Novel roles of aquaporins revealed by phenotype analysis of knockout mice

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Reviews of Physiology, Biochemistry and Pharmacology

• Publication date

  2005-08-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/S10254-005-0040-1PMID 16091927
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Aquaporin-4 Gene Disruption in Mice Reduces Brain Swelling and Mortality in Pneumococcal Meningitis*

  2005cited by this paper
• Enhanced macromolecular diffusion in brain extracellular space in mouse models of vasogenic edema measured by cortical surface photobleaching

  2005cited by this paper
• Aquaporin‐4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess

  2005cited by this paper
• Noninvasive early detection of brain edema in mice by near‐infrared light scattering

  2005cited by this paper
• Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin‐1

  2005cited by this paper
• Phenotype analysis of aquaporin-8 null mice.

  2005cited by this paper
• Progressive Adipocyte Hypertrophy in Aquaporin-7-deficient Mice

  2005cited by this paper
• Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption

  2005cited by this paper
• In Vivo Measurement of Brain Extracellular Space Diffusion by Cortical Surface Photobleaching

  2004cited by this paper
• Sevenfold-reduced osmotic water permeability in primary astrocyte cultures from AQP-4-deficient mice, measured by a fluorescence quenching method.

  2004cited by this paper
• Aquaporin-4 gene disruption in mice protects against impaired retinal function and cell death after ischemia.

  2004cited by this paper
• Increased seizure duration in mice lacking aquaporin-4 water channels.

  2004cited by this paper
• Aquaporin Water Channels

  2004cited by this paper
• Increased seizure threshold in mice lacking aquaporin-4 water channels

  2004cited by this paper
• Aquaporin‐4 facilitates reabsorption of excess fluid in vasogenic brain edema

  2004cited by this paper
• Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.

  2004cited by this paper
• Aquaporin-dependent water permeation at the mouse ocular surface: in vivo microfluorimetric measurements in cornea and conjunctiva.

  2004cited by this paper
• Fluid transport across cultured layers of corneal endothelium from aquaporin-1 null mice.

  2004cited by this paper
• Severe alterations of endothelial and glial cells in the blood‐brain barrier of dystrophic mdx mice

  2003cited by this paper
• Delayed K+ clearance associated with aquaporin-4 mislocalization: Phenotypic defects in brains of α-syntrophin-null mice

  2003cited by this paper
• An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain

  2003cited by this paper
• Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice

  2003cited by this paper
• Aquaporin Deletion in Mice Reduces Intraocular Pressure and Aqueous Fluid Production

  2002cited by this paper
• Mildly abnormal retinal function in transgenic mice without Müller cell aquaporin-4 water channels.

  2002cited by this paper
• Impaired Stratum Corneum Hydration in Mice Lacking Epidermal Water Channel Aquaporin-3*

  2002cited by this paper
• Selectively Reduced Glycerol in Skin of Aquaporin-3-deficient Mice May Account for Impaired Skin Hydration, Elasticity, and Barrier Recovery*

  2002cited by this paper
• Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice

  2002cited by this paper
• Structure and function of water channels.

  2002cited by this paper
• Localization of aquaporin‐5 in sweat glands and functional analysis using knockout mice

  2002cited by this paper
• Aquaporin 4 expression in the mammalian inner ear and its role in hearing.

  2002cited by this paper
• [Structure and function of water channels].

  2002cited by this paper
• Evidence against aquaporin‐1‐dependent CO2 permeability in lung and kidney

  2002cited by this paper
• Aquaporin Deletion in Mice Reduces Corneal Water Permeability and Delays Restoration of Transparency after Swelling*

  2002cited by this paper
• Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels.

  2001cited by this paper
• Microvessel overexpression of aquaporin 1 parallels bone marrow angiogenesis in patients with active multiple myeloma

  2001cited by this paper
• Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways.

  2001cited by this paper
• Neonatal Mortality in an Aquaporin-2 Knock-in Mouse Model of Recessive Nephrogenic Diabetes Insipidus*

  2001cited by this paper
• Role of Aquaporin Water Channels in Airway Fluid Transport, Humidification, and Surface Liquid Hydration

  2001cited by this paper
• Erythrocyte Water Permeability and Renal Function in Double Knockout Mice Lacking Aquaporin-1 and Aquaporin-3*

  2001cited by this paper
• Salivary Acinar Cells from Aquaporin 5-deficient Mice Have Decreased Membrane Water Permeability and Altered Cell Volume Regulation*

  2001cited by this paper
• Aquaporin-5 Dependent Fluid Secretion in Airway Submucosal Glands*

  2001cited by this paper
• Aquaporin 5-deficient mouse lungs are hyperresponsive to cholinergic stimulation

  2001cited by this paper
• Noninvasive in vivo fluorescence measurement of airway-surface liquid depth, salt concentration, and pH.

  2001cited by this paper
• Impaired Hearing in Mice Lacking Aquaporin-4 Water Channels*

  2001cited by this paper
• Defective urinary concentrating ability due to a complete deficiency of aquaporin-1.

  2001cited by this paper
• Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

  2000cited by this paper
• Requirement of aquaporin-1 for NaCl-driven water transport across descending vasa recta.

  2000cited by this paper
• Carbon Dioxide Permeability of Aquaporin-1 Measured in Erythrocytes and Lung of Aquaporin-1 Null Mice and in Reconstituted Proteoliposomes*

  2000cited by this paper
• Role of aquaporins in alveolar fluid clearance in neonatal and adult lung, and in oedema formation following acute lung injury: studies in transgenic aquaporin null mice

  2000cited by this paper
• Gastric acid secretion in aquaporin-4 knockout mice.

  2000cited by this paper
• Role of aquaporin water channels in pleural fluid dynamics.

  2000cited by this paper
• Skeletal muscle function and water permeability in aquaporin-4 deficient mice.

  2000cited by this paper
• Lung fluid transport in aquaporin-5 knockout mice.

  2000cited by this paper
• Role of Aquaporin-4 in Airspace-to-Capillary Water Permeability in Intact Mouse Lung Measured by a Novel Gravimetric Method

  2000cited by this paper
• Colon water transport in transgenic mice lacking aquaporin-4 water channels.

  2000cited by this paper
• Tear secretion by lacrimal glands in transgenic mice lacking water channels AQP1, AQP3, AQP4 and AQP5.

  2000cited by this paper
• Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels.

  2000cited by this paper
• Missense mutations in MIP underlie autosomal dominant ‘polymorphic’ and lamellar cataracts linked to 12q

  2000cited by this paper
• Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice.

  2000cited by this paper
• Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice.

  1999cited by this paper
• Reduced osmotic water permeability of the peritoneal barrier in aquaporin-1 knockout mice.

  1999cited by this paper
• Reduced water permeability and altered ultrastructure in thin descending limb of Henle in aquaporin-1 null mice.

  1999cited by this paper
• Lung fluid transport in aquaporin-1 and aquaporin-4 knockout mice.

  1999cited by this paper
• Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas.

  1999cited by this paper
• Defective Secretion of Saliva in Transgenic Mice Lacking Aquaporin-5 Water Channels*

  1999cited by this paper
• Severely Impaired Urinary Concentrating Ability in Transgenic Mice Lacking Aquaporin-1 Water Channels*

  1998cited by this paper
• Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord.

  1998cited by this paper
• Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice.

  1998cited by this paper
• Fourfold reduction of water permeability in inner medullary collecting duct of aquaporin-4 knockout mice.

  1998cited by this paper
• Defective proximal tubular fluid reabsorption in transgenic aquaporin-1 null mice.

  1998cited by this paper
• Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4.

  1997cited by this paper
• Absence of orthogonal arrays in kidney, brain and muscle from transgenic knockout mice lacking water channel aquaporin-4.

  1997cited by this paper
• Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

  1997cited by this paper
• Molecular cloning and expression of a novel human aquaporin from adipose tissue with glycerol permeability.

  1997cited by this paper
• Cell migration: a physically integrated molecular process.

  1996cited by this paper
• The Mercurial Insensitive Water Channel (AQP-4) Forms Orthogonal Arrays in Stably Transfected Chinese Hamster Ovary Cells (*)

  1996cited by this paper
• Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues.

  1995cited by this paper
• Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine.

  1994cited by this paper
• Life at the leading edge: the formation of cell protrusions.

  1993cited by this paper

• Evolutionary Overview of Aquaporin Superfamily.

  2023cites this paper
• Aquaporins in Respiratory System.

  2023cites this paper
• Recent Advances in Tick Antigen Discovery and Anti-Tick Vaccine Development

  2023cites this paper
• The role of mammalian superaquaporins inside the cell: An update.

  2021cites this paper
• Involvement of aquaglyceroporins in energy metabolism in health and disease.

  2021cites this paper
• Aquaporins’ Influence on Different Dental Erosive Wear Phenotypes in Humans

  2020cites this paper
• Differential Expressions of Aquaporin Subtypes in Female Reproductive Tract of Mice

  2020cites this paper
• Aquaporins, evaporative water loss and thermoregulation in heat-acclimated Mongolian gerbils (Meriones unguiculatus).

  2020cites this paper
• Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Stroke among Patients with Hypertension

  2020cites this paper
• AQP5 regulates the proliferation and differentiation of epidermal stem cells in skin aging

  2020cites this paper
• Estradiol Induced Estrogen Receptor-mediated Transcription and Expression of Aquaporin5

  2019cites this paper
• HISTOPHYSIOLOGY OF DUCTAL PANCREATIC SECRETION

  2019cites this paper
• Associations between Aquaglyceroporin Gene Polymorphisms and Risk of Type 2 Diabetes Mellitus

  2018cites this paper
• New insights on Parkinson's disease from differentiation of SH-SY5Y into dopaminergic neurons: An involvement of aquaporin4 and 9

  2018cites this paper
• Loss of Aquaporin-3 in Placenta and Fetal Membranes Induces Growth Restriction in Mice

  2018cites this paper
• Control of infestations by Ixodes ricinus tick larvae in rabbits vaccinated with aquaporin recombinant antigens.

  2017cites this paper
• Aquaporins in boar and bull spermatozoa: identification and functional implications

  2017cites this paper
• Aquaporin-11 (AQP11) Expression in the Mouse Brain

  2016cites this paper
• Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications

  2016cites this paper
• Fragment Screening of Human Aquaporin 1

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• Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications.

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• The effect of AQP3 deficiency on fuel selection during a single bout of exhausting exercise

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• Aquaporins in Salivary Glands: From Basic Research to Clinical Applications

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• The Physiology and Pathophysiology of Pancreatic Ductal Secretion: The Background for Clinicians

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• Electrolyte and Fluid Transporters of Pancreatic Ductal Cells Cystic Fibrosis Transmembrane Conductance Regulator

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• The expression profile of aquaporin 1 in rat myocardium after severe burns.

  2015cites this paper
• Physiological role of aquaporin 5 in salivary glands

  2015cites this paper
• Emerging roles of aquaporins in relation to the physiology of blood-feeding arthropods

  2014cites this paper
• The role of mammalian superaquaporins inside the cell.

  2014cites this paper
• Immunohistochemical distribution and morphometric analysis of aquaporin-3 in oral squamous cell carcinoma.

  2014cites this paper
• miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer

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• Aquaporins in salivary glands and pancreas.

  2014cites this paper
• miR-874 Inhibits cell proliferation, migration and invasion through targeting aquaporin-3 in gastric cancer

  2013cites this paper
• Glial cell changes in epilepsy: overview of the clinical problem and therapeutic opportunities.

  2013cites this paper
• Aquaporins in the adult mouse submandibular and sublingual salivary glands

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• Time-Dependent Expression Patterns of Cardiac Aquaporins Following Myocardial Infarction

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• Regulation of Protein Turnover during Hyper-osmotic Stress in Skeletal Muscle

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• Immunolocalization of water channel aquaporins in human knee articular cartilage with intact and early degenerative regions

  2013cites this paper
• Glycerol Metabolism Alteration in Adipocytes from n3-PUFA-Depleted Rats, an Animal Model for Metabolic Syndrome

  2012cites this paper
• Attenuated Expression and Gelsolin in Association with Induction of Aquaporin-1 and Nitric Oxide Synthase in Dysfunctional Hearts of Aging Mice Exposed to Endotoxin

  2012cites this paper
• Morphofunctional aspects of the blood-brain barrier.

  2012cites this paper
• Effect of acetazolamide on aquaporin-1 and fluid flow in cultured choroid plexus.

  2012cites this paper
• The Cell Biology of Vasopressin Action

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• Docosahexaenoic Acid (DHA) Prevents Binge Ethanol-Dependent Aquaporin-4 Elevations While Inhibiting Neurodegeneration: Experiments in Rat Adult-Age Entorhino-Hippocampal Slice Cultures

  2012cites this paper
• Aquaporins in drug discovery and pharmacotherapy.

  2012cites this paper
• Diuretics: a review

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• Perturbation of glycerol metabolism in hepatocytes from n3-PUFA-depleted rats.

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• Aquaporin-4 Reduces Post-Traumatic Seizure Susceptibility by Promoting Astrocytic Glial Scar Formation in Mice

  2011cites this paper
• Immunolocalization of Aquaporins in Rat Brain

  2011cites this paper
• Role of cAMP‐PKA/CREB pathway in regulation of AQP 5 production in rat nasal epithelium

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• Thirsty business: cell, region, and membrane specificity of aquaporins in the testis, efferent ducts, and epididymis and factors regulating their expression.

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• La capa córnea: mucho más que una barrera inerte. Implicaciones en los tratamientos cosméticos

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• Cardiac Aquaporins: Significance in Health and Disease

  2011influential citation
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• Significance of SGK1 in the regulation of neuronal function

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• Acetazolamide-induced Decrease Of Apical Fluid Flow In Choroid Plexus Is Independent Of The Concomitant Changes In Aquaporin-1 Expression

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• The expression of differentiation markers in aquaporin-3 deficient epidermis

  2009cites this paper
• Aquaporin‐1 activity of plasma membrane affects HT20 colon cancer cell migration

  2009cites this paper
• A role for aquaporin-4 in fluid regulation in the inner retina

  2009cites this paper
• Down-Regulation of Aquaporin-1 in W489 Colon Cancer Cells Inhibits Cell Migration

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• Aquaporin-4 contributes to the resolution of peritumoural brain oedema in human glioblastoma multiforme after combined chemotherapy and radiotherapy.

  2009cites this paper
• Surfing the wave, cycle, life history, and genes/proteins expressed by testicular germ cells. Part 4: Intercellular bridges, mitochondria, nuclear envelope, apoptosis, ubiquitination, membrane/voltage‐gated channels, methylation/acetylation, and transcription factors

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• Automated cell-based assay for screening of aquaporin inhibitors.

  2009cites this paper
• Temporal changes in expression of aquaporin-3, -4, -5 and -8 in rat brains after permanent focal cerebral ischemia.

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• Aquaporins in secretory glands and their role in Sjögren's syndrome.

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• Caractérisation et étude d'un élément régulateur du gène codant pour le récepteur à la vasopressine de type 2

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• Immunohistochemical characterisation of classical scrapie neuropathology in sheep.

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• Acuaporinas: moléculas revelación en cosmética y oncología cutánea

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• WATER CHANNEL ACTIVITY OF PLASMA MEMBRANE AFFECTS CHONDROCYTE MIGRATION AND ADHESION

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• Expression and Localization of Aquaporins in the Kidney of the Musk Shrew (Suncus murinus)

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• Aquaporins and Water Transport in the Cornea

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• A role for aquaporin-4 during induction of form deprivation myopia in chick

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• Invertebrate aquaporins: a review

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• Expression of aquaporin water channels in the rat pituitary gland.

  2007cites this paper
• Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease

  2007cites this paper
• Diabetes insípidas nefrógenas

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• Exceptional overproduction of a functional human membrane protein.

  2007cites this paper
• Caenorhabditis elegans Functional analysis of the aquaporin gene family in

  2007cites this paper
• Greatly impaired migration of implanted aquaporin‐4‐deficient astroglial cells in mouse brain toward a site of injury

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• Expression of aquaporin water channels in rat taste buds.

  2007cites this paper
• A water channel (AQP9) in retinal ganglion cell apoptosis and glaucoma

  2007cites this paper
• Prevention of Skin Tumorigenesis and Impairment of Epidermal Cell Proliferation by Targeted Aquaporin-3 Gene Disruption

  2007cites this paper
• Aquaporins as targets for drug discovery.

  2007cites this paper
• Impaired enterocyte proliferation in aquaporin-3 deficiency in mouse models of colitis

  2007cites this paper
• Functional analysis of the aquaporin gene family in Caenorhabditis elegans.

  2007cites this paper
• Aquaporins in the Central Nervous System

  2007cites this paper
• Hereditary polyuric disorders: new concepts and differential diagnosis.

  2006cites this paper
• Molecular basis and clinical features of nephrogenic diabetes insipidus

  2006cites this paper
• [Nephrogenic diabetes insipidus].

  2006cites this paper
• Nephrogenic diabetes insipidus.

  2006cites this paper
• Aquaporins in the hepatobiliary system

  2006cites this paper
• Function of aquaporins in female and male reproductive systems.

  2006cites this paper
• Immunolocalization of water channel aquaporins in the nasal olfactory mucosa.

  2006cites this paper
• Aquaporins: a promising target for drug development

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• Cardiac aquaporin expression in humans, rats, and mice.

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• Myocardial water handling and the role of aquaporins.

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• Swelling-Activated K+ Efflux and Regulatory Volume Decrease Efficiency in Human Bronchial Epithelial Cells

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