranslated Region of Cyclooxygenase-2 mRNA

  2003influential reference
• Expression and purification of recombinant tristetraprolin that can bind to tumor necrosis factor-alpha mRNA and serve as a substrate for mitogen-activated protein kinases.

  2003cited by this paper
• Tristetraprolin and other CCCH tandem zinc-finger proteins in the regulation of mRNA turnover.

  2001influential reference
• Gene suppression by tristetraprolin and release by the p38 pathway.

  2001cited by this paper
• HuA and Tristetraprolin Are Induced following T Cell Activation and Display Distinct but Overlapping RNA Binding Specificities*

  2001cited by this paper
• A Hydroxychalcone Derived from Cinnamon Functions as a Mimetic for Insulin in 3T3-L1 Adipocytes

  2001cited by this paper
• Decreased Sensitivity of Tristetraprolin-deficient Cells to p38 Inhibitors Suggests the Involvement of Tristetraprolin in the p38 Signaling Pathway*

  2001cited by this paper
• Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro.

  2000cited by this paper
• Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability.

  2000influential reference
• Opposite Translational Control of GLUT1 and GLUT4 Glucose Transporter mRNAs in Response to Insulin

  1999cited by this paper
• Evidence that Tristetraprolin Binds to AU-Rich Elements and Promotes the Deadenylation and Destabilization of Tumor Necrosis Factor Alpha mRNA

  1999cited by this paper
• Regulation of PTP-1 and Insulin Receptor Kinase by Fractions from Cinnamon: Implications for Cinnamon Regulation of Insulin Signalling

  1998cited by this paper
• Feedback Inhibition of Macrophage Tumor Necrosis Factor-α Production by Tristetraprolin

  1998cited by this paper
• Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.

  1998influential reference
• A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency.

  1996cited by this paper
• Endotoxin-induced enhancement of glucose influx into murine peritoneal macrophages via GLUT1

  1996cited by this paper
• Augmentations of glucose uptake and glucose transporter‐1 in macrophages following thermal injury and sepsis in mice

  1996influential reference
• Endotoxin-Induced Enhancement of Glucose Influx into Murine Peritoneal Macrophages via GLUT1

  1995cited by this paper
• A growth factor-inducible nuclear protein with a novel cysteine/histidine repetitive sequence.

  1990cited by this paper
• Rapid insulin-stimulated accumulation of an mRNA encoding a proline-rich protein.

  1990cited by this paper
• Granulocyte-macrophage colony-stimulating factor and tetradecanoyl phorbol acetate induce a distinct, restricted subset of primary-response TIS genes in both proliferating and terminally differentiated myeloid cells

  1989cited by this paper
• In vivo glucose utilization by individual tissues during nonlethal hypermetabolic sepsis

  1988cited by this paper

• The immunomodulatory role of clove and cinnamon extracts on Klebsiella pneumoniae infected rats

  2025cites this paper
• Therapeutic Potential of Cinnamon in Allergic Disorders: A Narrative Review of Mechanisms of Action and Clinical Applications.

  2025cites this paper
• Polyphenols-mediated immune regulation: Metabolite-driven epigenetic regulatory mechanisms.

  2025cites this paper
• The combined effects of Tabata training and cinnamon supplementation on metabolic changes and body composition in soldiers with overweight or obesity

  2025cites this paper
• Effects of Cinnamon Supplementation on Lipid Profile: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  2024cites this paper
• Lipopolysaccharide regulation of antiinflammatory tristetraprolin family and proinflammatory gene expression in mouse macrophages

  2024cites this paper
• Cinnamon an all-Inclusive Review: Detailed Examination of the Botanical Characteristics, Pharmacological properties, and Therapeutic Potential of Diverse Cinnamon Species

  2024cites this paper
• The Molecular Pharmacology of Phloretin: Anti-Inflammatory Mechanisms of Action

  2023cites this paper
• Bacterial endotoxin lipopolysaccharides regulate gene expression in human colon cancer cells

  2023cites this paper
• Natural products as novel anti-obesity agents: insights into mechanisms of action and potential for therapeutic management

  2023cites this paper
• Analysis of Essential Oils Components from Aromatic Plants Using Headspace Repellent Method against Aedes aegypti Mosquitoes

  2023cites this paper
• Editorial for the Special Issue on Plant Polyphenols in the Immune and Inflammatory Responses

  2023cites this paper
• Plant Polyphenol Gossypol Induced Cell Death and Its Association with Gene Expression in Mouse Macrophages

  2023cites this paper
• Efficacy and safety of dietary polyphenols in rheumatoid arthritis: A systematic review and meta-analysis of 47 randomized controlled trials

  2023cites this paper
• A PROMISING ROLE OF CINNAMON TOWARDS RHEUMATOID ARTHRITIS

  2023cites this paper
• Effect of cinnamon oil supplementation into broiler chicken diets on growth, carcass traits, haemato-biochemical parameters, immune function, antioxidant status and caecal microbial count

  2022cites this paper
• Cottonseed extracts regulate gene expression in human colon cancer cells

  2022cites this paper
• comparative study of the effect of Cinnamomum zeylanicum extract and nanocomplex on some immunological and physiological parameters before and after MTX treatment loading

  2022cites this paper
• Cinnamic Acid Attenuates Peripheral and Hypothalamic Inflammation in High-Fat Diet-Induced Obese Mice

  2022cites this paper
• Identification of Bcl2 as a Stably Expressed qPCR Reference Gene for Human Colon Cancer Cells Treated with Cottonseed-Derived Gossypol and Bioactive Extracts and Bacteria-Derived Lipopolysaccharides

  2022influential citation
• Preparation of a green nanocomposite from Cinnamomum zeylanicum and its effect on some immunological parameters in rats with rheumatoid arthritis

  2022cites this paper
• Role of turmeric and cinnamon spices in digestive, metabolic, and immune systems

  2022cites this paper
• The effects of life style modification versus food supplementation on menopausal symptoms

  2021cites this paper
• Effect of Cinnamon on Inflammatory Factors, Pain and Anthropometric Indices in Progressive-relapsing Multiple Sclerosis Patients: A Randomized Controlled Trial

  2021cites this paper
• Effects of metformin and cinnamon on 1,5 anhydroglucitol, adiponectin and ghrelin on newly diagnosed type 2 diabetes mellitus patients

  2021cites this paper
• Antioxidant Activity of Some Natural Compounds in Alleviating the Hepatotoxicity Effects Induced by Emamectin Benzoate in Male Mice

  2021cites this paper
• Cottonseed-derived gossypol and ethanol extracts differentially regulate cell viability and VEGF gene expression in mouse macrophages

  2021cites this paper
• Effect of Cinnamon on Inflammatory Factors, Pain and Anthropometric Indices in Progressive-relapsing Multiple Sclerosis Patients: A Randomized Controlled Trial

  2021cites this paper
• Nutraceuticals for diabetes and glucose balance

  2021cites this paper
• Tristetraprolin, a Potential Safeguard Against Carcinoma: Role in the Tumor Microenvironment

  2021cites this paper
• Gossypol decreased cell viability and down-regulated the expression of a number of genes in human colon cancer cells

  2021cites this paper
• Apple polyphenols modulates the antioxidant defense response and attenuates inflammatory response concurrent with hepatoprotective effect on grass carp (Ctenopharyngodon idellus) fed low fish meal diet

  2020cites this paper
• Effects of dietary soy isoflavones on growth, antioxidant status, immune response and resistance of juvenile grass carp ( Ctenopharyngodon idella ) to Aeromonas hydrophila challenge

  2020cites this paper
• Pharmacological Properties of Ceylon Cinnamon

  2020cites this paper
• Effects of olive leaf extract ( Olea europaea Leecino ) on growth, haematological parameters, immune system and carcass composition in common carp ( Cyprinus carpio )

  2020cites this paper
• Emerging Therapeutic Effects of Herbal Plants in Rheumatoid Arthritis.

  2020cites this paper
• Bioremediation effect of pomegranate peel on subchronic mercury immunotoxicity on African catfish (Clarias gariepinus)

  2020cites this paper
• Regulation of Cell Viability and Anti-inflammatory Tristetraprolin Family Gene Expression in Mouse Macrophages by Cottonseed Extracts

  2020cites this paper
• Cinnamomum zeylanicum alleviate testicular damage induced by high fat diet in albino rats; histological and ultrastructural studies

  2020cites this paper
• Literature-Based Drug Repurposing in Traditional Chinese Medicine: Reduced Inflammatory M1 Macrophage Polarization by Jisil Haebaek Gyeji-Tang Alleviates Cardiovascular Disease In Vitro and Ex Vivo

  2020cites this paper
• Role of Spices Beyond a Flavouring Agent

  2020cites this paper
• A tale of two cinnamons: A comparative review of the clinical evidence of Cinnamomum verum and C. cassia as diabetes interventions

  2020cites this paper
• Role of intestinal microecology in the regulation of energy metabolism by dietary polyphenols and their metabolites

  2019cites this paper
• EFFICACY AND SAFETY OF STANDARDIZED CINNAMON BARK EXTRACT FOR THE PREVENTION OF CHEMOTHERAPY-INDUCED WEIGHT LOSS AND ALOPECIA IN PATIENTS WITH BREAST CANCER: A RANDOMIZED, DOUBLE-BLIND, AND PLACEBO-CONTROLLED STUDY

  2019cites this paper
• Cinnamon Polyphenol Extract and Insulin Regulate Diacylglycerol Acyltransferase Gene Expression in Mouse Adipocytes and Macrophages

  2019cites this paper
• THE INFLUENCE OF CINNAMON INTAKE ON SOME PRODUCTION PERFORMANCE AND BLOOD PICTURE PARAMETER OF BROILER CHICKENS

  2019cites this paper
• Gossypol but not cottonseed extracts or lipopolysaccharides stimulates HuR gene expression in mouse cells

  2019cites this paper
• Bioactives from culinary spices and herbs: a review

  2019cites this paper
• Pharmacological properties and their medicinal uses of Cinnamomum: a review

  2019cites this paper
• Cinnamon attenuates adiposity and affects the expression of metabolic genes in Diet-Induced obesity model of zebrafish

  2019cites this paper
• Cinnamon Consumption Improves Clinical Symptoms and Inflammatory Markers in Women With Rheumatoid Arthritis

  2018cites this paper
• Regulation of Immune Function by Polyphenols

  2018cites this paper
• Cottonseed Extracts and Gossypol Regulate Diacylglycerol Acyltransferase Gene Expression in Mouse Macrophages

  2018cites this paper
• Isolation of Cottonseed Extracts That Affect Human Cancer Cell Growth

  2018cites this paper
• Identification of the major diacylglycerol acyltransferase mRNA in mouse adipocytes and macrophages

  2018cites this paper
• Evaluation of pharmacodynamic properties and safety of Cinnamomum Zeylanicum (ceylon cinnamon) in health adults: study protocol for a phase I clinical trial

  2017cites this paper
• The chronic effects of dietary (poly)phenols on mitochondrial dysfunction and glucose uptake in cellular models of the liver and skeletal muscle.

  2017cites this paper
• Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance.

  2017cites this paper
• Cinnamon induces browning in subcutaneous adipocytes

  2017cites this paper
• Regulation of the intestinal tight junction by natural polyphenols: A mechanistic perspective

  2017cites this paper
• Additional Therapies and Innovative Technologies

  2017cites this paper
• African Medicinal Spices and Vegetables and Their Potential in the Management of Metabolic Syndrome

  2017cites this paper
• A Clinician's Guide to Integrative Oncology

  2017cites this paper
• Emerging role of HuR in inflammatory response in kidney diseases.

  2017cites this paper
• Novel Roles for the Insulin-Regulated Glucose Transporter-4 in Hippocampally Dependent Memory

  2016cites this paper
• Nutraceuticals in Glucose Balance and Diabetes

  2016cites this paper
• Novel Medical Properties of Cinnamomum zeylanicum Oil against Pseudomonas aeruginosa

  2016cites this paper
• Cinnamon extract exhibits potent anti-proliferative activity by modulating angiogenesis and cyclooxygenase in myeloma cells

  2016cites this paper
• Preparation of Methylated Products of A-type Procyanidin Trimers in Cinnamon Bark and Their Protective Effects on Pancreatic β-Cell.

  2016cites this paper
• Cinnamaldehyde is an effective anti-inflammatory agent for treatment of allergic rhinitis in a rat model.

  2016cites this paper
• Cinnamon and Chronic Diseases.

  2016cites this paper
• PENGARUH MINUMAN DIPERKAYA CINNULIN TERHADAP MDA DAN SENYAWA INFLAMASI PLASMA PENDERITA DMT2

  2016cites this paper
• Biomarkers for diet in cancer prevention studies

  2016cites this paper
• The influence of inflammatory cytokines in physiopathology of suicidal behavior.

  2015cites this paper
• Cinnamon extract lowers glucose, insulin and cholesterol in people with elevated serum glucose

  2015cites this paper
• Functional regulation of Zfp36l1 and Zfp36l2 in response to lipopolysaccharide in mouse RAW264.7 macrophages

  2015cites this paper
• Chapter 17 Herbs and Spices in Cancer Prevention and Treatment

  2015cites this paper
• Cinnamon- A Natural Replacement for Synthetic Drugs: A Review

  2015cites this paper
• Anti-Inflammatory Properties of Botanical Extracts Contribute to Their Protective Effects in Brain Edema in Cerebral Ischemia

  2015cites this paper
• Beneficial effects of Cinnamomum burmannii in the treatment of diabetes mellitus

  2015cites this paper
• 상이한 재료로 제조된 발효식초 유래 다당의 화학적 특성과 면역증진 활성

  2015cites this paper
• Chemical Characteristics and Immuno-Stimulatory Activity of Polysaccharides from Fermented Vinegars Manufactured with Different Raw Materials

  2015cites this paper
• Investigation of the protective effect of Cinnamomum cassia bark extract against H2O2-induced oxidative DNA damage in human peripheral blood lymphocytes and antioxidant activity

  2014cites this paper
• Immunosuppressive Effects of A-Type Procyanidin Oligomers from Cinnamomum tamala

  2014cites this paper
• Modulatory activity of a polyphenolic fraction of Cinnamomum zeylanicum L. bark on multiple arms of immunity in normal and immunocompromised mice

  2014cites this paper
• Identification of a Major Phosphopeptide in Human Tristetraprolin by Phosphopeptide Mapping and Mass Spectrometry

  2014cites this paper
• Efficacy and safety of the topical use of intranasal cinnamon bark extract in seasonal allergic rhinitis patients: A double-blind placebo-controlled pilot study

  2014cites this paper
• Cinnamon polyphenols attenuate the hydrogen peroxide-induced down regulation of S100β secretion by regulating sirtuin 1 in C6 rat glioma cells.

  2014influential citation
• Immunopathological and Antimicrobial Effect of Black Pepper, Ginger and Thyme Extracts on Experimental Model of Acute Hematogenous Pyelonephritis in Albino Rats

  2014cites this paper
• Cinnamon polyphenols regulate S100β, sirtuins, and neuroactive proteins in rat C6 glioma cells.

  2014influential citation
• Anti-inflammatory properties of cinnamon polyphenols and their monomeric precursors

  2014cites this paper
• TYPE 2 DIABETES: INTERACTION BETWEEN CINNAMONPOLYPHENOL AND HUMAN SERUM PROTEIN

  2014cites this paper
• Investigation of Cytotoxic and Genotoxic Potential of Cinnamomum Cassia Bark Water Extract

  2014cites this paper
• Cinnamon Extract Regulates Gene Expression of Lipid and Carbohydrate Metabolism in Streptozotocin Induced Diabetic Wistar Rats

  2013cites this paper
• Molecular mechanisms underpinning laser printer and photocopier induced symptoms, including chronic fatigue syndrome and respiratory tract hyperresponsiveness: pharmacological treatment with cinnamon and hydrogen.

  2013cites this paper
• Essential oils and zirconia dental implant materials.

  2013cites this paper
• Ameliorative Effects of a Polyphenolic Fraction of Cinnamomum zeylanicum L. Bark in Animal Models of Inflammation and Arthritis

  2013cites this paper
• Quantitative PCR for glucose transporter and tristetraprolin family gene expression in cultured mouse adipocytes and macrophages

  2013cites this paper
• Metabolic Syndrome and Inflammation: A Critical Review of In Vitro and Clinical Approaches for Benefit Assessment of Plant Food Supplements

  2013cites this paper
• Influence of Ginger and Cinnamon Intake on Inflammation and Muscle Soreness Endued by Exercise in Iranian Female Athletes

  2013cites this paper