Cyclosporine and the immune response: basic aspects.

No abstract is available for this paper.

• Publication year

  1986

• Venue

  Critical Reviews in Immunology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 2942335
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Biological effects of cyclosporin A: A new antilymphocytic agent

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• Activity of cyclosporin A in experimental influenza virus infection in mice

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  1985cited by this paper
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  1985cited by this paper
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  1985cited by this paper
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• Differential effect of cyclosporin A on the expression of T and B lymphocyte activation antigens.

  1984cited by this paper
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  1984cited by this paper
• Cyclosporine: a new immunosuppressive agent for organ transplantation.

  1984cited by this paper
• Induction of interleukin 2 messenger RNA inhibited by cyclosporin A.

  1984cited by this paper
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  1984cited by this paper
• THE EFFECT OF CYCLOSPORINE ON ORNITHINE DECARBOXYLASE INDUCTION WITH MITOGENS, ANTIGENS, AND LYMPHOKINES

  1984cited by this paper
• Quantitative fluorescence analysis of cyclosporine binding to human leukocytes.

  1984cited by this paper
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  1984cited by this paper
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  1984cited by this paper
• Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen.

  1984cited by this paper
• Stimulation of lymphokine release from T lymphoblasts. Requirement for mRNA synthesis and inhibition by cyclosporin A

  1984cited by this paper
• Phorbol ester increases the level of interleukin 2 mRNA in mitogen-stimulated human lymphocytes.

  1984cited by this paper
• Cyclophilin: a specific cytosolic binding protein for cyclosporin A.

  1984cited by this paper
• Correction: Uptake and Nature of the Intracellular Binding of Cyclosporin A in a Murine Thymoma Cell Line, BW5147

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• Antigen presentation: comments on its regulation and mechanism.

  1984cited by this paper
• CYCLOSPORINE DOES NOT PREVENT CYTOPLASMIC CALCIUM CHANGES ASSOCIATED WITH LYMPHOCYTE ACTIVATION

  1984cited by this paper
• Rapid loss of sensitivity of mitogen-induced lymphocyte activation to inhibition by cyclosporin A.

  1984cited by this paper
• Effect of cyclosporine on the generation of prostanoids by cultured peripheral lymphocytes.

  1984cited by this paper
• Suppressor T cell growth and differentiation. Identification of a cofactor required for suppressor T cell function and distinct from interleukin 2

  1984cited by this paper
• Mechanism of Action of Cyclosporin A

  1984cited by this paper
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  1984cited by this paper
• Deoxyadenosine (AdR) inhibition of newly activated lymphocytes: blockade at the G0-G1 interface.

  1984cited by this paper
• CHARACTERISTICS OF CYCLOSPORINE INDUCTION OF INCREASED PROSTAGLANDIN LEVELS FROM HUMAN PERIPHERAL BLOOD MONOCYTES

  1984cited by this paper
• Murine T cell suppression demonstrable in the absence of cytotoxicity and the effect of Cyclosporin A on this system.

  1983cited by this paper
• Inhibition of the production of a soluble helper mediator by cyclosporin A results in the failure to generate alloreactive cytolytic cells in mixed-lymphocyte culture.

  1983cited by this paper
• Gamma interferon synthesis by human thymocytes and T lymphocytes inhibited by cyclosporin A.

  1983cited by this paper
• Effect of cyclosporin A on human lymphocyte responses in vitro. V. Analysis of responding T lymphocyte subpopulations in primary MLR with monoclonal antibodies.

  1983cited by this paper
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  1983cited by this paper
• Treatment of intraocular inflammatory disease with cyclosporin A.

  1983cited by this paper
• Selective suppression of an early step in human B cell activation by cyclosporin A

  1983cited by this paper
• Effects of cyclosporin A on the metabolism of unstimulated and mitogen-activated lymphocytes.

  1983cited by this paper
• Permissive role of calcium in the inhibition of T cell mitogenesis by calmodulin antagonists.

  1983cited by this paper
• Effects of cyclosporin A (CyA) and methylprednisolone (MP) on the immune response. II. Further studies of the monocyte - T cell interactions leading to lymphokine production.

  1983cited by this paper
• Graft-versus-host disease in cyclosporin A-treated rats after syngeneic and autologous bone marrow reconstitution

  1983cited by this paper
• Effect of cyclosporin A on the induction and activation of B memory cells by thymus‐independent antigens in mice

  1983cited by this paper
• Cyclosporin A-treated guinea pig responder cells secrete a genetically restricted factor that suppresses the mixed leukocyte reaction.

  1983cited by this paper
• The role of calcium in lymphocyte proliferation. (An interpretive review).

  1983cited by this paper
• Cyclosporin A does not prevent expression of Tac antigen, a probable TCGF receptor molecule, on mitogen-stimulated human T cells.

  1983cited by this paper
• Abrogation of second-set rejection with cyclosporine.

  1983cited by this paper
• Antigen presenting cells in situ: their identification and involvement in immunopathology.

  1983cited by this paper
• Effect of cyclosporin A on lymphocyte activation by the calcium ionophore A23187.

  1983cited by this paper
• Cyclosporin a: Pharmacologic activity on the immune system and effects in clinical organ transplantation

  1983cited by this paper
• Prolongation of rat kidney allografts by pretransplant administration of donor antigen extract or whole blood transfusion combined with a short course of cyclosporine.

  1983cited by this paper
• Effect of cyclosporine on the response of normal human lymphocytes to cytomegalovirus in vitro

  1983cited by this paper
• Binding of cyclosporine by human lymphocytes and phospholipid vesicles.

  1983cited by this paper
• Suppression of delayed-type hypersensitivity reactions and lymphokine production by cyclosporin A in the mouse.

  1983cited by this paper
• Studies on induction and effector functions of concanavalin A-induced suppressor cells that limit TCGF production.

  1982cited by this paper
• Cyclosporin A

  1982cited by this paper
• Regulation of in vitro cytotoxic T lymphocyte generation. I. Evidence that killer cell precursors differentiate to effector cells in two steps

  1982cited by this paper
• Effect of cyclosporin A on the production of interferon by human peripheral blood leukocytes in vitro.

  1982cited by this paper
• Effect of cyclosporin A on human lymphocyte responses in vitro. IV. Production of T cell stimulatory growth factors and development of responsiveness to these growth factors in CsA-treated primary MLR cultures.

  1982cited by this paper
• The effects of cyclosporins on the cell cycle of t-lymphoid cell lines.

  1982cited by this paper
• Inhibition of T‐Cell Activity by Cyclosporin A

  1982cited by this paper
• Cyclosporin A: a powerful immunosuppressant.

  1982cited by this paper
• Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate.

  1982cited by this paper
• Interleukin 1 and T cell activation.

  1982cited by this paper
• Cyclosporin receptors on human lymphocytes.

  1982cited by this paper
• Effect of cyclosporin A on T cell function in vitro: the mechanism of suppression of T cell proliferation depends on the nature of the T cell stimulus as well as the differentiation state of the responding T cell.

  1982cited by this paper
• Effect of cyclosporin A on human lymphocyte responses in vitro. III. CsA inhibits the production of T lymphocyte growth factors in secondary mixed lymphocyte responses but does not inhibit the response of primed lymphocytes to TCGF.

  1982cited by this paper
• Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.

  1982cited by this paper
• Mechanism of T Cell Activation: Role and Functional Relationship of HLA‐DR Antigens and Interleukins

  1982cited by this paper
• Antigen dependence of cyclosporin A-induced allograft acceptance.

  1982cited by this paper
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  1982cited by this paper
• Concanavalin A triggers T lymphocytes by directly interacting with their receptors for activation.

  1982cited by this paper
• Selective inhibition of immunoregulatory cell functions by cyclosporin A.

  1982cited by this paper
• Cyclosporin A – Usefulness, Risks and Mechanism of Action

  1982cited by this paper
• Calmodulin as a mediator of hormone action and cell regulation

  1982cited by this paper
• Murine cytomegalovirus infection and cyclosporin A.

  1982cited by this paper
• Dissection of the proliferative and differentiative signals controlling murine cytotoxic T lymphocyte responses

  1982cited by this paper
• Calmodulin.

  1982cited by this paper
• Properties of cyclosporin--A-induced graft acceptance.

  1981cited by this paper
• Suppressive effects of cyclosporin A on the induction of alloreactivity in vitro and in vivo.

  1981cited by this paper
• Cyclosporin A.

  1981cited by this paper
• Cyclosporin A blocks receptors for HLA-DR antigens on T cells

  1981cited by this paper
• The specificity of post-cyclosporin "tolerance".

  1981cited by this paper
• Cyclosporin A abrogates proliferation of T cells and generation of suppressor and cytotoxic T-cell function induced by Epstein-Barr virus.

  1981cited by this paper
• In vitro activation of human suppressor cells: relative quantitation and specificity of suppressor cells generated in primary and secondary mixed lymphocyte cultures.

  1981cited by this paper
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  1981cited by this paper
• IMMUNE RESPONSES TO ORGAN ALLOGRAFTS: III. MARKED DECREASE IN MEDULLARY THYMOCYTES AND SPLENIC T LYMPHOCYTES AFTER CYCLOSPORIN A TREATMENT

  1981cited by this paper
• Cyclosporin A: Effects on the mouse thymus

  1981cited by this paper
• Suppressor cells in transplantation tolerance. II. maturation of suppressor cells in the bone marrow chimera.

  1981cited by this paper
• CYCLOSPORIN A SPARES SELECTIVELY LYMPHOCYTES WITH DONOR‐SPECIFIC SUPPRESSOR CHARACTERISTICS

  1981cited by this paper
• Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

  1981cited by this paper
• Mechanisms of cardiac allograft prolongation by cyclosporin-A.

  1981cited by this paper
• Cyclosporin-A--present experimental status.

  1981cited by this paper
• Orthotopic heart and combined heart and lung transplantation with cyclosporin-A immune suppression.

  1981cited by this paper
• Selective effects of cyclosporin A on functional B cell subsets in the mouse.

  1980cited by this paper

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• Free Bone Graft Attenuates Acute Rejection and in Combination with Cyclosporin A Leads to Indefinite Cardiac Allograft Survival1

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• The cyclosporins

  2008cites this paper
• Regulation of the NFAT pathway discriminates CD4+CD25+ regulatory T cells from CD4+CD25− helper T cells

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• UNIVERSIDADE DE SÃO PAULO FACULDADE DE ODONTOLOGIA DE BAURU

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• A Case of Nonspecific Interstitial Pneumonitis Improved After Cyclosporin Therapy.

  2003cites this paper
• Cytokines Regulate the Pattern of Rejection and Susceptibility to Cyclosporine Therapy in Different Mouse Recipient Strains After Cardiac Allografting1

  2003cites this paper
• Arginine modulated cyclosporine-induced immune suppression in rats transplanted with gastric cancer cells.

  2001cites this paper
• Cyclosporin A decreases human macrophage interleukin-6 synthesis at post-transcriptional level.

  1999cites this paper
• Effect of cyclosporin A on inflammatory cytokine production by human alveolar macrophages.

  1998cites this paper
• Action of cyclosporin A on mononuclear phagocytes.

  1996cites this paper
• The nonapeptide leucinostatin A acts as a weak ionophore and as an immunosuppressant on T lymphocytes.

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• Cyclosporin A in fat emulsion carriers: studies on the immunosuppressive potential, using the heterotopic heart transplant model in rats

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• Potential Interaction between Prolonged Cyclosporin Administration and Aging in the Rat Kidney

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• Immunopathogenic Mechanisms of Posttransfusion Graft-vs-Host Disease

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• PREVENTION OF GRAFT FAILURE BY CYCLOSPORINE IN RATS RECEIVING LYMPHOCYTE‐DEPLETED MHC‐MISMATCHED BONE MARROW

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• THE EFFECT OF THE CD28 ACTIVATION PATHWAY ON THE IMMUNOSUPPRESSIVE ACTION OF CYCLOSPORINE

  1991cites this paper
• Cyclosporine inhibits T-cell activation at two distinct levels: role of the CD 28 activation pathway.

  1991cites this paper
• Effect of cyclosporine on T lymphocyte development. Relationship to syngeneic graft-versus-host disease.

  1991cites this paper
• A study of cytokine production in acute graft-vs-host disease.

  1991cites this paper
• [Cyclosporine A in dermatology].

  1991cites this paper
• Effects of the immune system on cyclosporine absorption.

  1991cites this paper
• Glucocorticoid resistance in chronic asthma. Peripheral blood T lymphocyte activation and comparison of the T lymphocyte inhibitory effects of glucocorticoids and cyclosporin A.

  1991cites this paper
• Bone marrow transplantation

  1991cites this paper
• The Different Calcium Requirements of the Mitogenic Effects Elicited in Primary Neonatal Rat Hepatocytes by the Diterpene Phorbol Esters 12-O-Tetradecanoylphorbol-13-Acetate and Sapintoxin A

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  1991cites this paper
• Acute graft-versus-host disease.

  1990cites this paper
• Ca2+ release in permeabilized human neutrophils induced by ciclosporin.

  1990cites this paper
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  1990cites this paper
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  1990cites this paper
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  1990cites this paper
• Treatment of pemphigus vulgaris with cyclosporine. .

  1990cites this paper
• Lymphocytic infiltrates of the skin in association with cyclosporine therapy.

  1990cites this paper
• Differential regulation of interleukin 4 and interleukin 5 gene expression: a comparison of T-cell gene induction by anti-CD3 antibody or by exogenous lymphokines.

  1990cites this paper
• [Cyclosporin in autoimmune diseases].

  1990cites this paper
• Efficacy and toxicity of cyclosporine in chronic progressive multiple sclerosis: A randomized, double‐blinded, placebo‐controlled clinical trial

  1990cites this paper
• Graft-versus-host disease.

  1990cites this paper
• Immunological memory.

  1990cites this paper
• Cyclosporin A inhibits degranulation of rat basophilic leukemia cells and human basophils. Inhibition of mediator release without affecting PI hydrolysis or Ca2+ fluxes.

  1990cites this paper
• Cytomegalovirus infections in bone marrow transplant recipients given intensive cytoreductive therapy.

  1990cites this paper
• Canine models of bone marrow transplantation.

  1990cites this paper
• Cyclosporin A rapidly inhibits mediator release from human basophils presumably by interacting with cyclophilin.

  1990cites this paper
• Age-related factors in cyclosporine-induced syngeneic graft-versus-host disease: regulatory role of marrow-derived T lymphocytes

  1990cites this paper
• Analysis of the interactions of immunosuppressive drugs with cyclosporine in inhibiting DNA proliferation.

  1990cites this paper
• Influence of CsA on humoral immunity and on B lymphocyte activation

  1989cites this paper
• Comparison of immunosuppressive effects of cyclosporine A in a murine model of systemic candidiasis and of localized thrushlike lesions

  1989cites this paper
• MACROPHAGES AS TARGETS FOR INHIBITION BY CYCLOSPORINE

  1989cites this paper
• Age-related factors in the induction of syngeneic GVHD.

  1989cites this paper
• Biochemical characterization of the inhibitory effect of CsA on cytolytic T lymphocyte effector functions.

  1989cites this paper
• Allogeneic bone marrow transplantation after high-dose busulfan and cyclophosphamide in patients with acute nonlymphocytic leukemia.

  1989cites this paper
• ABOLITION OF THE EFFECT OF CYCLOSPORINE ON RAT CARDIAC ALLOGRAFT REJECTION BY THE NEW IMMUNOMODULATOR LS‐2616 (LINOMIDE)

  1989cites this paper
• Cyclosporin A: action and side-effects.

  1989cites this paper
• Immune mechanisms in cyclosporine-induced syngeneic graft-versus-host disease.

  1989cites this paper
• Effects of cyclosporin A on progressive and regressive tumors induced by two cancer lines derived from a single colon carcinoma chemically induced in the rat.

  1989cites this paper
• Syngeneic or autologous graft-versus-host disease.

  1989cites this paper
• Target cell specificity of immunosuppression in murine lymphocytes exposed to 1,4-bis[(2-aminoethyl)amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride (AEAD).

  1989cites this paper
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  1989cites this paper
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  1989cites this paper
• Cyclosporin in Dermatologic Disorders

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  1988cites this paper
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  1988cites this paper
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  1988cites this paper
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  1988cites this paper
• Syngeneic graft-versus-host disease after allogeneic bone marrow transplantation and cyclosporine treatment.

  1988cites this paper
• Mechanisms of action of cyclosporine: effect on cells of the immune system and on subcellular events in T cell activation.

  1988cites this paper
• In vitro effects of cyclosporines A and G on activation of an autoimmune T cell line.

  1988cites this paper
• Exacerbation of experimental pyelonephritis by cyclosporin A.

  1988cites this paper
• Acute Graft‐versus‐Host Disease: Clinical Characteristics in the Cyclosporine Era

  1988cites this paper
• Predictive Models of Graft versus Host Disease

  1988cites this paper
• Differential effects of cyclosporins A and G on functional activation of a T-helper-lymphocyte line mediating experimental autoimmune uveoretinitis.

  1988cites this paper
• The Use of Low Dose Cyclosporin A in a Case of Recalcitrant Erythrodermic Psoriasis

  1988cites this paper