Essential Dosage-Dependent Functions of the Transcription Factor Yin Yang 1 in Late Embryonic Development and Cell Cycle Progression

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Molecular and Cellular Biology

• Publication date

  2006-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.26.9.3565-3581.2006PMID 16611997PMCID PMC1447422
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• p53 deficiency exacerbates pleiotropic mitotic defects, changes in nuclearity and polyploidy in transdifferentiating pancreatic acinar cells

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• Yin Yang 1 Cooperates with Activator Protein 2 to Stimulate ERBB2 Gene Expression in Mammary Cancer Cells*

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• Mammalian cells lack checkpoints for tetraploidy, aberrant centrosome number, and cytokinesis failure

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• Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner.

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• Rituximab (chimeric anti-CD20) sensitizes B-NHL cell lines to Fas-induced apoptosis

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• Expression of transcription factor Yin Yang 1 in prostate cancer.

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• Endoplasmic Reticulum Stress Induction of the Grp78/BiP Promoter: Activating Mechanisms Mediated by YY1 and Its Interactive Chromatin Modifiers

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• No rest for REST: REST/NRSF regulation of neurogenesis.

  2005cited by this paper
• REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis.

  2005cited by this paper
• Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes

  2005cited by this paper
• Rituximab-Induced Inhibition of YY1 and Bcl-xL Expression in Ramos Non-Hodgkin’s Lymphoma Cell Line via Inhibition of NF-κB Activity: Role of YY1 and Bcl-xL in Fas Resistance and Chemoresistance, Respectively1

  2005cited by this paper
• Transient requirements of YY1 expression for PcG transcriptional repression and phenotypic rescue

  2005cited by this paper
• Targeted inhibition of the transcription factor YY1 in an embryonal carcinoma cell line results in retarded cell growth, elevated levels of p53 but no increase in apoptotic cell death.

  2005cited by this paper
• Isolation of p53‐target genes and their functional analysis

  2004cited by this paper
• Cell division and cell survival in the absence of survivin.

  2004cited by this paper
• Cell cycle progression after cleavage failure

  2004cited by this paper
• YY1 binding to a subset of p53 DNA-target sites regulates p53-dependent transcription.

  2004cited by this paper
• Hitting their targets: an emerging picture of E2F and cell cycle control.

  2004cited by this paper
• Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis

  2004cited by this paper
• Lamin B1 is required for mouse development and nuclear integrity.

  2004cited by this paper
• Yin Yang 1 is a negative regulator of p53.

  2004influential reference
• Localized domains of G9a-mediated histone methylation are required for silencing of neuronal genes.

  2004cited by this paper
• YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress.

  2004influential reference
• The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.

  2004cited by this paper
• Transcription factor YY1 functions as a PcG protein in vivo

  2003cited by this paper
• Targeted recruitment of a histone H4-specific methyltransferase by the transcription factor YY1.

  2003cited by this paper
• Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation

  2003cited by this paper
• The gene encoding the transcriptional regulator Yin Yang 1 (YY1) is a myeloid transforming gene interfering with neutrophilic differentiation.

  2003cited by this paper
• Yin Yang 1, a vertebrate polycomb group gene, regulates antero-posterior neural patterning.

  2003cited by this paper
• Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression

  2003cited by this paper
• E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints.

  2002cited by this paper
• A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

  2002cited by this paper
• REST Repression of Neuronal Genes Requires Components of the hSWI·SNF Complex*

  2002cited by this paper
• Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function

  2002cited by this paper
• Analyses of p53 Target Genes in the Human Genome by Bioinformatic and Microarray Approaches* 210

  2001cited by this paper
• YY1 as a Regulator of Replication-dependent Hamster Histone H3.2 Promoter and an Interactive Partner of AP-2*

  2001cited by this paper
• Neither p21WAF1 nor 14-3-3sigma prevents G2 progression to mitotic catastrophe in human colon carcinoma cells after DNA damage, but p21WAF1 induces stable G1 arrest in resulting tetraploid cells.

  2001cited by this paper
• DNA microarrays identification of primary and secondary target genes regulated by p53

  2001influential reference
• The Polycomb Group Protein EED Interacts with YY1, and Both Proteins Induce Neural Tissue in XenopusEmbryos

  2001cited by this paper
• Regulation of Transcription Factor YY1 by Acetylation and Deacetylation

  2001cited by this paper
• Regulation of neuronal traits by a novel transcriptional complex.

  2001cited by this paper
• Interaction between YY1 and the Retinoblastoma Protein

  2001cited by this paper
• Mice lacking a CDK inhibitor, p57Kip2, exhibit skeletal abnormalities and growth retardation.

  2000cited by this paper
• Transcriptional Repression by Neuron-Restrictive Silencer Factor Is Mediated via the Sin3-Histone Deacetylase Complex

  2000cited by this paper
• Combinatorial roles of the nuclear receptor corepressor in transcription and development.

  2000cited by this paper
• Widespread recombinase expression using FLPeR (Flipper) mice

  2000cited by this paper
• Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key?

  1999cited by this paper
• Co-stimulation of Promoter for Low Density Lipoprotein Receptor Gene by Sterol Regulatory Element-binding Protein and Sp1 Is Specifically Disrupted by the Yin Yang 1 Protein*

  1999cited by this paper
• Targeted Disruption of Mouse Yin Yang 1 Transcription Factor Results in Peri-Implantation Lethality

  1999cited by this paper
• Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specific target genes.

  1999cited by this paper
• YY1 can inhibit c-Myc function through a mechanism requiring DNA binding of YY1 but neither its transactivation domain nor direct interaction with c-Myc

  1998cited by this paper
• Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor Trident.

  1998cited by this paper
• Autoantibodies to the nuclear phosphoprotein nucleophosmin in breast cancer patients.

  1998cited by this paper
• The Drosophila Polycomb group gene pleiohomeotic encodes a DNA binding protein with homology to the transcription factor YY1.

  1998cited by this paper
• Autoantibodies to the Nucleolar Phosphoprotein Nucleophosmin in Breast Cancer Patients

  1998cited by this paper
• An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

  1998cited by this paper
• Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300.

  1998cited by this paper
• Characterization of the Transcriptional Regulator YY1

  1997cited by this paper
• Everything you have ever wanted to know about Yin Yang 1......

  1997cited by this paper
• Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

  1997cited by this paper
• Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells.

  1996cited by this paper
• Identification of potential target genes for the neuron-restrictive silencer factor.

  1996cited by this paper
• A novel C/EBP beta-YY1 complex controls the cell-type-specific activity of the human papillomavirus type 18 upstream regulatory region

  1996cited by this paper
• Transcriptional repression of the c-fos gene by YY1 is mediated by a direct interaction with ATF/CREB

  1995cited by this paper
• Functional interactions between YY1 and adenovirus E1A.

  1995cited by this paper
• The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes

  1995cited by this paper
• Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300.

  1995cited by this paper
• REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons.

  1995cited by this paper
• Adenovirus E1A243 disrupts the ATF/CREB-YY1 complex at the mouse c-fos promoter

  1995cited by this paper
• Novel embryonic and adult homeotic phenotypes are produced by pleiohomeotic mutations in Drosophila.

  1994cited by this paper
• Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development.

  1994cited by this paper
• Yin-yang 1 activates the c-myc promoter

  1993cited by this paper
• Interaction between transcription factors Spl and YY1

  1993cited by this paper
• Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1.

  1993cited by this paper
• Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc.

  1993cited by this paper
• Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus

  1992cited by this paper
• Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.

  1992cited by this paper
• Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.

  1991cited by this paper
• Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein.

  1991cited by this paper
• Transcriptional repression by YY1, a human GLI-Krüppel-related protein, and relief of repression by adenovirus E1A protein.

  1991cited by this paper
• Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.

  1988cited by this paper
• Maternal expression of genes that regulate the bithorax complex of Drosophila melanogaster.

  1986cited by this paper
• Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays.

  1983cited by this paper

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• YY1 in prostate cancer: multidimensional oncogenicmechanisms and emerging therapeutic vulnerabilities

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• Chromatin factor YY1 controls fetal hematopoietic stem cell migration and engraftment in mice

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• Transcription Factor Yin-Yang 1 governs cardiac metabolic reprogramming in response to exercise or pathological stress.

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• Yin Yang 1: Role in Leishmaniasis

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• Unstructured but critical: The role of YY1 and YY2 disorder in promoter recognition networks, transcriptional control, and oncogenesis.

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• Yin Yang 1: Function, Mechanisms, and Glia

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• YY1 Lactylation Promotes Fibroblast Senescence by Targeting the PU.1-BTG2 Axis to Promote Oral Submucous Fibrosis.

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• Yin yang 1: a potential regulator of immune related diseases and cancer immunity.

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• Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

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• The DDX6/KIFC1 signaling axis, as regulated by YY1, contributes to the malignant behavior of pancreatic cancer

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• KIF18A inactivates hepatic stellate cells and alleviates liver fibrosis through the TTC3/Akt/mTOR pathway

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• YY1 is a transcriptional activator of mouse LINE-1 Tf subfamily

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• YY1 is a transcriptional activator of the mouse LINE-1 Tf subfamily

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• Role of YY1 in the Regulation of Anti-Apoptotic Gene Products in Drug-Resistant Cancer Cells

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• Identification of Candidate Genes for Economically Important Carcass Cutting in Commercial Pigs through GWAS

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• Ying Yang 1 engagement in brain pathology

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• Oligonucleotide correction of an intronic TIMMDC1 variant in cells of patients with severe neurodegenerative disorder

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• Neuronal Yin Yang1 in the prefrontal cortex regulates transcriptional and behavioral responses to chronic stress in mice

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• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated enhancer clusters

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• Transcription factor YY1 contributes to human melanoma cell growth through modulating the p53 signalling pathway

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• Astrocytic Yin Yang 1 is critical for murine brain development and protection against apoptosis, oxidative stress, and inflammation

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• Upregulation of Yin-Yang-1 Associates with Proliferation and Glutamine Metabolism in Esophageal Carcinoma

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• Dual Role of YY1 in HPV Life Cycle and Cervical Cancer Development

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• Obesity-linked circular RNA circTshz2-2 regulates the neuronal cell cycle and spatial memory in the brain

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• YY1 involvement in embryonic development and cancer

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• A histidine cluster determines YY1-compartmentalized coactivators and chromatin elements in phase-separated super-enhancers

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• A lineage-specific requirement for YY1 polycomb group protein function in early T cell development.

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• YY1 Silencing Induces 5-Fluorouracil-Resistance and BCL2L15 Downregulation in Colorectal Cancer Cells: Diagnostic and Prognostic Relevance

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• Effect of the transcription factor YY1 on the development of pancreatic endocrine and exocrine tumors: a narrative review

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• Agent Clustering Strategy Based on Metabolic Flux Distribution and Transcriptome Expression for Novel Drug Development

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• Endothelial specific YY1 deletion restricts tumor angiogenesis and tumor growth

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• Endothelial-specific YY1 governs sprouting angiogenesis through directly interacting with RBPJ

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• YY1lo NKT cells are dedicated IL-10 producers

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• FUT9-Driven Programming of Colon Cancer Cells towards a Stem Cell-Like State

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• Stress-induced epigenetic regulation of transcription in neocortical excitatory neurons drives depression-like behavior

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• Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation.

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• The Two Sides of YY1 in Cancer: A Friend and a Foe

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• Aurora A Phosphorylation of YY1 during Mitosis Inactivates its DNA Binding Activity

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• Model based approaches to characterize heterogeneity in gene regulation across cells and disease types

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• cis‐regulatory control of Mesp1 expression by YY1 and SP1 during mouse embryogenesis

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