Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Nature Cell Biology

• Publication date

  2001-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/35070067PMID 11283612
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Skp1p and the F-Box Protein Rcy1p Form a Non-SCF Complex Involved in Recycling of the SNARE Snc1p in Yeast

  2001cited by this paper
• A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

  2000cited by this paper
• Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes.

  2000cited by this paper
• The F-Box Protein Rcy1p Is Involved in Endocytic Membrane Traffic and Recycling Out of an Early Endosome in Saccharomyces cerevisiae

  2000cited by this paper
• Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha.

  1999cited by this paper
• A generic protein purification method for protein complex characterization and proteome exploration

  1999cited by this paper
• Recruitment of a ROC1–CUL1 Ubiquitin Ligase by Skp1 and HOS to Catalyze the Ubiquitination of IκBα

  1999cited by this paper
• Direct analysis of protein complexes using mass spectrometry

  1999cited by this paper
• Detecting protein function and protein-protein interactions from genome sequences.

  1999cited by this paper
• Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis.

  1999cited by this paper
• ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity.

  1999cited by this paper
• Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.

  1999cited by this paper
• SCF and Cullin/Ring H2-based ubiquitin ligases.

  1999cited by this paper
• Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.

  1999cited by this paper
• Structure and Properties of the Vacuolar (H+)-ATPases*

  1999cited by this paper
• Reversible Association between the V1and V0 Domains of Yeast Vacuolar H+-ATPase Is an Unconventional Glucose-Induced Effect

  1998cited by this paper
• Characterization of a Temperature-sensitive Yeast Vacuolar ATPase Mutant with Defects in Actin Distribution and Bud Morphology*

  1998cited by this paper
• Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis.

  1998cited by this paper
• Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization.

  1998cited by this paper
• Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast.

  1998cited by this paper
• F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.

  1997cited by this paper
• Structure, function and regulation of the vacuolar (H+)-ATPase.

  1997cited by this paper
• Regulating the yeast kinetochore by ubiquitin-dependent degradation and Skp1p-mediated phosphorylation.

  1997cited by this paper
• VMA12 Encodes a Yeast Endoplasmic Reticulum Protein Required for Vacuolar H+-ATPase Assembly*

  1997cited by this paper
• Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

  1997cited by this paper
• A protein linkage map of Escherichia coli bacteriophage T7

  1996cited by this paper
• Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels.

  1996cited by this paper
• Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels.

  1996cited by this paper
• Resolution of Subunit Interactions and Cytoplasmic Subcomplexes of the Yeast Vacuolar Proton-translocating ATPase (*)

  1996cited by this paper
• Release of proteins and peptides from fusion proteins using a recombinant plant virus proteinase.

  1994cited by this paper
• Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast.

  1994cited by this paper
• New heterologous modules for classical or PCR‐based gene disruptions in Saccharomyces cerevisiae

  1994cited by this paper
• The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase.

  1992cited by this paper
• The 31-kDa polypeptide is an essential subunit of the vacuolar ATPase in Saccharomyces cerevisiae.

  1990cited by this paper
• Multiple methods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle

  1987cited by this paper
• Correspondence and requests for materials should be addressed to M.L.L. (email:

  year unknowncited by this paper

• WDR72 Is Required for Urinary Acidification and Normal H+‐ATPase Activity in Intercalated Cells in Mice

  2026cites this paper
• ACLY regulates autolysosome acidification through tubulin acetylation‐mediated assembly of V‐ATPase subunits in Alzheimer's disease model mice

  2025cites this paper
• Effects of the skp1 gene of the SCF complex on lipid metabolism and response to abiotic stress in Chlamydomonas reinhardtii

  2025cites this paper
• Acute high glucose exposure impairs synaptosomal vesicle release activity.

  2025cites this paper
• Ultrasound-triggered lysosomal alkalinization to block autophagy in tumor therapy.

  2025cites this paper
• Interaction of yeast V-ATPase with TLDc protein Rtc5p

  2025cites this paper
• Spatial Regulation of Lysosomal Vesicle Acidification Along the Axon via mRAVE-Dependent v-ATPase Assembly

  2025cites this paper
• Monoclonal nanobodies alter the activity and assembly of the yeast vacuolar H+-ATPase

  2025cites this paper
• Glycoregulation of E3(SCF) ubiquitin ligases in unicellular eukaryotes.

  2025cites this paper
• Anti‐Prion Systems in Saccharomyces cerevisiae

  2025cites this paper
• The ROGDI protein mutated in Kohlschutter–Tonz syndrome is a novel subunit of the Rabconnectin-3 complex implicated in V-ATPase assembly

  2025cites this paper
• Dmxl1 is required for survival in the mouse to organogenesis stages of development

  2025cites this paper
• V‐ATPase Disassembly at the Yeast Lysosome‐Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging

  2025cites this paper
• A heterotrimeric protein complex assembles the metazoan V-ATPase upon dissipation of proton gradients

  2025cites this paper
• Dmxl1 Is an Essential Mammalian Gene that Is Required for V-ATPase Assembly and Function In Vivo

  2024cites this paper
• Structure of yeast RAVE bound to a partial V1 complex

  2024cites this paper
• Molecular mechanism of Oxr1p mediated disassembly of yeast V-ATPase

  2024cites this paper
• Yeast TLDc domain proteins regulate assembly state and subcellular localization of the V-ATPase

  2024cites this paper
• V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is a Phenotypic Driver of Lysosome Dysfunction in Replicative Aging

  2024cites this paper
• Rabconnectin-3α/DMXL2 Is Locally Enriched at the Synaptic Ribbon of Rod Photoreceptor Synapses

  2023cites this paper
• The hybrid RAVE complex plays V-ATPase-dependent and -independent pathobiological roles in Cryptococcus neoformans

  2023cites this paper
• Orphan quality control by an SCF ubiquitin ligase directed to pervasive C-degrons

  2023cites this paper
• Tender love and disassembly: How a TLDc domain protein breaks the V‐ATPase

  2023cites this paper
• The cytosolic N-terminal domain of V-ATPase a-subunits is a regulatory hub targeted by multiple signals

  2023cites this paper
• CryoEM of V-ATPases: Assembly, disassembly, and inhibition.

  2023cites this paper
• A noncanonical function of SKP1 regulates the switch between autophagy and unconventional secretion

  2023cites this paper
• Host-directed therapy for bacterial infections -Modulation of the phagolysosome pathway-

  2023cites this paper
• Identification, Genomic Organization, and Comprehensive Expression Analysis Reveals the Implication of Cicer arietinum SKP1-like Genes in Abiotic Stress

  2022cites this paper
• F-box receptor mediated control of substrate stability and subcellular location organizes cellular development of Aspergillus nidulans

  2022cites this paper
• The Plant V-ATPase

  2022cites this paper
• Anti-Prion Systems Block Prion Transmission, Attenuate Prion Generation, Cure Most Prions as They Arise and Limit Prion-Induced Pathology in Saccharomyces cerevisiae

  2022cites this paper
• Determinants, Maintenance and Function of Organellar pH.

  2022cites this paper
• Chimeric a-subunit isoforms generate functional yeast V-ATPases with altered regulatory properties in vitro and in vivo

  2022cites this paper
• Structural basis of V-ATPase VO region assembly by Vma12p, 21p, and 22p

  2022cites this paper
• Comparative Ubiquitination Proteomics Revealed the Salt Tolerance Mechanism in Sugar Beet Monomeric Additional Line M14

  2022cites this paper
• The Interplay of Key Phospholipid Biosynthetic Enzymes and the Yeast V-ATPase Pump and their Role in Programmed Cell Death

  2021cites this paper
• Defining steps in RAVE-catalyzed V-ATPase assembly using purified RAVE and V-ATPase subcomplexes

  2021cites this paper
• NDST3 deacetylates α‐tubulin and suppresses V‐ATPase assembly and lysosomal acidification

  2021cites this paper
• RAVE and Rabconnectin-3 Complexes as Signal Dependent Regulators of Organelle Acidification

  2021influential citation
• Membrane Proteins | Structure and Mechanism of the Vacuolar H+-ATPase

  2021cites this paper
• Innate immunity to prions: anti-prion systems turn a tsunami of prions into a slow drip

  2021cites this paper
• Coordinated conformational changes in the V1 complex during V-ATPase reversible dissociation

  2021cites this paper
• Reduced SKP1 and CUL1 expression underlies increases in Cyclin E1 and chromosome instability in cellular precursors of high-grade serous ovarian cancer

  2021cites this paper
• How Do Yeast Cells Contend with Prions?

  2020cites this paper
• Interaction between the yeast RAVE complex and Vph1-containing Vo sectors is a central glucose-sensitive interaction required for V-ATPase reassembly

  2020influential citation
• Regulation of synaptic vesicle acidification at the neuronal synapse

  2020cites this paper
• Regulation and function of V-ATPases in physiology and disease.

  2020cites this paper
• ZBED1/DREF: A transcription factor that regulates cell proliferation

  2020cites this paper
• SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1

  2020cites this paper
• Comparative Ubiquitome Analysis under Heat Stress Reveals Diverse Functions of Ubiquitination in Saccharina japonica

  2020cites this paper
• The H+-ATPase (V-ATPase): from proton pump to signaling complex in health and disease

  2020cites this paper
• Protein Homeostasis Networks and the Use of Yeast to Guide Interventions in Alzheimer’s Disease

  2020cites this paper
• Anti-prion systems in yeast

  2019cites this paper
• The vacuolar shapes of ageing: From function to morphology.

  2019cites this paper
• A Humanized Yeast Phenomic Model of Deoxycytidine Kinase to Predict Genetic Buffering of Nucleoside Analog Cytotoxicity

  2019influential citation
• Reciprocal Regulation of V-ATPase and Glycolytic Pathway Elements in Health and Disease

  2019cites this paper
• Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis

  2019cites this paper
• Membrane Protein Complexes: Structure and Function

  2018cites this paper
• FcRav2, a gene with a ROGDI domain involved in Fusarium head blight and crown rot on durum wheat caused by Fusarium culmorum.

  2018cites this paper
• The Vacuolar ATPase - A Nano-scale Motor That Drives Cell Biology.

  2018cites this paper
• Hermes Transposon Mutagenesis Shows [URE3] Prion Pathology Prevented by a Ubiquitin-Targeting Protein: Evidence for Carbon/Nitrogen Assimilation Cross Talk and a Second Function for Ure2p in Saccharomyces cerevisiae

  2018cites this paper
• Arabidopsis SKP1-like protein13 (ASK13) positively regulates seed germination and seedling growth under abiotic stress

  2018cites this paper
• Glucose starvation increases V-ATPase assembly and activity in mammalian cells through AMP kinase and phosphatidylinositide 3-kinase/Akt signaling

  2018cites this paper
• Molecular mechanisms of cutis laxa– and distal renal tubular acidosis–causing mutations in V-ATPase a subunits, ATP6V0A2 and ATP6V0A4

  2018cites this paper
• pH homeostasis links the nutrient sensing PKA/TORC1/Sch9 ménage-à-trois to stress tolerance and longevity

  2018cites this paper
• V-ATPase regulation of Hypoxia Inducible transcription Factors

  2018cites this paper
• The role of sodium hydrogen exchanger isoform 5 (NHE5) in integrin β1 trafficking

  2018cites this paper
• A pH‐sensitive luminal His‐cluster promotes interaction of PAM with V‐ATPase along the secretory and endocytic pathways of peptidergic cells

  2018influential citation
• Characterization of the complex involved in regulating V-ATPase activity of the vacuolar and endosomal membrane

  2017cites this paper
• Breaking up and making up: The secret life of the vacuolar H+‐ATPase

  2017cites this paper
• Regulation of V-ATPase activity.

  2017cites this paper
• Yeast Tok1p channel is a major contributor to membrane potential maintenance under chemical stress.

  2017cites this paper
• Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast

  2017cites this paper
• PURIFICATION OF RAVE COMPLEX FROM Saccharomyces cerevisiae USING FLAG TAG-AFFINITY PURIFICATION METHOD

  2017cites this paper
• Eukaryotic V-ATPase and Its Super-complexes: From Structure and Function to Disease and Drug Targeting

  2016cites this paper
• Vacuolar ATPase in Physiology and Pathology: Roles in Neurobiology, Infectious Disease, and Cancer

  2016cites this paper
• Skp1, a component of E3 ubiquitin ligase, is necessary for growth, sporulation, development and pathogenicity in rice blast fungus (Magnaporthe oryzae).

  2016influential citation
• The Function of V-ATPases in Cancer.

  2016cites this paper
• Vacuolar H+-ATPase Signaling in Cancer

  2016cites this paper
• Skp1, a component of E3 ubiquitin ligase, is necessary for growth, sporulation, development and pathogenicity in rice blast fungus (<fc><i>M</i></fc><i>agnaporthe oryzae</i>)

  2016influential citation
• REGULATION OF NOTCH SIGNALING BY THE ENDO-LYSOSOMAL SYSTEM IN DROSOPHILA: THE ROLE OF ESCRT-0 AND V-ATPASE

  2016cites this paper
• Crystal structure of yeast V1‐ATPase in the autoinhibited state

  2016cites this paper
• Calcium modulation of doxorubicin cytotoxicity in yeast and human cells

  2016cites this paper
• Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells.

  2016cites this paper
• Proton Transport and pH Control in Fungi.

  2016cites this paper
• The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK

  2016cites this paper
• Yeast Saccharomyces cerevisiae adiponectin receptor homolog Izh2 is involved in the regulation of zinc, phospholipid and pH homeostasis.

  2015cites this paper
• Molecular Interactions and Cellular Itinerary of the Yeast RAVE (Regulator of the H+-ATPase of Vacuolar and Endosomal Membranes) Complex*

  2015influential citation
• Intracellular lumen formation in Drosophila proceeds via a novel subcellular compartment

  2015cites this paper
• Proteostasis in the long-lived daf-2 mutant of Caenorhabditis elegans: the influence of protein turnover and stability

  2014cites this paper
• Role of vacuolar ATPase and Skp1 in Sjögren's syndrome.

  2014cites this paper
• Eukaryotic V-ATPase: novel structural findings and functional insights.

  2014cites this paper
• Reassembly Glucose-dependent Vacuolar ATPase andPfk 2 p Is Necessary for pH Homeostasis Yeast Phosphofructokinase-1 Subunit Bioenergetics :

  2014cites this paper
• The RAVE complex is an isoform-specific V-ATPase assembly factor in yeast

  2014influential citation
• Cytosolic pH Regulated by Glucose Promotes V-ATPase Assembly

  2014cites this paper
• Yeast Phosphofructokinase-1 Subunit Pfk2p Is Necessary for pH Homeostasis and Glucose-dependent Vacuolar ATPase Reassembly*

  2014cites this paper
• Vacuolar H+-ATPase Assembly

  2014cites this paper
• Reversible disassembly of the yeast V-ATPase revisited under in vivo conditions.

  2014cites this paper
• Identification of a Novel Mechanism for Regulation of F-box Proteins

  2014cites this paper
• The Function of V-ATPase in the Degradation of Gluconeogenic Enzymes in Yeast Vacuoles

  2014cites this paper