Regulation of Oligodendrocyte Development and CNS Myelination by Growth Factors: Prospects for Therapy of Demyelinating Disease

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Brain Pathology

• Publication date

  1996-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1750-3639.1996.tb00858.xPMID 8864287
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons.

  1995cited by this paper
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• Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein.

  1995cited by this paper
• Insulin-like growth factor I treatment reduces clinical deficits and lesion severity in acute demyelinating experimental autoimmune encephalomyelitis

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  1994cited by this paper
• Transplantation of an oligodendrocyte cell line leading to extensive myelination.

  1994cited by this paper
• Phosphatidylinositol 3‐kinase

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• A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development.

  1994cited by this paper
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  1994cited by this paper
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• The insulin signaling system.

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• Regulation of Oligodendrocyte Development and Central Nervous System Myelination by Insulin‐like Growth Factors a

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• A role for TGF-beta in oligodendrocyte differentiation

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• Multiple extracellular signals are required for long-term oligodendrocyte survival.

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• The oligodendrocyte and its many cellular processes.

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• Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain.

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• Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice.

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• Role of insulin-like growth factors in embryonic and postnatal growth.

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• A singularity of PDGF alpha-receptor expression in the dorsoventral axis of the neural tube may define the origin of the oligodendrocyte lineage.

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• Transient reversion of O4+ Galc− oligodendrocyte progenitor development in response to the phorbol ester TPA

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• The inhibition of oligodendrocytic differentiation of O‐2A progenitors caused by basic fibroblast growth factor is overridden by astrocytes

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• The proliferation of mature oligodendrocytes in vitro is stimulated by basic fibroblast growth factor and inhibited by oligodendrocyte-type 2 astrocyte precursors.

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• Measurement of Insulin-Like Growth Factor-II in Physiological Fluids and Tissues. II. Extraction and Quantification in Rat Tissues*

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• Cytokines in context

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• Cell death during development of the nervous system.

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• Measurement of insulin-like growth factor-II in physiological fluids and tissues. II. Extraction quantification in rat tissues.

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• Glial Cells in the Rat Optic Nerve

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