Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Bioessays

• Publication date

  2005-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/bies.20277PMID 16108063
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The BRCA1 RING and BRCT Domains Cooperate in Targeting BRCA1 to Ionizing Radiation-induced Nuclear Foci*

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• Nuclear Targeting and Cell Cycle Regulatory Function of Human BARD1*

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• Interactions between BRCT repeats and phosphoproteins: tangled up in two.

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• BRCA1-Dependent Ubiquitination of γ-Tubulin Regulates Centrosome Number

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• Ubiquitination and Proteasomal Degradation of the BRCA1 Tumor Suppressor Is Regulated during Cell Cycle Progression*

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• Phosphorylated BRCA1 is predominantly located in the nucleus and mitochondria.

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• Cell Cycle Differences in DNA Damage-induced BRCA1 Phosphorylation Affect Its Subcellular Localization*

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• Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

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• BRCA1 gene in breast cancer

  2003influential reference
• MDC1 is required for the intra-S-phase DNA damage checkpoint

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• The BRCT Domain Is a Phospho-Protein Binding Domain

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• Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains*

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• Regulation of tumor suppressors by nuclear-cytoplasmic shuttling.

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• Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.

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• Cancer susceptibility and the functions of BRCA1 and BRCA2.

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• Homologous repair of DNA damage and tumorigenesis:the BRCA connection

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• DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1

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• Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

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• BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

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• 53BP1, a Mediator of the DNA Damage Checkpoint

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• Identification of Residues Required for the Interaction of BARD1 with BRCA1*

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• Impaired DNA Damage Response in Cells Expressing an Exon 11-Deleted Murine Brca1 Variant That Localizes to Nuclear Foci

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• Analysis of Murine Brca2 Reveals Conservation of Protein-Protein Interactions but Differences in Nuclear Localization Signals*

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• Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.

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• Breast cancer genetics: what we know and what we need

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• Identification of a gamma-tubulin-binding domain in BRCA1.

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• DNA double-strand breaks: signaling, repair and the cancer connection

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• Redistribution of BRCA1 among Four Different Protein Complexes following Replication Blockage*

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