DNA methylation: dynamic and stable regulation of memory

Abstract Epigenetic mechanisms have emerged as a central process in learning and memory. Histone modifications and DNA methylation are epigenetic events that can mediate gene transcription. Interesting features of these epigenetic changes are their transient and long lasting potential. Recent advances in neuroscience suggest that DNA methylation is both dynamic and stable, mediating the formation and maintenance of memory. In this review, we will further illustrate the recent hypothesis that DNA methylation participates in the transcriptional regulation necessary for memory.

• Publication year

  2011

• Venue

  Biomolecular Concepts

• Publication date

  2011-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1515/BMC.2011.046PMID 25962048PMCID PMC4562211
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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