The APC subunit Doc1 promotes recognition of the substrate destruction box.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Current Biology

• Publication date

  2005-01-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.CUB.2004.12.066PMID 15649358
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2000influential reference
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• Structures of APC/CCdh1 with substrates identify Cdh1 and Apc10 as the D-box co-receptor

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