The epigenome: the next substrate for engineering

We are entering an era of epigenome engineering. The precision manipulation of chromatin and epigenetic modifications provides new ways to interrogate their influence on genome and cell function and to harness these changes for applications. We review the design and state of epigenome editing tools, highlighting the unique regulatory properties afforded by these systems.

• Publication year

  2016

• Venue

  Genome Biology

• Publication date

  2016-08-31

• Fields of study

  Biology, Medicine, Engineering

• Identifiers
  DOI 10.1186/s13059-016-1046-5PMID 27582168PMCID 5006378
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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