Transcriptional repression by Msx-1 does not require homeodomain DNA-binding sites

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Molecular and Cellular Biology

• Publication date

  1995-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.15.2.861PMID 7823952PMCID PMC231967
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein.

  1994influential reference
• Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes.

  1994influential reference
• The basics of basal transcription by RNA polymerase II.

  1994cited by this paper
• Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

  1994cited by this paper
• Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

  1994cited by this paper
• Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster

  1994cited by this paper
• Design of a "minimAl" homeodomain: the N-terminal arm modulates DNA binding affinity and stabilizes homeodomain structure.

  1994cited by this paper
• Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain.

  1994influential reference
• A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

  1994influential reference
• Repression of the myelin P0 gene by the POU transcription factor SCIP.

  1993cited by this paper
• Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins

  1993influential reference
• The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

  1993cited by this paper
• Functional domains of the Drosophila Engrailed protein.

  1993influential reference
• Synergistic activation of transcription is mediated by the N-terminal domain of Drosophila fushi tarazu homeoprotein and can occur without DNA binding by the protein

  1993influential reference
• Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB

  1993influential reference
• HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization.

  1993influential reference
• A structure-function analysis of transcriptional repression mediated by the WT1, Wilms' tumor suppressor protein.

  1993cited by this paper
• Functional interaction of the v-Rel and c-Rel oncoproteins with the TATA-binding protein and association with transcription factor IIB

  1993cited by this paper
• Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity.

  1993influential reference
• Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3.

  1993influential reference
• Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain.

  1993cited by this paper
• Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements.

  1993influential reference
• extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1.

  1993influential reference
• A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis.

  1993influential reference
• Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53

  1993cited by this paper
• Initiation of transcription by RNA polymerase II: a multi-step process.

  1993influential reference
• Cell-specific action and mutable structure of a transcription factor effector domain.

  1993cited by this paper
• The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

  1993influential reference
• Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB.

  1993influential reference
• Homeobox genes and axial patterning.

  1992cited by this paper
• Wild-type p53 binds to the TATA-binding protein and represses transcription.

  1992cited by this paper
• Mapping functional specificity in the Dfd and Ubx homeo domains.

  1992influential reference
• Factors involved in specific transcription by mammalian RNA polymerase II: purification and analysis of transcription factor IIA and identification of transcription factor IIJ

  1992influential reference
• Multiple sites of HOX‐7 expression during mouse embryogenesis: Comparison with retinoic acid receptor mRNA localization

  1992cited by this paper
• GAL4 fusion vectors for expression in yeast or mammalian cells.

  1992cited by this paper
• Differential DNA binding properties of three human homeodomain proteins.

  1992influential reference
• Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor

  1992influential reference
• Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription.

  1992influential reference
• Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds.

  1992cited by this paper
• Mammalian homeobox genes in normal development and neoplasia.

  1992influential reference
• Molecular aspects of regeneration in developing vertebrate limbs.

  1992cited by this paper
• Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos

  1992influential reference
• Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation

  1992cited by this paper
• Recognition of the surface of a homeo domain protein.

  1992cited by this paper
• POU-domain transcription factors: pou-er-ful developmental regulators.

  1991cited by this paper
• Structure and functional properties of human general transcription factor IIE

  1991cited by this paper
• Cloning of a human gene encoding the general transcription initiation factor IIB

  1991cited by this paper
• Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation.

  1991cited by this paper
• Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor.

  1991influential reference
• EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

  1991cited by this paper
• The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro.

  1991influential reference
• Altered expression of the chicken homeobox-containing genes GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos.

  1991influential reference
• The Msh-like homeobox genes define domains in the developing vertebrate eye.

  1991cited by this paper
• Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus.

  1991influential reference
• The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

  1991cited by this paper
• Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells.

  1991influential reference
• Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid.

  1991influential reference
• Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains

  1991influential reference
• Oncogenic conversion by regulatory changes in transcription factors.

  1991cited by this paper
• DNA binding specificity of homeodomains.

  1991influential reference
• Cloning and evolutionary analysis of msh-like homeobox genes from mouse, zebrafish and ascidian.

  1991influential reference
• Regulatory crosstalk at composite response elements.

  1991influential reference
• The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds.

  1991cited by this paper
• Activation of class II gene transcription by regulatory factors is potentiated by a novel activity.

  1991cited by this paper
• Family of proteins that interact with TFIID and regulate promoter activity.

  1991cited by this paper
• Mechanism of transcriptional activation by Sp1: evidence for coactivators.

  1990cited by this paper
• Murine developmental control genes.

  1990influential reference
• Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex

  1990influential reference
• Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

  1990cited by this paper
• The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain.

  1990influential reference
• Drosophila Krüppel protein is a transcriptional represser

  1990influential reference
• Factors involved in specific transcription by mammalian RNA polymerase II. Purification and subunit composition of transcription factor IIF.

  1990cited by this paper
• Expression and activity of the POU transcription factor SCIP.

  1990cited by this paper
• Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

  1990influential reference
• Functional dissection of Ultrabithorax proteins in D. melanogaster.

  1990influential reference
• SCIP: a glial POU domain gene regulated by cyclic AMP.

  1989cited by this paper
• Hox‐7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

  1989influential reference
• The structure and function of the homeodomain.

  1989cited by this paper
• A homeodomain substitution changes the regulatory specificity of the deformed protein in Drosophila embryos.

  1989influential reference
• A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

  1989influential reference
• The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

  1989cited by this paper
• Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins.

  1989cited by this paper
• The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator.

  1988influential reference
• GAL4-VP16 is an unusually potent transcriptional activator

  1988influential reference
• Human beta-polymerase gene. Structure of the 5'-flanking region and active promoter.

  1988cited by this paper
• Human β-polymerase gene. Structure of the 5'-flanking region and active promoter

  1988influential reference
• Homeo boxes in the study of development.

  1987influential reference
• Factors involved in specific transcription by mammalian RNA polymerase II. Purification and functional analysis of initiation factors IIB and IIE.

  1987influential reference
• Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

  1985cited by this paper
• Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

  1985influential reference
• Regulation of Cytomegalovirus Gene Expression : a and Promoters Are trans Activated by Viral Functions in Permissive Human Fibroblasts

  year unknowncited by this paper

• Intrahepatic homeobox protein MSX-1 is a novel host restriction factor of hepatitis B virus

  2024cites this paper
• miR-21-5p-loaded bone mesenchymal stem cell-derived exosomes repair ovarian function in autoimmune premature ovarian insufficiency by targeting MSX1.

  2024cites this paper
• Msx genes delineate a novel molecular map of the developing cerebellar neuroepithelium

  2023cites this paper
• Advances in tooth agenesis and tooth regeneration

  2023cites this paper
• Enam expression is regulated by Msx2

  2023cites this paper
• Overexpression of Msx1 in Mouse Lung Leads to Loss of Pulmonary Vessels Following Vascular Hypoxic Injury

  2021cites this paper
• MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells

  2021cites this paper
• Neurogenesis From Neural Crest Cells: Molecular Mechanisms in the Formation of Cranial Nerves and Ganglia

  2020cites this paper
• An Msx2-Sp6-Follistatin Pathway Operates During Late Stages of Tooth Development to Control Amelogenesis

  2020cites this paper
• The development, patterning and evolution of neural crest cell differentiation into cartilage and bone.

  2020cites this paper
• Two novel mutations in MSX1 causing oligodontia

  2020cites this paper
• The role of the Msx1 transcription factor in the intestinal epithelia and colorectal cancer

  2019cites this paper
• Role of magnesium in the expression of MSX-1 and PAX9 molecules during early tooth development

  2018cites this paper
• Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh

  2017cites this paper
• Role of WIP in metastasis and study of transcriptional regulation of N-Wasp

  2016cites this paper
• Novel human mutation and CRISPR/Cas genome-edited mice reveal the importance of C-terminal domain of MSX1 in tooth and palate development

  2016cites this paper
• Craniosynostosis: current conceptions and misconceptions

  2016cites this paper
• Role of MSX1 in Osteogenic Differentiation of Human Dental Pulp Stem Cells

  2016cites this paper
• Transcription Factors in Craniofacial Development: From Receptor Signaling to Transcriptional and Epigenetic Regulation.

  2015cites this paper
• MSX2 in ameloblast cell fate and activity

  2015cites this paper
• THE EFFECT OF EXPRESSION OF ESTRUS AT ARTIFICIAL INSEMINATION ON TARGET GENES IN THE ENDOMETRIUM, CONCEPTUS AND CORPUS LUTEUM OF BEEF COWS

  2015cites this paper
• Repressed BMP signaling reactivates NKL homeobox gene MSX1 in a T-ALL subset

  2015cites this paper
• Msx1 homeodomain transcription factor and TATA-binding protein interact to repress the expression of the glycoprotein hormone α subunit gene.

  2015cites this paper
• Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope development.

  2013cites this paper
• Msx1 regulates proliferation and differentiation of mouse dental mesenchymal cells in culture.

  2013cites this paper
• Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers

  2013cites this paper
• Analysis of the molecular interactions between Msx1 and other key players during mouse limb development

  2013cites this paper
• Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development

  2013cites this paper
• Systems Biology of Early Tooth Development

  2013cites this paper
• MSX1 in relation to clefting. hypodontia and hydrocephaly in humans

  2013cites this paper
• Analysis of the molecular interactions between Msx1 and other key players during mouse limb development

  2013cites this paper
• Genetic Anomalies and Tooth Agenesis: Review Article

  2013cites this paper
• Osr 2 acts downstream of Pax 9 and interacts with both Msx 1 and Pax 9 to pattern the tooth developmental fi

  2011cites this paper
• The yeast two hybrid system in a screen for proteins interacting with axolotl (Ambystoma mexicanum) Msx1 during early limb regeneration.

  2011cites this paper
• Analyse fonctionnelle du gène BMP-2 lors de la régénération du membre chez l’axolotl

  2011cites this paper
• Genetic Studies in the Nigerian Population Implicate an MSX1 Mutation in Complex Oral Facial Clefting Disorders

  2011cites this paper
• Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field.

  2011cites this paper
• HOXB13 is co-localized with androgen receptor to suppress androgen-stimulated prostate-specific antigen expression

  2010cites this paper
• THE ROLE OF LMX1A AND LMX1B IN REGULATING MESENCEPHALON DEVELOPMENT AND DOPAMINE NEURON SPECIFICATION

  2010cites this paper
• In Vitro Osteoblast Differentiation is Negatively Regulated by Hoxc8

  2010cites this paper
• Regulation of Tbx22 during facial and palatal development

  2010influential citation
• YB1/p32, a nuclear Y-box binding protein 1, is a novel regulator of myoblast differentiation that interacts with Msx1 homeoprotein.

  2010cites this paper
• Ludwig Institute for Cancer Research and Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden GENERATION OF DOPAMINE NEURONS IN VIVO AND FROM EMBRYONIC STEM CELLS IN VITRO

  2009cites this paper
• Hydrocephalus SCOping Out the Mechanisms Underlying the Etiology of

  2009cites this paper
• Hypermutability of Hoxa13A and Functional Divergence from Its Paralog are Associated with the Origin of a Novel Developmental Feature in Zebrafish and Related Taxa (Cypriniformes)

  2009cites this paper
• SCO-ping out the mechanisms underlying the etiology of hydrocephalus.

  2009cites this paper
• Analysis of Msx1 and Msx2 transactivation function in the context of the heat shock 70 (Hspa1b) gene promoter.

  2009cites this paper
• Comparison of proliferation and differentiation of calvarial osteoblast cultures derived from Msx2 deficient and wild type mice.

  2009cites this paper
• Regulation of expression of zebrafish (Danio rerio) insulin‐like growth factor 2 receptor: implications for evolution at the IGF2R locus

  2009cites this paper
• Mammalian regeneration and regenerative medicine.

  2008cites this paper
• [Msx1 and its influence on craniofacial growth].

  2007cites this paper
• The role of MSX1 in tooth agenesis in Iranians.

  2007cites this paper
• Molecular genetics of tooth agenesis

  2007cites this paper
• Msx1 et son influence sur la croissance cranio-faciale

  2007cites this paper
• Bone Morphogenetic Protein-Induced Msx1 and Msx2 Inhibit Myocardin-Dependent Smooth Muscle Gene Transcription

  2006cites this paper
• Molecular analysis of placodal development in zebrafish

  2006influential citation
• Bone Morphogenetic Protein-Induced Msx1 and Msx2 Inhibit Myocardin-Dependent Smooth Muscle Gene Transcription (cid:1)

  2006cites this paper
• Morphological change caused by loss of the taxon-specific polyalanine tract in Hoxd-13.

  2006cites this paper
• Identification of intrinsic determinants of midbrain dopamine neurons.

  2006cites this paper
• Molecular Mechanisms of Cytodifferentiation in Mammalian Tooth Development

  2006cites this paper
• Regulation of MT1 Melatonin Receptor Expression in the Foetal Rat Pituitary

  2006cites this paper
• Functional interactions between Dlx2 and lymphoid enhancer factor regulate Msx2

  2006cites this paper
• SMAD 8 binding to mice Msx1 basal promoter is required for transcriptional activation.

  2006cites this paper
• Functional interactions between Dlx 2 and lymphoid enhancer factor regulate Msx 2

  2006cites this paper
• DAF‐12‐dependent rescue of dauer formation in Caenorhabditis elegans by (25S)‐cholestenoic acid

  2006cites this paper
• A novel missense mutation in MSX1 underlies autosomal recessive oligodontia with associated dental anomalies in Pakistani families

  2006cites this paper
• Evolutionarily conserved domains required for activation and repression functions of the Drosophila Hox protein Ultrabithorax

  2005cites this paper
• Expression and regulation of the Msx1 natural antisense transcript during development

  2005cites this paper
• Transcriptional Activity of the Paired-like Homeodomain Proteins CHX10 and VSX1*

  2005cites this paper
• Genetic and epigenetic control of skeletal muscle development.

  2005cites this paper
• Developmental Regulation of Gonadotropin-releasing Hormone Gene Expression by the MSX and DLX Homeodomain Protein Families*

  2005cites this paper
• Repressor domain and nuclear localization signal of the murine Hoxa-11 protein are located in the homeodomain: no evidence for role of poly alanine stretches in transcriptional repression.

  2005cites this paper
• Cellular plasticity in vertebrate regeneration.

  2005cites this paper
• The Groucho-related Gene Family Regulates the Gonadotropin-releasing Hormone Gene through Interaction with the Homeodomain Proteins MSX1 and OCT1*

  2005cites this paper
• Msx1 Cooperates with Histone H1b for Inhibition of Transcription and Myogenesis

  2004cites this paper
• The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E

  2004influential citation
• Patterning Non-neural Ectoderm by Organizer-Modulated Homeodomain Factors

  2004cites this paper
• Molecules Mimicking Smad1 Interacting with Hox Stimulate Bone Formation*

  2004cites this paper
• Distinct activities of Msx1 and Msx3 in dorsal neural tube development

  2004cites this paper
• Identification and characterization of hoxa2 target genes by ChIP

  2004cites this paper
• The mechanism of biogenesis and potential function of the two alternatively spliced mRNAs encoded by the murine Msx3 gene

  2004cites this paper
• Does Vitamin D play a role on Msx1 homeoprotein expression involving an endogenous antisense mRNA?

  2004cites this paper
• The roles of the homeobox genes ALX4 and MSX2 in skull development

  2004cites this paper
• Molecular basis of non-syndromic tooth agenesis: mutations of MSX1 and PAX9 reflect their role in patterning human dentition.

  2003cites this paper
• JUMONJI, a Critical Factor for Cardiac Development, Functions as a Transcriptional Repressor*

  2003cites this paper
• Msx homeobox gene family and craniofacial development

  2003cites this paper
• Msx genes in organogenesis and human disease">Msx genes in organogenesis and human disease

  2003cites this paper
• The Role of MSX1 in Human Tooth Agenesis

  2002cites this paper
• Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle.

  2002cites this paper
• Inducing cellular dedifferentiation: a potential method for enhancing endogenous regeneration in mammals.

  2002cites this paper
• HOX and Non‐HOX Homeobox Genes in Leukemic Hematopoiesis

  2002cites this paper
• Stimulation of Cdx1 by oncogenic β‐catenin/Tcf4 in colon cancer cells; opposite effect of the CDX2 homeoprotein

  2002cites this paper
• Msx3 protein recruits histone deacetylase to down-regulate the Msx1 promoter.

  2001cites this paper
• Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins.

  2001cites this paper
• PRH Represses Transcription in Hematopoietic Cells by at Least Two Independent Mechanisms*

  2001cites this paper
• Identification of Domains Mediating Transcription Activation, Repression, and Inhibition in the Paired-Related Homeobox Protein, Prx2 (S8)

  2001influential citation
• Msx homeobox genes inhibit differentiation through upregulation of cyclin D1.

  2001cites this paper
• The Identification of Prx1 Transcription Regulatory Domains Provides a Mechanism for Unequal Compensation by thePrx1 and Prx2 Loci*

  2001cites this paper
• Evidence that GRIP, a PDZ-domain protein which is expressed in the embryonic forebrain, co-activates transcription with DLX homeodomain proteins.

  2001cites this paper
• Crystal structure of the Msx-1 homeodomain/DNA complex.

  2001cites this paper