The Homeobox Gene Caudal Regulates Constitutive Local Expression of Antimicrobial Peptide Genes in Drosophila Epithelia

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Molecular and Cellular Biology

• Publication date

  2004-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.24.1.172-185.2004PMID 14673153PMCID PMC303351
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2002influential reference
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