Assembly and architecture of HIV.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Advances in Experimental Medicine and Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1007/978-1-4614-0980-9_20PMID 22297526PMCID PMC6743068
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• HIV-1 Budding

  2013cited by this paper
• Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

  2012cited by this paper
• High resolution mass spectrometry.

  2012cited by this paper
• Atomic-level modelling of the HIV capsid

  2011influential reference
• Proton-driven Assembly of the Rous Sarcoma Virus Capsid Protein Results in the Formation of Icosahedral Particles*

  2010cited by this paper
• Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus.

  2010cited by this paper
• HIV-1 Maturation Inhibitor Bevirimat Stabilizes the Immature Gag Lattice

  2010influential reference
• Hydrogen/deuterium exchange analysis of HIV-1 capsid assembly and maturation.

  2010cited by this paper
• Atomic level modeling of the HIV capsid

  2010cited by this paper
• Conserved and Variable Features of Gag Structure and Arrangement in Immature Retrovirus Particles

  2010influential reference
• An RNA structural switch regulates diploid genome packaging by Moloney murine leukemia virus.

  2010cited by this paper
• Definition of a high-affinity Gag recognition structure mediating packaging of a retroviral RNA genome

  2010cited by this paper
• X-ray structures of the hexameric building block of the HIV capsid.

  2009cited by this paper
• Proton-linked dimerization of a retroviral capsid protein initiates capsid assembly.

  2009cited by this paper
• Membrane scission by the ESCRT-III complex

  2009cited by this paper
• Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function.

  2009influential reference
• Dynamics of HIV-1 Assembly and Release

  2009cited by this paper
• Architecture and Secondary Structure of an Entire HIV-1 RNA Genome

  2009cited by this paper
• Imaging the interaction of HIV-1 genomes and Gag during assembly of individual viral particles

  2009cited by this paper
• Structural Basis for ESCRT-III Protein Autoinhibition

  2009cited by this paper
• Visualization of a Missing Link in Retrovirus Capsid Assembly

  2009cited by this paper
• Retroviral capsid assembly: a role for the CA dimer in initiation.

  2009cited by this paper
• Structure of the capsid amino-terminal domain from the betaretrovirus, Jaagsiekte sheep retrovirus.

  2009cited by this paper
• Structure and assembly of immature HIV

  2009influential reference
• HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity*

  2009cited by this paper
• Computational Model of Membrane Fission Catalyzed by ESCRT-III

  2009cited by this paper
• RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis.

  2008influential reference
• Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis.

  2008cited by this paper
• Structural and functional studies of ALIX interactions with YPXnL late domains of HIV-1 and EIAV

  2008cited by this paper
• A molecular switch required for retrovirus assembly participates in the hexagonal immature lattice

  2008cited by this paper
• Critical Role of Conserved Hydrophobic Residues within the Major Homology Region in Mature Retroviral Capsid Assembly

  2008cited by this paper
• Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein*

  2008cited by this paper
• Efficient and Specific Rescue of Human Immunodeficiency Virus Type 1 Budding Defects by a Nedd4-Like Ubiquitin Ligase

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• Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

  2008cited by this paper
• Mutations in the Spacer Peptide and Adjoining Sequences in Rous Sarcoma Virus Gag Lead to Tubular Budding

  2008cited by this paper
• Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation.

  2008cited by this paper
• NEDD4L Overexpression Rescues the Release and Infectivity of Human Immunodeficiency Virus Type 1 Constructs Lacking PTAP and YPXL Late Domains

  2008cited by this paper
• Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores.

  2008cited by this paper
• Solution structure of a double mutant of the carboxy-terminal dimerization domain of the HIV-1 capsid protein.

  2008cited by this paper
• Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24.

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• Helical Structures of ESCRT-III Are Disassembled by VPS4

  2008cited by this paper
• Imaging the biogenesis of individual HIV-1 virions in live cells

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• The structural biology of HIV assembly.

  2008cited by this paper
• Myristoylation Is Required for Human Immunodeficiency Virus Type 1 Gag-Gag Multimerization in Mammalian Cells

  2007cited by this paper
• Flexibility in HIV-1 assembly subunits: solution structure of the monomeric C-terminal domain of the capsid protein.

  2007cited by this paper
• Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

  2007cited by this paper
• Multimerization of the p12 domain is necessary for Mason-Pfizer monkey virus Gag assembly in vitro.

  2007cited by this paper
• Parallels Between Cytokinesis and Retroviral Budding: A Role for the ESCRT Machinery

  2007cited by this paper
• Domain-swapped dimerization of the HIV-1 capsid C-terminal domain

  2007cited by this paper
• Electron cryotomography of immature HIV‐1 virions reveals the structure of the CA and SP1 Gag shells

  2007influential reference
• Conformation of the HIV-1 Gag protein in solution.

  2007cited by this paper
• Electrostatic Interactions Drive Membrane Association of the Human Immunodeficiency Virus Type 1 Gag MA Domain

  2007cited by this paper
• Interactions between HIV-1 Gag molecules in solution: an inositol phosphate-mediated switch.

  2007cited by this paper
• Structure of full-length HIV-1 CA: a model for the mature capsid lattice.

  2007influential reference
• Tail-interacting protein TIP47 is a connector between Gag and Env and is required for Env incorporation into HIV-1 virions

  2006cited by this paper
• The HIV lipidome: a raft with an unusual composition.

  2006cited by this paper
• Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly.

  2006cited by this paper
• Native hepatitis B virions and capsids visualized by electron cryomicroscopy.

  2006cited by this paper
• Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278).

  2006cited by this paper
• The ESCRT complexes: structure and mechanism of a membrane-trafficking network.

  2006cited by this paper
• The matrix protein of human immunodeficiency virus is cleaved and packed into virion cores

  2006cited by this paper
• The mechanism of HIV-1 core assembly: insights from three-dimensional reconstructions of authentic virions.

  2006influential reference
• Composition and sequence-dependent binding of RNA to the nucleocapsid protein of Moloney murine leukemia virus.

  2005cited by this paper
• The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor

  2005cited by this paper
• Three-dimensional structure of HIV-1 virus-like particles by electron cryotomography.

  2005influential reference
• Biochemical Characterization of Rous Sarcoma Virus MA Protein Interaction with Membranes

  2005cited by this paper
• Helical structure determined by NMR of the HIV‐1 (345–392)Gag sequence, surrounding p2: Implications for particle assembly and RNA packaging

  2005cited by this paper
• Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange

  2004cited by this paper
• Entropic switch regulates myristate exposure in the HIV-1 matrix protein.

  2004cited by this paper
• Structural basis for packaging the dimeric genome of Moloney murine leukaemia virus

  2004cited by this paper
• Dimeric rous sarcoma virus capsid protein structure relevant to immature Gag assembly.

  2004cited by this paper
• Assembly Properties of the Human Immunodeficiency Virus Type 1 CA Protein

  2004cited by this paper
• Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane.

  2004cited by this paper
• Flexibility in the P2 domain of the HIV‐1 Gag polyprotein

  2004cited by this paper
• PPPYVEPTAP Motif Is the Late Domain of Human T-Cell Leukemia Virus Type 1 Gag and Mediates Its Functional Interaction with Cellular Proteins Nedd4 and Tsg101

  2004cited by this paper
• High-resolution structure of a retroviral capsid hexameric amino-terminal domain

  2004cited by this paper
• Microbicides urgently needed: statement by IPM CEO, Zeda Rosenberg, on new AIDS statistics. Joint United Nations Programme on HIV/AIDS (UNAIDS) releases the 2004 AIDS epidemic update.

  2004cited by this paper
• Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

  2003cited by this paper
• Structural organization of authentic, mature HIV‐1 virions and cores

  2003cited by this paper
• AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.

  2003cited by this paper
• PPPYEPTAP Motif Is the Late Domain of Human T-Cell Leukemia Virus Type 1 Gag and Mediates Its Functional Interaction with Cellular Proteins Nedd4 and Tsg101

  2003cited by this paper
• PA-457: A potent HIV inhibitor that disrupts core condensation by targeting a late step in Gag processing

  2003cited by this paper
• Charged Assembly Helix Motif in Murine Leukemia Virus Capsid: an Important Region for Virus Assembly and Particle Size Determination

  2003cited by this paper
• Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography

  2003cited by this paper
• Endophilins interact with Moloney murine leukemia virus Gag and modulate virion production

  2003cited by this paper
• Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.

  2003cited by this paper
• The protein network of HIV budding.

  2003cited by this paper
• Partitioning of Lipid-Modified Monomeric GFPs into Membrane Microdomains of Live Cells

  2002cited by this paper
• Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein

  2002cited by this paper
• Characterization of a Putative α-Helix across the Capsid-SP1 Boundary That Is Critical for the Multimerization of Human Immunodeficiency Virus Type 1 Gag

  2002cited by this paper
• Placement of the Structural Proteins in Sindbis Virus

  2002cited by this paper
• Formation of a Human Immunodeficiency Virus Type 1 Core of Optimal Stability Is Crucial for Viral Replication

  2002cited by this paper
• Functional involvement of a novel Nedd4‐like ubiquitin ligase on retrovirus budding

  2002cited by this paper
• Structure of the N-terminal 283-residue fragment of the immature HIV-1 Gag polyprotein

  2002cited by this paper
• The PPPY Motif of Human T-Cell Leukemia Virus Type 1 Gag Protein Is Required Early in the Budding Process

  2002cited by this paper
• Plasma membrane rafts play a critical role in HIV-1 assembly and release

  2001cited by this paper
• Modulation of HIV-like particle assembly in vitro by inositol phosphates

  2001cited by this paper
• Identification of a high affinity nucleocapsid protein binding element within the Moloney murine leukemia virus Psi-RNA packaging signal: implications for genome recognition.

  2001cited by this paper
• Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55Gag

  2001cited by this paper
• HIV-1 and Ebola virus encode small peptide motifs that recruit Tsg101 to sites of particle assembly to facilitate egress

  2001cited by this paper

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• CPSF6 promotes HIV-1 preintegration complex function

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• Profiling HIV1-host protein–protein interaction networks in patient-derived exosome proteins: impact on pathophysiology and innate immune pathways

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• Time-Resolved Fluorescence Imaging and Correlative Cryo-Electron Tomography to Study Structural Changes of the HIV‑1 Capsid

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• Exploring the Structural Divergence of HIV and SRLV Lentiviral Capsids.

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• Kinetic implications of IP6 anion binding on the molecular switch of HIV-1 capsid assembly

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• Distinct Target Site of Lenacapavir in Immature HIV-1 and Concurrent Binding with the Maturation Inhibitor Bevirimat.

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• Quantifying Impact of HIV Receptor Surface Density Reveals Differences in Fusion Dynamics of HIV Strains

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• Kinetic Implications of IP6 Anion Binding on the Molecular Switch of the HIV-1 Capsid Assembly

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• Structural insights into inhibitor mechanisms on immature HIV-1 Gag lattice revealed by high-resolution in situ single-particle cryo-EM

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• The Assembly of HTLV-1—How Does It Differ from HIV-1?

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• Carcinogenic mechanisms of virus-associated lymphoma

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• HIV-1 capsid stability and reverse transcription are finely balanced to minimize sensing of reverse transcription products via the cGAS-STING pathway

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• Cyclophilin A Facilitates HIV-1 DNA Integration

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• A Branched SELEX Approach Identifies RNA Aptamers That Bind Distinct HIV-1 Capsid Structural Components

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• Epigenetic orchestration of the DNA damage response: Insights into the regulatory mechanisms.

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• Help or Hinder: Protein Host Factors That Impact HIV-1 Replication

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• Mcl-1 Protein and Viral Infections: A Narrative Review

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• Differentiation SELEX approach identifies RNA aptamers with different specificities for HIV-1 capsid assembly forms

  2023cites this paper
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• CP-MAS and solution NMR studies of allosteric communication in CA-assemblies of HIV-1.

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• Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication

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• Critical mechanistic features of HIV-1 viral capsid assembly

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• Rotten to the core: antivirals targeting the HIV-1 capsid core

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• Structure of native HIV-1 cores and their interactions with IP6 and CypA

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• HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules

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• HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration

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• Challenging the Existing Model of the Hexameric HIV-1 Gag Lattice and MA Shell Superstructure: Implications for Viral Entry

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• Addressing Antiretroviral Drug Resistance with Host-Targeting Drugs—First Steps towards Developing a Host-Targeting HIV-1 Assembly Inhibitor

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