Morphogenetic fields in embryogenesis, regeneration, and cancer: Non-local control of complex patterning

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Biosyst.

• Publication date

  2012-09-01

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1016/j.biosystems.2012.04.005PMID 22542702PMCID PMC3413735
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differentiation without cleavage in the egg of the annelid chaetopterus pergamentaceus

  2018cited by this paper
• Patterns and Problems of Development

  2013influential reference
• The society of cells cancer and control of cell proliferation

  2013cited by this paper
• Endogenous voltage gradients as mediators of cell-cell communication: strategies for investigating bioelectrical signals during pattern formation

  2013cited by this paper
• Cancer: a de-repression of a default survival program common to all cells?: a life-history perspective on the nature of cancer.

  2012cited by this paper
• Modeling Planarian Regeneration: A Primer for Reverse-Engineering the Worm

  2012cited by this paper
• General principles for measuring resting membrane potential and ion concentration using fluorescent bioelectricity reporters.

  2012cited by this paper
• Measuring resting membrane potential using the fluorescent voltage reporters DiBAC4(3) and CC2-DMPE.

  2012cited by this paper
• Molecular bioelectricity in developmental biology: New tools and recent discoveries

  2012cited by this paper
• Normalized shape and location of perturbed craniofacial structures in the Xenopus tadpole reveal an innate ability to achieve correct morphology

  2012cited by this paper
• Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis

  2012influential reference
• Somatic Stem Cells

  2012cited by this paper
• American Journal of Physiology-Cell Physiology theme: ion channels and transporters in cancer.

  2011cited by this paper
• Embryonic morphogenetic field induces phenotypic reversion in cancer cells. Review article.

  2011cited by this paper
• Wholes that cause their parts: organic self-reproduction and the reality of biological teleology.

  2011cited by this paper
• Drosophila as a model of wound healing and tissue regeneration in vertebrates

  2011cited by this paper
• Turing-Child field underlies spatial periodicity in Drosophila and planarians.

  2011cited by this paper
• The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory

  2011cited by this paper
• Book Reviews: Horns, Pronghorns, and Antlers. Evolution, Morphology, Physiology, and Social Significance.

  2011cited by this paper
• A Systems Biology Approach to Cancer: Fractals, Attractors, and Nonlinear Dynamics

  2011cited by this paper
• Electric Field-Guided Neuron Migration:A Novel Approach in Neurogenesis

  2011cited by this paper
• Optogenetic Long-Term Manipulation of Behavior and Animal Development

  2011cited by this paper
• Limb positioning and shear flows in tetrapods

  2011cited by this paper
• The development and application of optogenetics.

  2011cited by this paper
• Ion channels and transporters in cancer. 1. Ion channels and cell proliferation in cancer.

  2011cited by this paper
• The wisdom of the body: future techniques and approaches to morphogenetic fields in regenerative medicine, developmental biology and cancer.

  2011cited by this paper
• Origins of cellular geometry

  2011cited by this paper
• A chemical genetics approach reveals H,K-ATPase-mediated membrane voltage is required for planarian head regeneration.

  2011influential reference
• V‐ATPase‐dependent ectodermal voltage and ph regionalization are required for craniofacial morphogenesis

  2011cited by this paper
• A zebrafish model for nevus regeneration

  2011cited by this paper
• Response to “The tissue organization field theory of cancer: A testable replacement for the somatic mutation theory” DOI: 10.1002/bies.201100025

  2011cited by this paper
• Long-Distance Signals Are Required for Morphogenesis of the Regenerating Xenopus Tadpole Tail, as Shown by Femtosecond-Laser Ablation

  2011cited by this paper
• Generation model of positional values as cell operation during the development of multicellular organisms

  2011cited by this paper
• Planar cell polarity: coordinating morphogenetic cell behaviors with embryonic polarity.

  2011cited by this paper
• The primacy of organic form. (To the memory of Professor Brian Goodwin).

  2010cited by this paper
• Ion channels and the hallmarks of cancer.

  2010cited by this paper
• On growth and form: a Cartesian coordinate system of Wnt and BMP signaling specifies bilaterian body axes

  2010cited by this paper
• Game of Life Cellular Automata

  2010cited by this paper
• Induction of Vertebrate Regeneration by a Transient Sodium Current

  2010cited by this paper
• Biophysics and systems biology

  2010cited by this paper
• Molecular and cellular aspects of amphibian lens regeneration.

  2010cited by this paper
• Bistable dynamics of cardiac cell models coupled by dynamic gap junctions linked to Cardiac Memory

  2010cited by this paper
• Research on early-stage carcinogenesis: are we approaching paradigm instability?

  2010cited by this paper
• Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway

  2010cited by this paper
• Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration.

  2010influential reference
• First order phase transition and hysteresis in a cell's maintenance of the membrane potential - An essential role for the inward potassium rectifiers

  2010cited by this paper
• Cancer attractors: a systems view of tumors from a gene network dynamics and developmental perspective.

  2009influential reference
• Bioelectric controls of cell proliferation: Ion channels, membrane voltage and the cell cycle

  2009cited by this paper
• Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy.

  2009cited by this paper
• Bioelectric mechanisms in regeneration: Unique aspects and future perspectives.

  2009cited by this paper
• Generation of Functional Eyes from Pluripotent Cells

  2009cited by this paper
• Cellular "bauplans": Evolving unicellular forms by means of Julia sets and Pickover biomorphs

  2009cited by this paper
• Regeneration, repair and remembering identity: the three Rs of Hox gene expression.

  2009cited by this paper
• Targeting ion channels in cancer: a novel frontier in antineoplastic therapy.

  2009cited by this paper
• Complexity: A Guided Tour

  2009cited by this paper
• Unified description of regeneration by coupled dynamical systems theory: Intercalary/segmented regeneration in insect legs

  2009cited by this paper
• Bi-stable neural state switches

  2009cited by this paper
• Describing long-range patterns in leaf vasculature by metaphoric fields.

  2009cited by this paper
• Cancer Growth and Its Inhibition in Terms of Coherence

  2009cited by this paper
• Cellular Communication through Light

  2009cited by this paper
• Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats

  2009cited by this paper
• Spike integration and cellular memory in a rhythmic network from Na+/K+ pump current dynamics

  2009cited by this paper
• Modulation of potassium channel function confers a hyperproliferative invasive phenotype on embryonic stem cells

  2008cited by this paper
• Slicing across kingdoms: regeneration in plants and animals.

  2008cited by this paper
• Beyond the Oncogene Paradigm: Understanding Complexity in Cancerogenesis

  2008cited by this paper
• Synthetic morphology: prospects for engineered, self‐constructing anatomies

  2008cited by this paper
• The Turing-Child energy field as a driver of early mammalian development.

  2008cited by this paper
• Can cancer be reversed by engineering the tumor microenvironment?

  2008influential reference
• A “class action” against the microenvironment: do cancer cells cooperate in metastasis?

  2008cited by this paper
• From Signals to Patterns: Space, Time, and Mathematics in Developmental Biology

  2008cited by this paper
• Planar Polarization in Embryonic Epidermis Orchestrates Global Asymmetric Morphogenesis of Hair Follicles

  2008cited by this paper
• Cell polarity and cancer – cell and tissue polarity as a non-canonical tumor suppressor

  2008cited by this paper
• Regulative feedback in pattern formation: towards a general relativistic theory of positional information

  2008cited by this paper
• Mechanically based generative laws of morphogenesis

  2008cited by this paper
• Interpreting voltage-sensitivity of gap junctions as a mechanism of cardiac memory.

  2008cited by this paper
• Live Imaging of Planarian Membrane Potential Using DiBAC4(3).

  2008cited by this paper
• Apoptosis-induced compensatory proliferation. The Cell is dead. Long live the Cell!

  2008cited by this paper
• Melanocytes in development, regeneration, and cancer.

  2008cited by this paper
• Reprogramming multipotent tumor cells with the embryonic neural crest microenvironment

  2008cited by this paper
• Role of Gap Junctions in Embryonic and Somatic Stem Cells

  2008cited by this paper
• Information about a form (on the dynamic laws of morphogenesis)

  2007cited by this paper
• Gap junctional communication in morphogenesis.

  2007cited by this paper
• Prioritising guidance cues: directional migration induced by substratum contours and electrical gradients is controlled by a rho/cdc42 switch.

  2007cited by this paper
• Large-scale biophysics: ion flows and regeneration.

  2007cited by this paper
• Morpheus unbound: reimagining the morphogen gradient.

  2007cited by this paper
• Signaling Pathways in Cancer and Embryonic Stem Cells

  2007cited by this paper
• Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency.

  2007cited by this paper
• Demonstration of the Universality of a New Cellular Automaton

  2007cited by this paper
• EGF receptor signalling is essential for electric-field-directed migration of breast cancer cells

  2007cited by this paper
• Morphogens, morphostats, microarchitecture and malignancy

  2007cited by this paper
• Striving for normality: whole body regeneration through a series of abnormal generations

  2007cited by this paper
• Molecular Basis for the Nerve Dependence of Limb Regeneration in an Adult Vertebrate

  2007cited by this paper
• An innexin-dependent cell network establishes left-right neuronal asymmetry in C. elegans.

  2007influential reference
• H+ pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration

  2007influential reference
• Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor

  2007cited by this paper
• Cell polarity in development and cancer

  2007cited by this paper
• Reprogramming metastatic tumour cells with embryonic microenvironments

  2007cited by this paper
• Reprogramming metastatic melanoma cells to assume a neural crest cell-like phenotype in an embryonic microenvironment.

  2006cited by this paper
• The interpretation of morphogen gradients

  2006cited by this paper
• Activity‐dependent regulation of voltage‐gated Na+ channel expression in Mat‐LyLu rat prostate cancer cell line

  2006cited by this paper

• Mind Everywhere: A Framework for Conceptualizing Goal-Directedness in Biology and Other Domains—Part One

  2026cites this paper
• Remapping and navigation of an embedding space via error minimization: a fundamental organizational principle of cognition in natural and artificial systems

  2026cites this paper
• Living Organs as Micro-Factories: Material-Producing Organoids.

  2026cites this paper
• From Darwin to teleonomy: A categorical final-cause calculus for evolution

  2026cites this paper
• Field-mediated bioelectric basis of morphogenetic prepatterning

  2025cites this paper
• Comparative dentition in free-living bird nest astigmatan mites

  2025cites this paper
• Journal of Mind and Medical Sciences—A Journal of Bidirectional Emergence in Health and Disease

  2025cites this paper
• Building RNA concentration fields

  2025cites this paper
• On generation of Julia sets, Mandelbrot sets and biomorphs via a modification of the viscosity approximation method

  2025cites this paper
• Guiding Cell Migration with Electric Fields: Mechanisms and Applications of Galvanotaxis.

  2025cites this paper
• Topological constraints on self-organisation in locally interacting systems

  2025cites this paper
• The development of code systems during eukaryogenesis and the rise of multicellularity

  2025cites this paper
• Is there a relationship between embryonic bioelectric currents and differentiation waves?

  2025cites this paper
• ZapGPT: Free-form Language Prompting for Simulated Cellular Control.

  2025cites this paper
• Ephaptic-Axonal Interactions Shape Radial Biases During Neural Self-Organization

  2025cites this paper
• Aging as a loss of morphostatic information: a developmental bioelectricity perspective.

  2024cites this paper
• Quantum evolution: terrestrial fine-tuning of magnetic parameters

  2024cites this paper
• Spatiotemporal modeling of molecular holograms.

  2024cites this paper
• On the Mandelbrot set of perturbed cubic complex polynomials

  2024cites this paper
• Four false dichotomies in the study of teleology

  2024cites this paper
• Exploring Biocomplexity in Cancer: A Comprehensive Review

  2024cites this paper
• The salamander blastema within the broader context of metazoan regeneration

  2023cites this paper
• Macroevolution, differentiation trees, and the growth of coding systems

  2023cites this paper
• Unravelling the nexus: Towards a unified model of development, ageing, and cancer

  2023cites this paper
• A pan-cancer analysis indicates long noncoding RNA HAND2-AS1 as a potential prognostic, immunomodulatory and therapeutic biomarker in various cancers including colorectal adenocarcinoma

  2023cites this paper
• A 3D biomimetic optoelectronic scaffold repairs cranial defects

  2023cites this paper
• Goal Directedness and the Field Concept

  2023cites this paper
• Evolutionary trends and goal directedness

  2023cites this paper
• Thinking in 3 dimensions: philosophies of the microenvironment in organoids and organs-on-chip

  2023cites this paper
• Bioelectricity of non-excitable cells and multicellular pattern memories: Biophysical modeling

  2023cites this paper
• Phenotypically Discordant Anomalies in Conjoined Twins: Quirks of Nature Governed by Molecular Pathways?

  2023cites this paper
• Spateo: multidimensional spatiotemporal modeling of single-cell spatial transcriptomics

  2022cites this paper
• The Nervous System as a Regulator of Cancer Hallmarks: Insights into Therapeutic Implications

  2022cites this paper
• Cancer-Specific Resonances

  2022cites this paper
• Vitalism and cognition in a conscious universe

  2022cites this paper
• Cell Responsiveness to Physical Energies: Paving the Way to Decipher a Morphogenetic Code

  2022cites this paper
• Studying Protista WBR and Repair Using Physarum polycephalum.

  2022cites this paper
• Metacognition as a Consequence of Competing Evolutionary Time Scales

  2022cites this paper
• Neurons as hierarchies of quantum reference frames

  2022cites this paper
• Resolving teleology’s false dilemma

  2022cites this paper
• Self-Organization Against Environmental Stressors, Evolved Elaborately Through Spontaneous Turbulent Dilutions, Led Biological Evolution: Chaos/Complexity and Quantum Coherence-Based Novel Theory

  2022influential citation
• Counting with Cilia: The Role of Morphological Computation in Basal Cognition Research

  2022cites this paper
• Somatic Sex: On the Origin of Neoplasms With Chromosome Counts in Uneven Ploidy Ranges

  2021cites this paper
• Self-organization in embryonic development: myth and reality

  2021cites this paper
• Heterochromatin Networks: Topology, Dynamics, and Function (a Working Hypothesis)

  2021cites this paper
• Spatial and temporal waves in vertebrate limb development.

  2021cites this paper
• An externalist teleology

  2021cites this paper
• The UnderstAnding of Enigmas Related to Cancer: Cancer Origin and Progression- A Review

  2021influential citation
• YY1 involvement in embryonic development and cancer

  2021cites this paper
• A single active ring model with velocity self-alignment.

  2021cites this paper
• Understanding Lung Carcinogenesis from a Morphostatic Perspective: Prevention and Therapeutic Potential of Phytochemicals for Targeting Cancer Stem Cells

  2021cites this paper
• Neurotrophic control of size regulation during axolotl limb regeneration

  2021cites this paper
• How the Non-Physical Influences Physics and Physiology: a proposal

  2021cites this paper
• Bioelectrical approaches to cancer as a problem of the scaling of the cellular self.

  2021cites this paper
• The Paradoxical Behavior of microRNA-211 in Melanomas and Other Human Cancers

  2021cites this paper
• Preface.

  2021cites this paper
• When left does not seem right: epigenetic and bioelectric differences between left- and right-sided breast cancer

  2021influential citation
• Morphogenic fields: A coming of age.

  2021cites this paper
• The drawbridge of nature: Evolutionary complexification as a generation and novel interpretation of coding systems

  2021cites this paper
• Morphogenesis as Bayesian inference: A variational approach to pattern formation and control in complex biological systems.

  2020cites this paper
• Scale‐Free Biology: Integrating Evolutionary and Developmental Thinking

  2020cites this paper
• Mitigation of Teratogenic Agents: Is There Promise in Ion Modulating Drugs?

  2020cites this paper
• How Does a Tumor Get Its Shape? MicroRNAs Act as Morphogens at the Cancer Invasion Front

  2020cites this paper
• Ecological Psychology and Enactivism: Perceptually-Guided Action vs. Sensation-Based Enaction1

  2020cites this paper
• How Do Living Systems Create Meaning?

  2020cites this paper
• A Meta-Analysis of Bioelectric Data in Cancer, Embryogenesis, and Regeneration

  2020cites this paper
• "Constraining" the probability toward a specified attractor: Comment on: Morphogenesis as Bayesian inference: A variational approach to pattern formation and control in complex biological systems.

  2020cites this paper
• Electric Fields at Breast Cancer and Cancer Cell Collective Galvanotaxis

  2020cites this paper
• Integrated information as a possible basis for plant consciousness.

  2020cites this paper
• Morphological Coordination: A Common Ancestral Function Unifying Neural and Non-Neural Signaling.

  2020cites this paper
• Revisiting D.W. Smithers’s “Cancer: An Attack on Cytologism” (1962)

  2020cites this paper
• Some Escape Time Results for General Complex Polynomials and Biomorphs Generation by a New Iteration Process

  2020cites this paper
• Revisão de Métodos de Formação de Swarms Utilizando Morfogênese

  2020cites this paper
• Microenvironment in Disease and Aging

  2020influential citation
• A cartography of energy medicine: From subtle anatomy to energy physiology.

  2020cites this paper
• Integrating Evolutionary and Developmental Thinking Into a Scale-free Biology

  2020cites this paper
• The Mechanisms of Embryonic Scaling

  2019cites this paper
• The Symmetry in the Noise-Perturbed Mandelbrot Set

  2019cites this paper
• Magnetic body, bio-harmonies, morphogenesis, and epigenetics

  2019cites this paper
• Life and Death and Consciousness

  2019cites this paper
• Large-scale Interactive Numerical Experiments of Chaos, Solitons and Fractals in Real Time via GPU in a Web Browser.

  2019cites this paper
• The Computational Boundary of a “Self”: Developmental Bioelectricity Drives Multicellularity and Scale-Free Cognition

  2019cites this paper
• CLINICAL ASPECT OF VAYU AS “KARTA GARBHAKRUTINAM” W. S. R TO MORPHOGENETIC FIELD

  2019cites this paper
• Synchronization of Bioelectric Oscillations in Networks of Nonexcitable Cells: From Single-Cell to Multicellular States.

  2019cites this paper
• Scalable sim-to-real transfer of soft robot designs

  2019cites this paper
• A consideration of physiological regulation from the perspective of Bayesian enactivism.

  2019cites this paper
• The Bioelectric Circuitry of the Cell

  2019cites this paper
• The N-Space Episenome Unifies Cellular Information Space-Time within Cognition-Based Evolution.

  2019cites this paper
• A Developmental Perspective on Paragangliar Tumorigenesis

  2019cites this paper
• Fractal Generation in Modified Jungck–S Orbit

  2019cites this paper
• Modeling somatic computation with non-neural bioelectric networks

  2019cites this paper
• Getting philosophical: some comments about the problems of physics, neuroscience, and biology

  2019cites this paper
• Bioelectric Properties of Myogenic Progenitor Cells

  2019influential citation
• Regeneration in distantly related species: common strategies and pathways

  2018cites this paper
• Physical constraints in cell fate specification. A case in point: Microgravity and phenotypes differentiation.

  2018cites this paper
• Getting Philosophical: On the Problems in Physics, Neuroscience & Biology

  2018cites this paper
• Gravity Constraints Drive Biological Systems Toward Specific Organization Patterns

  2018cites this paper
• The ontogenetic saga of a social brain

  2018cites this paper
• Morphogenesis in TGD Universe

  2018cites this paper
• Characterizing Inner Pressure and Stiffness of Trophoblast and Inner Cell Mass of Blastocysts.

  2018cites this paper