Sld3, which interacts with Cdc45 (Sld4), functions for chromosomal DNA replication in Saccharomyces cerevisiae

No abstract is available for this paper.

• Publication year

  2001

• Venue

  EMBO Journal

• Publication date

  2001-04-17

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/emboj/20.8.2097PMID 11296242PMCID PMC125422
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of the Yeast Cdc7p/Dbf4p Complex Purified from Insect Cells

  2000cited by this paper
• Central role for Cdc45 in establishing an initiation complex of DNA replication in Xenopus egg extracts

  2000cited by this paper
• Initiation of eukaryotic DNA replication: origin unwinding and sequential chromatin association of Cdc45, RPA, and DNA polymerase alpha.

  2000cited by this paper
• Hierarchy of S-Phase-Promoting Factors: Yeast Dbf4-Cdc7 Kinase Requires Prior S-Phase Cyclin-Dependent Kinase Activation

  2000cited by this paper
• Dpb11 Controls the Association between DNA Polymerases α and ɛ and the Autonomously Replicating Sequence Region of Budding Yeast

  2000cited by this paper
• DNA synthesis at individual replication forks requires the essential initiation factor Cdc45p

  2000cited by this paper
• Assembly of a Complex Containing Cdc45p, Replication Protein A, and Mcm2p at Replication Origins Controlled by S-Phase Cyclin-Dependent Kinases and Cdc7p-Dbf4p Kinase

  2000cited by this paper
• The Drosophila mus101 gene, which links DNA repair, replication and condensation of heterochromatin in mitosis, encodes a protein with seven BRCA1 C-terminus domains.

  2000cited by this paper
• Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication.

  1999cited by this paper
• DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.

  1999cited by this paper
• Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin‐ and Dbf4‐dependent kinases

  1998cited by this paper
• The DNA replication fork in eukaryotic cells.

  1998cited by this paper
• Evidence for a Cdc6p‐independent mitotic resetting event involving DNA polymerase α

  1998cited by this paper
• Sld2, Which Interacts with Dpb11 inSaccharomyces cerevisiae, Is Required for Chromosomal DNA Replication

  1998cited by this paper
• Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication

  1998cited by this paper
• Structure of an XRCC1 BRCT domain: a new protein–protein interaction module

  1998cited by this paper
• Cut5 is a component of the UV-responsive DNA damage checkpoint in fission yeast

  1998cited by this paper
• Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin.

  1998cited by this paper
• Xenopus Cdc45‐dependent loading of DNA polymerase α onto chromatin under the control of S‐phase cdk

  1998cited by this paper
• Replication conrol: choreographing replication origins.

  1998cited by this paper
• Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants.

  1997cited by this paper
• Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs.

  1997cited by this paper
• From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

  1997cited by this paper
• Components and dynamics of DNA replication complexes in S. cerevisiae: redistribution of MCM proteins and Cdc45p during S phase.

  1997cited by this paper
• A superfamily of conserved domains in DNA damage‐ responsive cell cycle checkpoint proteins

  1997cited by this paper
• The Genes Encoding the Transcription Factor yTAFII60, the G4p1 Protein and a Putative Glucose Transporter are Contained in a 12·3 kb DNA Fragment on the Left Arm of Saccharomyces cerevisiae Chromosome VII

  1997cited by this paper
• A DNA Helicase Activity Is Associated with an MCM4, -6, and -7 Protein Complex*

  1997cited by this paper
• Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

  1997cited by this paper
• Characterisation of the Schizosaccharomyces pombe rad4/cut5 mutant phenotypes: dissection of DNA replication and G2 checkpoint control function

  1997cited by this paper
• CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication

  1997cited by this paper
• Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis.

  1997cited by this paper
• Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast.

  1997cited by this paper
• Gene identification using the yeast two-hybrid system.

  1997cited by this paper
• Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells.

  1996cited by this paper
• Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast.

  1996cited by this paper
• Cdc45p assembles into a complex with Cdc46p/Mcm5p, is required for minichromosome maintenance, and is essential for chromosomal DNA replication.

  1996cited by this paper
• Cell Cycle Control of DNA Replication

  1996cited by this paper
• Stepwise assembly of initiation complexes at budding yeast replication origins during the cell cycle

  1995cited by this paper
• Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.

  1995cited by this paper
• Analyzing protein-protein interactions using two-hybrid system.

  1995cited by this paper
• Cell cycle control of DNA replication.

  1995cited by this paper
• Replicator dominance in a eukaryotic chromosome.

  1994cited by this paper
• Fission yeast cut5 links nuclear chromatin and M phase regulator in the replication checkpoint control.

  1994cited by this paper
• Fission yeast cut5+, required for S phase onset and M phase restraint, is identical to the radiation-damage repair gene rad4+.

  1993cited by this paper
• ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

  1992cited by this paper
• A rapid method for localized mutagenesis of yeast genes

  1992cited by this paper
• The YDp plasmids: A uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae

  1991cited by this paper
• SV40 DNA replication.

  1988cited by this paper
• The localization of replication origins on ARS plasmids in S. cerevisiae.

  1987cited by this paper
• Eukaryotic DNA replication.

  1986cited by this paper

• Cell cycle-dependent TICRR/TRESLIN and MTBP chromatin binding mechanisms and patterns

  2025cites this paper
• Effects of CDC45 mutations on DNA replication and genome stability.

  2025cites this paper
• Sld3CBD–Cdc45 structural insights into Cdc45 recruitment for CMG complex formation during DNA replication

  2025influential citation
• Due-B Is dispensable for early development and genome duplication in vertebrates

  2025cites this paper
• Unwinding Helicase MCM Functionality for Diagnosis and Therapeutics of Replication Abnormalities Associated with Cancer: A Review

  2024cites this paper
• The effects of CDC45 mutations on DNA replication and genome stability

  2024influential citation
• Assembly, Activation, and Helicase Actions of MCM2-7: Transition from Inactive MCM2-7 Double Hexamers to Active Replication Forks

  2024cites this paper
• Cell Cycle-Dependent TICRR/TRESLIN and MTBP Chromatin Binding Mechanisms and Patterns

  2024cites this paper
• Restricting the level of the proteins essential for the regulation of the initiation step of replication extends the chronological lifespan and reproductive potential in budding yeast

  2024cites this paper
• A proteome-wide yeast degron collection for the dynamic study of protein function

  2024cites this paper
• Disorders in the CMG helicase complex increase the proliferative capacity and delay chronological aging of budding yeast.

  2023cites this paper
• DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in C. elegans

  2023cites this paper
• Dephosphorylation of the pre-initiation complex is critical for origin firing.

  2022cites this paper
• Dimerization of Firing Factors for Replication Origin Activation in Eukaryotes: A Crucial Process for Simultaneous Assembly of Bidirectional Replication Forks?

  2022cites this paper
• The Role of MTBP as a Replication Origin Firing Factor

  2022cites this paper
• Validation of a high throughput screening assay to identify small molecules that target the eukaryotic replicative helicase.

  2022cites this paper
• Multiple roles of Pol epsilon in eukaryotic chromosome replication

  2022cites this paper
• A synonymous variant in a non-canonical exon of CDC45 disrupts splicing in two affected sibs with Meier-Gorlin syndrome with craniosynostosis.

  2021cites this paper
• MTBP phosphorylation controls DNA replication origin firing

  2021cites this paper
• Polo-like kinase 1 (Plk1) regulates DNA replication origin firing and interacts with Rif1 in Xenopus

  2021cites this paper
• Refining the domain architecture model of the replication origin firing factor Treslin/TICRR

  2021cites this paper
• The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure

  2020cites this paper
• DDK regulates replication initiation by controlling the multiplicity of Cdc45-GINS binding to Mcm2-7

  2020cites this paper
• Sen1 Is Recruited to Replication Forks via Ctf4 and Mrc1 and Promotes Genome Stability

  2020cites this paper
• Interaction of replication factor Sld3 and histone acetyl transferase Esa1 alleviates gene silencing and promotes the activation of late and dormant replication origins

  2020cites this paper
• Origin Firing Regulations to Control Genome Replication Timing

  2019cites this paper
• Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

  2019cites this paper
• Control of Eukaryotic DNA Replication Initiation—Mechanisms to Ensure Smooth Transitions

  2019cites this paper
• A stochastic hybrid model of DNA replication incorporating 3D protein mobility dynamics

  2019cites this paper
• Modulating MCM Levels Causes Differential Loading at Origins of Replication and Changes Replication Timing

  2019cites this paper
• The effects of manipulating levels of replication initiation factors on origin firing efficiency in yeast

  2019cites this paper
• Genes to Cells

  2019cites this paper
• DNA topological stress during DNA replication in Saccharomyces cerevisiae

  2019influential citation
• Investigating the role of Rts1 in DNA replication initiation

  2018cites this paper
• Kaposi's Sarcoma-Associated Herpesvirus Deregulates Host Cellular Replication during Lytic Reactivation by Disrupting the MCM Complex through ORF59

  2018cites this paper
• Interaction between DUE-B and Treslin is required to load Cdc45 on chromatin in human cells

  2018cites this paper
• The limiting DNA replication initiation factors Sld2 and Sld3 influence origin efficiency independent of origin firing time

  2018cites this paper
• A Positive Amplification Mechanism Involving a Kinase and Replication Initiation Factor Helps Assemble the Replication Fork Helicase*

  2017cites this paper
• Historical Perspective of Eukaryotic DNA Replication.

  2017cites this paper
• S-phase checkpoint activity and function throughout the cell cycle

  2017cites this paper
• Mechanisms and regulation of DNA replication initiation in eukaryotes

  2017cites this paper
• Dpb11 may function with RPA and DNA to initiate DNA replication

  2017cites this paper
• Firing of Replication Origins Frees Dbf4-Cdc7 to Target Eco1 for Destruction.

  2017cites this paper
• The Intra-S Checkpoint Responses to DNA Damage

  2017cites this paper
• Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

  2017cites this paper
• Diverse roles of Dpb2, the non-catalytic subunit of DNA polymerase ε

  2017cites this paper
• Role of Histone H3 Lysine 56 Acetylation in the Response to Replicative stress

  2017cites this paper
• Pre‐initiation complex assembly functions as a molecular switch that splits the Mcm2‐7 double hexamer

  2017cites this paper
• Single-Molecule Studies of Replication Kinetics in Response to DNA Damage

  2017cites this paper
• New mechanisms involved in the DNA replication stress response of non-transformed human cells

  2016cites this paper
• Role of Posttranslational Modifications in Replication Initiation

  2016cites this paper
• Mecanismos de regulación de la replicación en respuesta a estrés replicativo en Saccharomyces Cerevisiae

  2016cites this paper
• Robust Replication Control Is Generated by Temporal Gaps between Licensing and Firing Phases and Depends on Degradation of Firing Factor Sld2.

  2016cites this paper
• Application of photoactivated localisation microscopy to visualising eukaryotic DNA replication processes

  2016cites this paper
• Elucidating the DDK‐dependent step in replication initiation

  2016cites this paper
• Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

  2016cites this paper
• Introduction to Eukaryotic DNA Replication Initiation

  2016cites this paper
• A Transcriptome-based Perspective of Cell Cycle Regulation in Dinoflagellates.

  2016influential citation
• Assembly of the Cdc45-MCM2-7-GINS Complex, the Replication Helicase

  2016cites this paper
• Molecular Mechanism of DNA Replication

  2016cites this paper
• DNA Replication Timing: Temporal and Spatial Regulation of Eukaryotic DNA Replication

  2016cites this paper
• Sld3-MCM Interaction Facilitated by Dbf4-Dependent Kinase Defines an Essential Step in Eukaryotic DNA Replication Initiation

  2016cites this paper
• Chromosome Duplication in Saccharomyces cerevisiae

  2016cites this paper
• Role of CDK in Replication Initiation

  2016cites this paper
• Structure of human Cdc45 and implications for CMG helicase function

  2016cites this paper
• Roles of Sld2, Sld3, and Dpb11 in Replication Initiation

  2016cites this paper
• Ki67, PCNA, and MCM proteins: Markers of proliferation in the diagnosis of breast cancer.

  2016cites this paper
• Mechanisms Governing DDK Regulation of the Initiation of DNA Replication

  2016cites this paper
• An Mcm10 Mutant Defective in ssDNA Binding Shows Defects in DNA Replication Initiation.

  2016cites this paper
• Interaction of DUE-B and Treslin during the initiation of DNA replication

  2016cites this paper
• Consequences of abnormal CDK activity in S phase

  2016cites this paper
• RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells

  2015cites this paper
• Mcm 2-7-GINS replication fork helicase

  2015cites this paper
• Mcm10 coordinates the timely assembly and activation of the replication fork helicase

  2015cites this paper
• The Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase*

  2015influential citation
• Conserved mechanism for coordinating replication fork helicase assembly with phosphorylation of the helicase

  2015influential citation
• Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin.

  2015cites this paper
• Structural and biochemical basis for the high fidelity and processivity of DNA polymerase ε

  2015cites this paper
• A reconstituted system reveals how activating and inhibitory interactions control DDK dependent assembly of the eukaryotic replicative helicase

  2015cites this paper
• The quaternary structure of the eukaryotic DNA replication proteins Sld7 and Sld3.

  2015cites this paper
• Behavior of replication origins in Eukaryota – spatio-temporal dynamics of licensing and firing

  2015cites this paper
• Dpb11 Protein Helps Control Assembly of the Cdc45·Mcm2-7·GINS Replication Fork Helicase*

  2015cites this paper
• Insights into the Initiation of Eukaryotic DNA Replication

  2015influential citation
• Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation

  2015cites this paper
• Evolutionary conservation of the CDK targets in eukaryotic DNA replication initiation

  2015cites this paper
• Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression

  2015cites this paper
• Switch on the engine: how the eukaryotic replicative helicase MCM2–7 becomes activated

  2015cites this paper
• TERMINATING REPLICATION AT TERS AT EUKARYOTIC CHROMOSOMES

  2014influential citation
• Characterization of Dbf4 structure and function in Saccharomyces cerevisiae DNA replication and checkpoint responses.

  2014cites this paper
• Crystal structure of the homology domain of the eukaryotic DNA replication proteins Sld3/Treslin.

  2014cites this paper
• The Dbf4-Cdc7 Kinase Promotes Mcm2-7 Ring Opening to Allow for Single-stranded DNA Extrusion and Helicase Assembly*

  2014influential citation
• Protein-protein interactions underlying damage checkpointactivation in S. pombe

  2014cites this paper
• The Regulated Loading and Distribution of the Mcm2-7 Helicase During G1

  2014cites this paper
• Origin plasticity during budding yeast DNA replication in vitro

  2014cites this paper
• Different nucleosomal architectures at early and late replicating origins in Saccharomyces cerevisiae

  2014cites this paper
• Helicase activation mechanisms during initiation of DNA replication

  2014cites this paper
• Protein Phosphatase 2A and Cdc7 Kinase Regulate the DNA Unwinding Element-binding Protein in Replication Initiation*

  2014cites this paper
• InteractionRequires Dpb11/TopBP1-GINS Efficient Initiation of DNA Replication in

  2014cites this paper
• Regulation of genome stability via Mcm2-7 ATPase active sites in Saccharomyces cerevisiae

  2014cites this paper
• DNA replication and oncogene-induced replicative stress.

  2014cites this paper