Host-induced gene silencing of cytochrome P450 lanosterol C14α-demethylase–encoding genes confers strong resistance to Fusarium species

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2013-11-11

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1073/pnas.1306373110PMID 24218613PMCID PMC3845197
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Paralogous cyp51 genes in Fusarium graminearum mediate differential sensitivity to sterol demethylation inhibitors.

  2011influential reference
• The Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) in animal feeding.

  2011cited by this paper
• The many faces of RNAi.

  2011cited by this paper
• The CYP51C gene, a reliable marker to resolve interspecific phylogenetic relationships within the Fusarium species complex and a novel target for species-specific PCR.

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• HIGS: Host-Induced Gene Silencing in the Obligate Biotrophic Fungal Pathogen Blumeria graminis[W][OA]

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• Signatures of Adaptation to Obligate Biotrophy in the Hyaloperonospora arabidopsidis Genome

  2010cited by this paper
• Biochemical principles of small RNA pathways.

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• In vivo trans-specific gene silencing in fungal cells by in planta expression of a double-stranded RNA

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• WITHDRAWN: Gene silencing by double-stranded RNA

  2007cited by this paper
• Gene silencing by double-stranded RNA.

  2007cited by this paper
• Fungicide Resistance In Crop Pathogens How Can It Be Managed

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• Recent progress in the development of RNA interference for plant parasitic nematodes.

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• Determination of the trichothecene mycotoxin chemotypes and associated geographical distribution and phylogenetic species of the Fusarium graminearum clade from China.

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• Epidemiology of Fusarium head blight on small-grain cereals.

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• Overexpression of the 14α-Demethylase Target Gene (CYP51) Mediates Fungicide Resistance in Blumeriella jaapii

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• Posttranscriptional Gene Silencing in Plants

  2006cited by this paper
• The diversity of RNA silencing pathways in plants.

  2006cited by this paper
• Sequence variation in the CYP51 gene of Blumeria graminis associated with resistance to sterol demethylase inhibiting fungicides.

  2005cited by this paper
• Arabidopsis cyp51 Mutant Shows Postembryonic Seedling Lethality Associated with Lack of Membrane Integrity1[w]

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• Effects of trichothecene mycotoxins on eukaryotic cells: A review

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• RNA silencing in plants

  2004cited by this paper
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  2004influential reference
• The Sequence of the Human Genome

  2001cited by this paper
• Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

  2001cited by this paper
• Post-transcriptional gene silencing in plants.

  2001cited by this paper
• Gene silencing by double-stranded RNA.

  2001cited by this paper
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  2000influential reference
• Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance

  1999cited by this paper
• A species of small antisense RNA in posttranscriptional gene silencing in plants.

  1999cited by this paper
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  1998cited by this paper
• Lanosterol 14α-Demethylase (Cytochrome P45014DM)

  1993cited by this paper
• Anti-Candida drugs--the biochemical basis for their activity.

  1987cited by this paper

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